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Infectious Disease: Influenza

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Total 27336 results found since Jan 2013.

Detection of Invasive Aspergillosis in Critically Ill Patients with Influenza: the Role of Plasma Galactomannan.
PMID: 31042411 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - April 30, 2019 Category: Respiratory Medicine Authors: van de Groep K, Verboom DM, van de Veerdonk FL, Haas PA, van der Poll T, Schultz MJ, Bonten MJM, Cremer OL, MARS consortium Tags: Am J Respir Crit Care Med Source Type: research

Safety and Adverse Events after Targeted Lung Denervation for Symptomatic Moderate to Severe COPD (AIRFLOW): A Multicenter Randomized Controlled Trial.
CONCLUSIONS: Patients with symptomatic COPD treated with TLD combined with optimal pharmacotherapy had fewer study defined respiratory adverse events, including hospitalizations for COPD exacerbation. Clinical trial registration available at clinicaltrials.gov, ID: NCT02058459. PMID: 31404499 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - August 11, 2019 Category: Respiratory Medicine Authors: Slebos DJ, Shah PL, Herth FJ, Pison C, Schumann C, Hübner RH, Bonta PI, Kessler R, Gesierich W, Darwiche K, Lamprecht B, Perez T, Skowasch D, Deslee G, Marceau A, Sciurba FC, Gosens R, Hartman JE, Srikanthan K, Duller M, Valipour A, AIRFLOW-2 Trial Study Tags: Am J Respir Crit Care Med Source Type: research

Dynamics of IFN- β Responses During Respiratory Viral Infection: Insights for Therapeutic Strategies.
CONCLUSIONS: In vitro modelling of IFN-β dynamics highlights the potential for intermittent prophylactic doses of exogenous IFN-β to modulate viral infection. This provides important insights to aid the future design of clinical trials of IFN-β in asthma and COPD. PMID: 31461630 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - August 27, 2019 Category: Respiratory Medicine Authors: Watson A, Spalluto CM, McCrae C, Cellura D, Burke H, Cunoosamy D, Freeman A, Hicks A, Hühn M, Ostridge K, Staples KJ, Vaarala O, Wilkinson T Tags: Am J Respir Crit Care Med Source Type: research

Influenza Infections and Emergent Viral Infections in Intensive Care Unit
In this study, we aim to analyze the current evidence and findings associated with influenza and other emergent viral infections, namely, herpes simplex virus type 1 (HSV-1), Epstein-Barr virus (EBV), and cytomegalovirus (CMV).Among medical conditions, community-acquired respiratory infections are the most frequent reason for ventilatory support in ICUs. Community-acquired pneumonia in a severe form including the need of invasive mechanical ventilation and/or vasopressors is associated with high mortality rates. However, after the pandemic that occurred in 2009 by H1N1 influenza, the number of cases being admitted to ICUs ...
Source: Seminars in Respiratory and Critical Care Medicine - October 3, 2019 Category: Respiratory Medicine Authors: Cantan, Ben Luyt, Charles-Edouard Martin-Loeches, Ignacio Tags: Review Article Source Type: research

Invasive Tracheobronchial Aspergillosis in Critically Ill Patients with Severe Influenza.
CONCLUSIONS: Invasive tracheobronchial aspergillosis was associated with higher severity scores, mortality, serum and BALF Galactomannan and Beta-D Glucan levels than IPA patients without tracheobronchial lesions. ITBA should be systematically researched by bronchoscopic examination in ICU patients with concomitant pulmonary aspergillosis and influenza. PMID: 32407157 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - May 13, 2020 Category: Respiratory Medicine Authors: Nyga R, Maizel J, Nseir S, Chouaki T, Milic I, Roger PA, Van Grunderbeeck N, Lemyza M, Totet A, Castelain S, Slama M, Dupont H, Sendid B, Zogheib E Tags: Am J Respir Crit Care Med Source Type: research

Invasive Aspergillus Tracheobronchitis Emerging as Highly Lethal Complication of Severe Influenza.
PMID: 32520582 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - June 9, 2020 Category: Respiratory Medicine Authors: van de Veerdonk FL, Wauters J, Verweij PE Tags: Am J Respir Crit Care Med Source Type: research

Recombinant MG53 Protein Protects Mice from Lethal Influenza Virus Infection.
PMID: 33031705 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - October 8, 2020 Category: Respiratory Medicine Authors: Kenney AD, Li Z, Bian Z, Zhou X, Li H, Whitson BA, Tan T, Cai C, Ma J, Yount JS Tags: Am J Respir Crit Care Med Source Type: research

Intensive Care Unit Preparedness During Pandemics and Other Biological Threats
In the twenty-first century, severe acute respiratory syndrome (SARS), 2009 A(H1N1) influenza, and Ebola have all placed strains on critical care systems. In addition to the increased patient needs common to many disasters, epidemics may further degrade ICU capability when staff members fall ill, including in the course of direct patient care. In a large-scale pandemic, shortages of equipment and medications can further limit an ICU ’s ability to provide the normal standard of care. Hospital preparedness for epidemics must include strategies to maintain staff safety, secure adequate supplies, and have plans for triage an...
Source: Critical Care Clinics - July 11, 2019 Category: Intensive Care Authors: Ryan C. Maves, Christina M. Jamros, Alfred G. Smith Source Type: research

Influenza Virus-Related Critical Illness Influenza Virus-Related Critical Illness
When should influenza be considered in patients admitted to the ICU, and how are the associated complications best treated?Critical Care
Source: Medscape Today Headlines - July 17, 2019 Category: Consumer Health News Tags: Critical Care Journal Article Source Type: news

Preparing Intensive Care for the Next Pandemic Influenza Preparing Intensive Care for the Next Pandemic Influenza
Are ICUs adequately prepared for the next major flu pandemic?Critical Care
Source: Medscape Today Headlines - November 27, 2019 Category: Consumer Health News Tags: Critical Care Journal Article Source Type: news

A cross-sectional survey of Australian and New Zealand public opinion on methods totriage intensive care patients in an influenza pandemic.
CONCLUSION: In an influenza pandemic, when ICU resources would be overwhelmed, survey respondents preferred that ICU triage be performed by a senior doctor, but also perceived the use of pre-determined triage criteria to be fair. PMID: 28866976 [PubMed - in process]
Source: Critical Care and Resuscitation - September 6, 2017 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Intensive care medicine research agenda on invasive fungal infection in critically ill patients
ConclusionsFundamental questions regarding IFI have to be addressed over the next decade. The clinical studies described in this research agenda should provide a template and set priorities for the clinical investigations that need to be performed.
Source: Intensive Care Medicine - March 1, 2017 Category: Intensive Care Source Type: research

Research and Reviews in the Fastlane 056
This article offers solutions in which he calls for a shift in the research mentality. The pearls: Focus on replication of research findings (and reward this) Broad collaboration and data sharing Altering the reward system for publication and academic advancement (i.e. reward not the number of publications but their impact; focus on the quality of peer review) Recommended by Lauren Westafer Resuscitation, Emergency MedicineSmekal D et al. CPR-related injuries after manual or mechanical chest compressions with the LUCAS™ device: A multicentre study of victims after unsuccessful resuscitation. Resuscitation 2014. PMID ...
Source: Life in the Fast Lane - November 4, 2014 Category: Emergency Medicine Authors: Soren Rudolph Tags: Cardiology Education Emergency Medicine Infectious Disease Intensive Care Neurology Neurosurgery R&R in the FASTLANE Resuscitation Wilderness Medicine acute coronary syndrome airway blood transfusion critical care ENT Review Source Type: blogs

Research and Reviews in the Fastlane 079
This article is a meta-analysis looking at a relatively new technique: POC Ultrasound. This review found that for ED intubations, US had a sensitivity of 98% and a specificity of 94%. The question, however, should be whether this technique is faster than End Tidal CO2, which is extremely reliable.Recommended by: Anand SwaminathanRead More: Ultrasound for Verification of Endotracheal Tube Location (ALiEM)The R&R iconoclastic sneak peek icon keyThe list of contributorsThe R&R ARCHIVER&R Hall of famer You simply MUST READ this!R&R Hot stuff! Everyone’s going to be talking about thisR&R Landmark pap...
Source: Life in the Fast Lane - April 16, 2015 Category: Emergency Medicine Authors: Anand Swaminathan Tags: Airway Emergency Medicine Infectious Disease Intensive Care Pediatrics Respiratory Toxicology and Toxinology Trauma critical care Education literature R&R in the FASTLANE recommendations research and reviews Source Type: blogs

Research and Reviews in the Fastlane 038
This study, however, has major flaws and biases that question the validity of their conclusions. Only 19% of centers that were contacted agreed to contribute data to the Consortium. Additionally, the researchers do not assess the quality of the studies included in their meta-analysis. Regardless, observational data should not be used to trump the RCT data included in the recent, Cochrane review. Finally, Roche pharmaceuticals was a major sponsor of this research team. The accompanying editorial is a must-read. Recommended by: Anand Swaminathan Infection Control, Hand hygiene D’Egidio G et al. A study of the ...
Source: Life in the Fast Lane - July 10, 2014 Category: Emergency Medicine Authors: Nudrat Rashid Tags: Anaesthetics Cardiology Emergency Medicine Featured Infectious Disease Intensive Care Neurology Palliative care R&R in the FASTLANE Radiology Resuscitation Trauma critical care literature recommendations research and reviews Source Type: blogs