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Total 116 results found since Jan 2013.
A synthetic delivery vector for mucosal vaccination
Biomaterials. 2023 Sep 5;302:122298. doi: 10.1016/j.biomaterials.2023.122298. Online ahead of print.ABSTRACTThe success of mRNA-based vaccines during the Covid-19 pandemic has highlighted the value of this new platform for vaccine development against infectious disease. However, the CD8+ T cell response remains modest with mRNA vaccines, and these do not induce mucosal immunity, which would be needed to prevent viral spread in the healthy population. To address this drawback, we developed a dendritic cell targeting mucosal vaccination vector, the homopentameric STxB. Here, we describe the highly efficient chemical synthesi...
Source: Biomaterials - September 15, 2023 Category: Materials Science Authors: Anne Billet Justine Hadjerci Thi Tran Pascal Kessler Jonathan Ulmer Gilles Mourier Marine Ghazarian Anthony Gonzalez Robert Thai Pauline Urquia Anne-C écile Van Baelen Annalisa Meola Ignacio Fernandez St éphanie Deville-Foillard Ewan MacDonald L éa Pao Source Type: research
Vaccination Coverage Among Adolescents Aged 13-17 Years - National Immunization Survey-Teen, United States, 2022
MMWR Morb Mortal Wkly Rep. 2023 Aug 25;72(34):912-919. doi: 10.15585/mmwr.mm7234a3.ABSTRACTThree vaccines are routinely recommended for adolescents to prevent pertussis, meningococcal disease, and cancers caused by human papillomavirus (HPV). CDC analyzed data from the 2022 National Immunization Survey-Teen for 16,043 adolescents aged 13-17 years to assess vaccination coverage. Birth cohort analyses were conducted to assess trends in vaccination coverage by age 13 years (i.e., before the 13th birthday) and by age 14 years (i.e., before the 14th birthday) among adolescents who were due for routine vaccination before and dur...
Source: MMWR Morb Mortal Wkl... - August 24, 2023 Category: Epidemiology Authors: Cassandra Pingali David Yankey Laurie D Elam-Evans Lauri E Markowitz Madeleine R Valier Benjamin Fredua Samuel J Crowe Carla L DeSisto Shannon Stokley James A Singleton Source Type: research
Opportunities to accelerate immunization progress in middle-income countries
Vaccine. 2023 Jul 15:S0264-410X(23)00782-X. doi: 10.1016/j.vaccine.2023.06.079. Online ahead of print.ABSTRACTThere has been increasing recognition of vaccine access challenges in middle-income countries and the need for increased action, particularly in countries that are not eligible for or have transitioned out of Gavi, the Vaccine Alliance support. These countries' immunization systems are more vulnerable than ever as the COVID-19 pandemic exacerbates existing programme challenges, increasing the risk of delayed vaccine introductions, backsliding immunization coverage rates, and increased coverage inequity. The potenti...
Source: Vaccine - July 17, 2023 Category: Allergy & Immunology Authors: Jason Zhu Clarke B Cole Johanna Fihman Alex Adjagba Mira Dasic Tania Cernuschi Source Type: research
Status of New Vaccine Introduction - Worldwide, 2016-2021
This report describes the status of introductions globally for eight World Health Organization (WHO)-recommended new and underutilized vaccines, comprising 10 individual vaccine antigens. By 2021, among 194 countries worldwide, 33 (17%) provided all of these 10 WHO-recommended antigens as part of their routine immunization schedules; only one low-income country had introduced all of these recommended vaccines. Universal hepatitis B birth dose; human papillomavirus vaccine; rotavirus vaccine; and diphtheria, tetanus, and pertussis-containing vaccine first booster dose have been introduced by 57%, 59%, 60%, and 72% of all co...
Source: MMWR Morb Mortal Wkl... - July 6, 2023 Category: Epidemiology Authors: Gurpreet Kaur Rebecca M Casey Jaymin C Patel Paul Bloem Jenny A Walldorf Terri B Hyde Source Type: research
Gastrointestinal tract and viral pathogens
World J Virol. 2023 Jun 25;12(3):136-150. doi: 10.5501/wjv.v12.i3.136.ABSTRACTViral gastroenteritis is the most common viral illness that affects the gastrointestinal (GI) tract, causing inflammation and irritation of the lining of the stomach and intestines. Common signs and symptoms associated with this condition include abdominal pain, diarrhea, and dehydration. The infections commonly involved in viral gastroenteritis are rotavirus, norovirus, and adenovirus, which spread through the fecal-oral and contact routes and cause non-bloody diarrhea. These infections can affect both immunocompetent and immunocompromised indiv...
Source: Herpes - July 3, 2023 Category: Infectious Diseases Authors: Gowthami Sai Kogilathota Jagirdhar Yashwitha Sai Pulakurthi Himaja Dutt Chigurupati Salim Surani Source Type: research
