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Infectious Disease: COVID-19
Nutrition: Antidoxidants

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Total 538 results found since Jan 2013.

Ebselen: A Review on its Synthesis, Derivatives, Anticancer Efficacy and Utility in Combating SARS-COV-2
Mini Rev Med Chem. 2023 Sep 14. doi: 10.2174/1389557523666230914103339. Online ahead of print.ABSTRACTEbselen is a selenoorganic chiral compound with antioxidant properties comparable to glutathione peroxidase. It is also known as 2-phenyl-1,2-benzisoselenazol-3(2H)-one. In studies examining its numerous pharmacological activities, including antioxidant, anticancer, antiviral, and anti-Alzheimer's, ebselen has demonstrated promising results. This review's primary objective was to emphasize the numerous synthesis pathways of ebselen and their efficacy in fighting cancer. The data were collected from multiple sources, includ...
Source: Mini Reviews in Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Farak Ali Shahnaz Alom Sheikh Rezzak Ali Biswanarayan Kondoli Prativa Sadhu Chinmoyee Borah Bibhuti Bushan Kakoti Surajit Kumar Ghosh Anshul Shakya Abdul Baquee Ahmed Udaya Pratap Singh Hans Raj Bhatt Source Type: research

Broad-Spectrum Antiviral Effect of Cannabidiol Against Enveloped and Nonenveloped Viruses
Conclusions: It was demonstrated that CBD inhibits structurally dissimilar viruses, suggesting that this phytochemical has broad-spectrum antiviral effect, representing a valuable alternative in emergency situations during viral outbreaks, like the one caused by severe acute respiratory syndrome coronavirus 2 in 2020.PMID:37682578 | DOI:10.1089/can.2023.0103
Source: Cell Research - September 8, 2023 Category: Cytology Authors: Agostina B Marquez Josefina Vicente Eliana Castro Daiana Vota Mar ía S Rodríguez-Varela Priscila A Lanza Castronuovo Giselle M Fuentes Alejandro R Parise Leonardo Romorini Diego E Alvarez Carlos A Bueno Cristina L Ramirez Agustina Alaimo Cybele C Garc à Source Type: research

Activation of Nrf2/ARE pathway by Anisodamine (654-2) for Inhibition of cellular aging and alleviation of Radiation-Induced lung injury
CONCLUSION: 654-2 can activate the Nrf2/ARE pathway, enhance cellular antioxidant capacity, and inhibit cellular senescence, thereby exerting a protective effect against RILI.PMID:37678028 | DOI:10.1016/j.intimp.2023.110864
Source: International Immunopharmacology - September 7, 2023 Category: Allergy & Immunology Authors: Haochun Guo Jiajia Chen Hanxu Yu Lei Dong Ran Yu Qingju Li Jian Song Haoyu Chen Haijun Zhang Juan Pu Wanpeng Wang Source Type: research

Post-COVID-19 cryptosporidiosis: A serious risk or mere association?
This study analyzed gastrointestinal symptoms, medical histories, fecal Cryptosporidium oocysts, and the history of COVID-19 infection in patients who attended the Faculty of Medicine, Cairo University, from January to July 2021. Fecal biomarkers, including H. pylori, occult blood, fecal calprotectin (FCAL), and TNF-a, were measured, and Cryptosporidium spp. genotypes were molecularly characterized among post-COVID-19 patients using RFLP. Preliminary results from 210 post-COVID-19 patients revealed that group 1 (Cryptosporidiumpositive) (n = 49) and group 2 (Cryptosporidium-negative) (n = 161) showed no significant differe...
Source: Tropical Biomedicine - August 31, 2023 Category: Tropical Medicine Authors: A E Enas M A Hadel A A Emad B E Ibrahim S Morsy M A Noha Source Type: research