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Infectious Disease: H3N2
Vaccination: Influenza Vaccine
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Total 487 results found since Jan 2013.
Association of vaccine-specific regulatory T cells with reduced antibody response to repeated influenza vaccination
This article is protected by copyright. All rights reserved.PMID:37713727 | DOI:10.1002/eji.202350525
Source: European Journal of Immunology - September 15, 2023 Category: Allergy & Immunology Authors: Pin-Hung Lin Po-Ju Hsiao Ching-Fu Pan Ming-Tsan Liu Jann-Tay Wang Chi Ching Fang-Yi Wu Yi-Hsuan Lin Yu-Chan Yang Le-Yin Hsu Hung-Chih Yang Un-In Wu Source Type: research
The re-emergence of influenza following the COVID-19 pandemic in Victoria, Australia, 2021 to 2022
ConclusionEnhanced testing for respiratory viruses during the COVID-19 pandemic provided a more complete picture of influenza virus transmission compared with previous seasons. Returned international travellers were important drivers of influenza reemergence, as were young adults, a group whose role has previously been under-recognised in the establishment of seasonal influenza epidemics. Targeting interventions, including vaccination, to these groups could reduce future influenza transmission.PMID:37707981 | DOI:10.2807/1560-7917.ES.2023.28.37.2300118
Source: Euro Surveill - September 14, 2023 Category: Infectious Diseases Authors: Catherine Ga Pendrey Janet Strachan Heidi Peck Ammar Aziz Jean Moselen Rob Moss Md Rezanur Rahaman Ian G Barr Kanta Subbarao Sheena G Sullivan Source Type: research
A recombinant chimeric influenza virus vaccine expressing the consensus H3 hemagglutinin elicits broad hemagglutination inhibition antibodies against divergent swine H3N2 influenza viruses
This study focuses on the hemagglutinin (HA) consensus-based approach towards developing a more broadly protective swine influenza vaccine against various H3 strains circulating in domestic pig populations. By computationally analyzing >1000 swine H3 full-length HA sequences, we generated a consensus H3 and expressed it in the context of influenza A WSN/33 reverse genetics system. The derived recombinant chimeric swine influenza virus with the consensus H3 was inactivated and further evaluated as a potential universal vaccine in pigs. The consensus H3 vaccine elicited broadly active hemagglutination inhibition (HI) anti...
Source: Vaccine - September 9, 2023 Category: Allergy & Immunology Authors: Jieshi Yu Chithra Sreenivasan Zhizhang Sheng Shao-Lun Zhai Jared W Wollman Sisi Luo Chen Huang Rongyuan Gao Zhao Wang Radhey S Kaushik Jane Christopher-Hennings Eric Nelson Ben M Hause Feng Li Dan Wang Source Type: research
The Adenylyl Cyclase Activator Forskolin Increases Influenza Virus Propagation in MDCK Cells by Regulating ERK1/2 Activity
In this study, we investigated whether treatment with forskolin (FSK), an adenylyl cyclase activator, affected the output of a cell-based influenza vaccine. We found that FSK increased the propagation of three influenza virus subtypes (A/H1N1/California/4/09, A/H3N2/Mississippi/1/85, and B/Shandong/7/97) in Madin-Darby canine kidney (MDCK) cells. Interestingly, FSK suppressed the growth of MDCK cells. This effect could be a result of protein kinase A (PKA)-Src axis activation, which downregulates extracellular signal-regulated kinase (ERK)1/2 activity and delays cell cycle progression from G1 to S. This delay in cell growt...
Source: Journal of Microbiology and Biotechnology - August 30, 2023 Category: Biotechnology Authors: Sang-Yeon Lee Jisun Lee Hye-Lim Park Yong-Wook Park Hun Kim Jae-Hwan Nam Source Type: research
