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Developing a New Score: How Machine Learning Improves Risk Prediction
Composite risk scores have been used for decades to identify disease risk and health status in the general population. However, current approaches often fail to identify people who would benefit from intervention or recommend unnecessary intervention. Machine learning promises to improve accuracy, ensuring targeted treatment for patients that need it and reducing unnecessary intervention.
Framingham Risk Score, the gold standard for predicting the likelihood of heart disease, predicts hospitalizations with about 56% accuracy. It uses factors such as age, gender, smoking, cholesterol levels, and systolic blood pressure to...
Source: MDDI - November 17, 2017 Category: Medical Devices Authors: Heather R. Johnson Tags: R & D Source Type: news
Whatever it takes: Fighting for Michael
Michael stood at the top of the hill, staring down at the glittering white snow. The prospect of skiing to the bottom was scary — on previous trips, he’d refused to try, worried that he would fall. But this time was different. He was ready to take a chance. Attempting to balance without using poles, he pushed himself forward and glided through the powder as his family cheered him on. By the end of the day, the 8-year-old had sailed down the slopes five times, all by himself.
The accomplishment was even more meaningful for his parents, Bill and Lisa Smith, who have watched him fight to survive — and thrive — since h...
Source: Thrive, Children's Hospital Boston - November 30, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Center for Advanced Intestinal Rehabilitation Dr. Tom Jaksic G-J tube Hale Center for Families short bowel syndrome (SBS). volvulus Source Type: news
Neuroscientists show deep brain waves occur more often during navigation and memory formation
FINDINGSUCLA neuroscientists are the first to show that rhythmic waves in the brain called theta oscillations happen more often when someone is navigating an unfamiliar environment, and that the more quickly a person moves, the more theta oscillations take place — presumably to process incoming information faster.In an unexpected finding, theta oscillations were most prominent in a blind person who relied on a cane to move. The scientists hypothesized that a sightless person explores a strange environment through multiple senses, which would require more brain activity to process the extra sensory input.BACKGROUNDTheta o...
Source: UCLA Newsroom: Health Sciences - December 11, 2017 Category: Universities & Medical Training Source Type: news
New treatment for SMA offers hope for Arianna
For the first few months of Arianna Condon’s life, everything was moving along fine. She was a happy baby, and seemed to be developing much like her older sister, Tessa.
“She was gaining weight, and seemed to be doing great,” says Arianna’s mom, Marina. “She did have problems with reflux, but it was nothing too unusual for a baby.”
But by the time Arianna was 3 months old, Marina started to have concerns. Arianna wasn’t lifting her head the way Tessa had at that age. Something didn’t seem right.
“I brought it up to her pediatrician, but she told me that all babies develop differently and there wasn’t a ...
Source: Thrive, Children's Hospital Boston - January 16, 2018 Category: Pediatrics Authors: Ellen Greenlaw Tags: Diseases & Conditions Our Patients’ Stories Dr. Basil Darras spinal muscular atrophy spinal muscular atrophy program Spinraza Source Type: news
Not as Simple as Canker Sores
BY NANA P. MATSUMOTO, & DEREK MEEKS, DOA 16-year-old boy presented to a rural ED with a swollen jaw, painful blisters in the mouth, and earache for the past day. One week before, he had a fever with chills, sore throat, and dry coughs. He was not taking any medications, and his immunizations were up-to-date. He had a mild learning disorder but no significant past medical or surgical history.An apthous ulcer, the most common and one of the earliest signs of Behçet's disease.The patient's vital signs were within normal limits, and his physical examination revealed anterior cervical lymphadenopathy, sinus con...
Source: The Case Files - October 11, 2017 Category: Emergency Medicine Tags: Blog Posts Source Type: research
10 Global Health Issues to Watch in 2018
January 19, 2018It ’s notallbad news.When we set out to compile our annual list of global health issues to watch this year, it seemed like all bad news. And true, that ’s often what we deal with in global health—the problems that need tackling, the suffering we can help alleviate.But then stories and columns likethis one cheer us up. They remind us that no matter how complicated and frustrating our work may get, fighting back against poverty and inequality works.There are and always will be global health challenges to face. But there ’s boundless hope, too. And a field full of determined health workers and other hu...
Source: IntraHealth International - January 19, 2018 Category: International Medicine & Public Health Authors: mnathe Source Type: news
Teamwork and toughness: Living with cerebral palsy
Growing up in Querétaro, Mexico, María was an exceptionally bright and inquisitive child. At just 18 months old, she spoke at the level of a 6-year-old, and could even sing the tongue-twisting “Supercalifragilisticexpialidocious” song. Her parents marveled at her intelligence at such a young age, but there was something in her development that seemed off.
“At 1 year, she wasn’t crawling well and had difficulty standing,” her mother, María José, recalls. “She hadn’t learned to walk by 18 months, and she would crawl by pulling her two legs at the same time — like a little bunny.” Her parents knew that s...
Source: Thrive, Children's Hospital Boston - February 2, 2018 Category: Pediatrics Authors: Connor Ertz Tags: Our Patients’ Stories cerebral palsy Cerebral Palsy Center Child and Young Adult Hip Preservation Program Dr. Benjamin Shore Dr. Donna Nimec Source Type: news
DataFlash: Data Indexers
The Institute for Health Metrics and Evaluation (IHME) is “an independent population health research center at UW Medicine, part of the University of Washington, that provides rigorous and comparable measurement of the world’s most important health problems and evaluates the strategies used to address them.” Their mission is to improve the health of the world’s populations by providing the best information on population health, and to do so, IHME enlists the expertise of countless individuals, including researchers, data analysts, data scientists, and thirteen data indexers. What is a data indexer? ...
Source: Dragonfly - April 2, 2018 Category: Databases & Libraries Authors: Ann Madhavan Tags: Data Science Source Type: news
5 Trends Medtech Should Be Talking About
Recently I chatted with Candace Roulo, managing editor of Advanced Manufacturing Now, about some of the most important trends in medtech and the technologies that are taking the industry to the next level. Click below to listen to the podcast, or read on for select highlights of the conversation – what I consider to be five trends medtech professionals should be talking about.
128-Advanced_Manufacturing_Now-UBM.mp3
Explore all of these trends in depth at the BIOMEDevice Boston Conference and Expo, April 18-19, 2018. Use promo code "SAVE100" for $100 off conference registration and free expo access.
1. Muc...
Source: MDDI - April 6, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: BIOMEDevice Boston Business Digital Health Source Type: news
Statins associated with improvement of rare lung disease
This study suggests that oral statin therapy may be a new approach for patients with autoimmune pulmonary alveolar proteinosis.AUTHORSThe study ’s co-senior authors are Dr. Elizabeth Tarling of UCLA and Dr. Bruce Trapnell of Children’s Hospital Medical Center of Cincinnati, Ohio. Other authors are listed in the journal article.JOURNALThe study was published in the journal Nature Communications. FUNDINGThe National Institutes of Health funded the research.Learn more about the cardiovascular research theme at UCLA.
Source: UCLA Newsroom: Health Sciences - August 17, 2018 Category: Universities & Medical Training Source Type: news
Pulmonary embolism with migrating thrombus through patent foramen ovale: A case for a mixed pharmacological and percutaneous management
Publication date: Available online 27 September 2018Source: Journal of Cardiology CasesAuthor(s): Gloria Santangelo, Alfonso Ielasi, Francesco Pattarino, Antonio Tommaso Saino, Pasquale Antonio Scopelliti, Maurizio TespiliAbstractA 61-year-old man, admitted to our hospital for bilateral pulmonary embolism, complicated by right renal ischemia and multiple splenic infarcts due to a mobile thrombus entrapped in a patent foramen ovale, has been successfully treated with apixaban 5 mg twice daily followed by transcatheter patent foramen ovale closure.<Learning objective: Apixaban could be a therapeutic alternative to t...
Source: Journal of Cardiology Cases - October 4, 2018 Category: Cardiology Source Type: research
Should You Take Aspirin Every Day? Here ’s What the Science Says
Aspirin is best known as an over-the-counter painkiller. But acetylsalicylic acid, as it’s called chemically, has many other health benefits, as well as side effects, in the body that have only become clear in recent years.
Here’s what the latest science says about the health benefits and side effects of aspirin, as well as which conditions it may treat and those it doesn’t appear to improve. (If you are taking aspirin for any reason other than for periodic pain relief, it’s best to consult with your doctor to confirm whether the benefits outweigh the risks in your particular case.)
How aspirin affe...
Source: TIME: Health - November 8, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Drugs healthytime Source Type: news
Intracranial Hemorrhage Detection Software Receives FDA Clearance
“AI and machine learning are going to transform healthcare, as they have virtually every other industry they have touched,†said Gene Saragnese, chairman and CEO of MaxQ AI in an interview with MD+DI. “Our world is surrounded by algorithms that present information, but one place it’s been lacking is healthcare.â€
MaxQ AI is doing its best to remedy that deficiency, starting with software that can detect intracranial hemorrhage (ICH). The company’s recently FDA-cleared Accipio Ix is used with noncontrast co...
Source: MDDI - November 17, 2018 Category: Medical Devices Authors: Susan Shepard Tags: Digital Health Source Type: news
Predict and Prevent: The Emergence of Real-Time Sensor-Based Care
Technology industry veteran Eran Ofir knows there is a lot of luck involved in successfully bringing a new device, especially one designed to create a new treatment vector, to market.
Ofir is the CEO and co-founder of New York-based Somatix, which uses wrist-worn sensor data to dynamically monitor a person's situation. Used in conjunction with cloud-based computing resources and a communications device, the technology is capable of dynamically helping someone quit smoking, through detecting smoking gestures and automatically sending messages to the user encouraging them not to smoke.
"We got lucky on two fronts," Ofir said...
Source: MDDI - December 19, 2018 Category: Medical Devices Authors: Greg Goth Tags: Digital Health Source Type: news
Automatic Segmentation of Left Ventricle from Cardiac MRI via Deep Learning and Region Constrained Dynamic Programming
Publication date: Available online 16 February 2019Source: NeurocomputingAuthor(s): Hu Huaifei, Ning Pan, Jiayu Wang, Tailang Yin, Renzhen YeAbstractSegmentation of the left ventricle from cardiac magnetic resonance images (MRI) is an essential step to quantitatively analyze global and regional cardiac function. The aim of this study is to develop a novel and robust algorithm which can improve the accuracy of automatic left ventricle segmentation on short-axis cardiac MRI. The database used in this study are 900 cardiac MRI cases from Hubei Cancer Hospital. Three key techniques are developed in this segmentation algorithm:...
Source: Neurocomputing - February 16, 2019 Category: Neuroscience Source Type: research
