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Clinical import of Horner syndrome in internal carotid and vertebral artery dissection
Conclusion: In patients with ICAD, HS is an easily assessable marker that might indicate a more benign clinical course. HS had no prognostic meaning in patients with VAD.
Source: Neurology - May 5, 2014 Category: Neurology Authors: Lyrer, P. A., Brandt, T., Metso, T. M., Metso, A. J., Kloss, M., Debette, S., Leys, D., Caso, V., Pezzini, A., Bonati, L. H., Thijs, V., Bersano, A., Touze, E., Gensicke, H., Martin, J. J., Lichy, C., Tatlisumak, T., Engelter, S. T., Grond-Ginsbach, C., F Tags: Stroke in young adults, Carotid artery dissection ARTICLE Source Type: research

Quantifying Cerebral Collaterals In Carotid Artery Dissection May Help Stratify Stroke Risk. (P3.110)
CONCLUSIONS: These uncontrolled data suggest that a quantified score of distal cerebral collaterals could help stratify stroke risk and help guide management in patients with carotid artery dissection. Further controlled, prospective study in a larger and more diverse sample is warranted.Study Supported by: AHA/ASA NCRP 13CRP14140001Disclosure: Dr. Southerland has received personal compensation in an editorial capacity for Neurology Podcast. Dr. Gaughen has received personal compensation for activities with Covidien Neurovascular, Microvention, and Stryker Neurovascular as a consultant. Dr. McMurry has nothing to disclose....
Source: Neurology - April 9, 2014 Category: Neurology Authors: Southerland, A., Gaughen, J., McMurry, T., Wintermark, M., Majersik, J., Worrall, B. Tags: Cerebrovascular Disease and Interventional Neurology: Large Vessel Nonatherosclerotic Arteriopathies Source Type: research

Ischemic Stroke And Cervical Artery Dissection. Risk Factors And Functional Outcome In a Single Tertiary Care Hospital: The Clinica Alemana Stroke Registry (RECCA), 1997-2003 (P3.111)
ConclusionsThe prognosis of ischemic stroke patients with cervical artery dissections is generally good. The only variable associated with a worse prognosis, was a high NIHSS at admission. This allows early identification of a group of patients who are at increased risk of significant disability at discharge.Disclosure: Dr. Diaz has nothing to disclose. Dr. Vicuña has nothing to disclose. Dr. Fernandez has nothing to disclose. Dr. Valenzuela has nothing to disclose. Dr. Lavados has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Diaz, V., Vicuna, M., Fernandez, J., Valenzuela, M., Lavados, P. Tags: Cerebrovascular Disease and Interventional Neurology: Large Vessel Nonatherosclerotic Arteriopathies Source Type: research

Stroke in first‐degree relatives of patients with cervical artery dissection
ConclusionRelatives of CeAD patients had fewer strokes at a young age than relatives of non‐CeAD IS stroke patients.
Source: European Journal of Neurology - April 2, 2014 Category: Neurology Authors: M. Kloss, C. Grond‐Ginsbach, A. Pezzini, T. M. Metso, A. J. Metso, S. Debette, D. Leys, J. Dallongeville, V. Caso, V. Thijs, A. Bersano, E. Touzé, L. H. Bonati, T. Tatlisumak, M.‐L. Arnold, P. A. Lyrer, S. T. Engelter, Tags: Original Article Source Type: research

The Association Between Cervical Spine Manipulation and Carotid Artery Dissection: A Systematic Review of the Literature
Controversy surrounds the safety of cervical spine manipulation. Ischemic stroke secondary to cervical spine manipulation is a hypothesized adverse event. In Canada, the seriousness of these events and their perceived association to cervical spine manipulation has led some members of the public to call for a ban of the procedure. The primary objective of this study was to determine the incidence of internal carotid artery (ICA) dissection after cervical spine manipulation in patients who experience neck pain and its associated disorders.
Source: Journal of Manipulative and Physiological Therapeutics - January 6, 2014 Category: Complementary Medicine Authors: Chadwick L.R. Chung, Pierre Côté, Paula Stern, Georges L'Espérance Tags: Special Articles: Adverse Events Source Type: research

Differences and Similarities Between Spontaneous Dissections of the Internal Carotid Artery and the Vertebral Artery
There are clinical, pathologic, and outcome differences in spontaneous dissections of the internal carotid artery vs those of the vertebral artery. Spontaneous cervical artery dissection is a major cause of stroke in younger patients. Spontaneous cervical artery dissection causes up to 25% of all ischemic strokes in patients 15 to 49 years of age (Putaala J et al, Stroke 2009;40:1195-203). Although constitutional and environmental factors are both thought to play a role in spontaneous cervical artery dissection, precise causes are poorly understood. Significant differences between spontaneous internal carotid artery disse...
Source: Journal of Vascular Surgery - December 27, 2013 Category: Surgery Authors: M. von Babo, G.M. De Marchis, H. Sarikaya Tags: Abstracts Source Type: research

Characteristics and Outcomes of Patients With Multiple Cervical Artery Dissection Clinical Sciences
Conclusions— In the largest published series of patients with CeAD, we highlighted significant differences between multiple and single artery involvement. Features suggestive of an underlying vasculopathy (fibromuscular dysplasia) and environmental triggers (recent infection, cervical manipulation, and a remote history of head or neck surgery) were preferentially associated with multiple CeAD.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Bejot, Y., Aboa-Eboule, C., Debette, S., Pezzini, A., Tatlisumak, T., Engelter, S., Grond-Ginsbach, C., Touze, E., Sessa, M., Metso, T., Metso, A., Kloss, M., Caso, V., Dallongeville, J., Lyrer, P., Leys, D., Giroud, M., Pandolfo, M., Abboud, S., on behal Tags: Carotid and Vertebral A. Dissection Clinical Sciences Source Type: research

Endovascular treatment of acute carotid occlusion
Conclusions: Revascularization of the cervical carotid occlusion prior to treatment of the intracranial occlusion led to increased rates of recanalization in patients with tandem extracranial and intracranial occlusions. Whether a clinical benefit can be consistently derived likely relies on other factors, including the evaluation of cerebral perfusion.
Source: Clinical Neurology and Neurosurgery - November 18, 2013 Category: Neurosurgery Authors: L. Ratanaprasatporn, J.A. Grossberg, H.S. Spader, M.V. Jayaraman Tags: Original articles Source Type: research

Results of carotid artery stenting with transcervical access
Conclusions: CAS with the transcervical approach is a safe procedure with low incidence of stroke and complications. It can be used as an alternative to femoral access in patients with unfavorable aortoiliac or aortic arch anatomy.
Source: Journal of Vascular Surgery - September 26, 2013 Category: Surgery Authors: George S. Sfyroeras, Konstantinos G. Moulakakis, Fotis Markatis, Constantinos N. Antonopoulos, George A. Antoniou, John D. Kakisis, Elias N. Brountzos, Christos D. Liapis Tags: Review article Source Type: research

Styloid and Hyoid Bone Proximity Is a Risk Factor for Cervical Carotid Artery Dissection Clinical Sciences
Conclusions— Shorter distances between the styloid and ICA (and possibly also the hyoid and the ICA) are important risk factors for CAD. Further study is needed to determine whether dissections result from direct injury to the outer vessel wall of the carotid artery.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Renard, D., Azakri, S., Arquizan, C., Swinnen, B., Labauge, P., Thijs, V. Tags: Heparin, Coumarins, CT and MRI, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Reversible cerebral vasoconstriction syndrome and cervical artery dissection in 20 patients
Conclusion: The association of RCVS and CeAD was found in 12% of our patients with RCVS and 7% of our patients with CeAD. Underlying mechanisms are unknown. In practice, our results point to the need for a systematic study of both cervical and intracranial arteries in the 2 conditions.
Source: Neurology - August 26, 2013 Category: Neurology Authors: Mawet, J., Boukobza, M., Franc, J., Sarov, M., Arnold, M., Bousser, M.-G., Ducros, A. Tags: Secondary headache disorders, Stroke in young adults, Carotid artery dissection, Subarachnoid hemorrhage ARTICLE Source Type: research

Etiology of first‐ever ischaemic stroke in European young adults: the 15 cities young stroke study
ConclusionsThe etiology of IS in young adults has clear gender‐specific patterns that change with age. A notable portion of these patients remains without an evident stroke mechanism according to TOAST criteria.
Source: European Journal of Neurology - July 10, 2013 Category: Neurology Authors: N. Yesilot Barlas, J. Putaala, U. Waje‐Andreassen, S. Vassilopoulou, K. Nardi, C. Odier, G. Hofgart, S. Engelter, A. Burow, L. Mihalka, M. Kloss, J. Ferrari, R. Lemmens, O. Coban, E. Haapaniemi, N. Maaijwee, L. Rutten‐Jacobs, A. Bersano, C. Cereda, P. Tags: Original Article Source Type: research

Elevated peripheral leukocyte counts in acute cervical artery dissection
ConclusionsAcute CeAD was associated with particularly high WBC counts. Leukocytosis may reflect a pre‐existing inflammatory state, supporting the link between inflammation and CeAD.
Source: European Journal of Neurology - June 12, 2013 Category: Neurology Authors: C. Grond‐Ginsbach, A. Giossi, S. S. Aksay, S. T. Engelter, P. A. Lyrer, T. M. Metso, A. J. Metso, T. Tatlisumak, S. Debette, D. Leys, V. Thijs, A. Bersano, S. Abboud, M. Kloss, C. Lichy, A. Grau, A. Pezzini, E. Touzé, Tags: Original Article Source Type: research

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