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Comparing Cardiovascular Outcomes and Costs of Perindopril-, Enalapril- or Losartan-Based Antihypertensive Regimens in South Africa: Real-World Medical Claims Database Analysis
CONCLUSION: In South African individuals with private health insurance, a perindopril-based antihypertensive regimen provided better clinical and cost outcomes compared with other regimens.PMID:37730949 | DOI:10.1007/s12325-023-02641-8
Source: Adv Data - September 21, 2023 Category: Epidemiology Authors: Jacques R Snyman Freedom Gumedze Erika S W Jones Olufunke A Alaba Nqoba Tsabedze Alykhan Vira Ntobeko A B Ntusi Source Type: research

Metformin adherence and the risk of cardiovascular disease: a population-based cohort study
CONCLUSIONS: This study revealed that metformin adherence in patients with T2DM who required a first-line treatment may reduce the risk of subsequent CVD. Despite the availability of numerous novel antiglycemic agents, metformin adherence by patients who require a combination of antiglycemic agents provides an additional benefit of CVD protection.PMID:37051071 | PMC:PMC10084537 | DOI:10.1177/20406223231163115
Source: Adv Data - April 13, 2023 Category: Epidemiology Authors: Shun-Fan Yu Chien-Tai Hong Wan-Ting Chen Lung Chan Li-Nien Chien Source Type: research

Depression Risk in Post-stroke Aphasia Patients: A Nationwide Population-Based Cohort Study
Conclusion: Patients with PSA are at an increased risk of developing depression regardless of sex or stroke type.
Source: Neuroepidemiology - March 27, 2023 Category: Epidemiology Source Type: research

Real-World Racial Variation in Treatment and Outcomes Among Patients with Peripheral Artery Disease
CONCLUSIONS: Results of this real-world study suggest that Black patients with PAD have higher disease severity at the time of diagnosis and are at increased risk of experiencing adverse outcomes following diagnosis.PMID:36877443 | DOI:10.1007/s12325-023-02465-6
Source: Adv Data - March 6, 2023 Category: Epidemiology Authors: Keith C Ferdinand Kay Sadik Richard Browne Urvi Desai Patrick Lefebvre Dominique Lejeune Malena Mahendran Fran çois Laliberté Lisa Matay David G Armstrong Source Type: research

Cardiovascular risk associated with allopurinol or benzbromarone treatment in patients with gout
CONCLUSION: In this study, significant difference was not found in CV risk between allopurinol and benzbromarone initiators. In the high-CV-risk group, the incidence of CV events did not differ between allopurinol and benzbromarone initiators.PMID:35966182 | PMC:PMC9373176 | DOI:10.1177/1759720X221116409
Source: Adv Data - August 15, 2022 Category: Epidemiology Authors: Yeonghee Eun Heewon Han Kyunga Kim Seonyoung Kang Seulkee Lee Hyungjin Kim Jaejoon Lee Eun-Mi Koh Hoon-Suk Cha Source Type: research

Hospitalisation rate and mortality among people with and without diabetes during the COVID-19 pandemic year 2020
AbstractMost studies reported reduced health care use among people with diabetes during the COVID-19 pandemic. This may be due to restricted medical services or people avoiding health care services because they fear being infected with COVID-19 in health care facilities. The aim of our study was to analyse hospitalisation and mortality in people with and without diabetes in Germany during the COVID-19 pandemic year 2020 compared to 2017 –2019. The data were sourced from a German statutory health insurance company covering 3.2 million people. We estimated age-sex standardised rates of mortality, all-cause hospitalisation,...
Source: European Journal of Epidemiology - June 8, 2022 Category: Epidemiology Source Type: research

Hobby engagement and risk of disabling dementia
CONCLUSIONS: Hobby engagement in both mid-life and late-life was associated with a lower risk of disabling dementia without a history of stroke.PMID:35569953 | DOI:10.2188/jea.JE20210489
Source: Journal of Epidemiology - May 15, 2022 Category: Epidemiology Authors: Takumi Matsumura Isao Muraki Ai Ikeda Kazumasa Yamagishi Kokoro Shirai Nobufumi Yasuda Norie Sawada Manami Inoue Hiroyasu Iso Eric J Brunner Shoichiro Tsugane Source Type: research

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