Filtered By:
Education: Lessons
Vaccination: Vaccines
This page shows you your search results in order of date.
Order by Relevance | Date
Total 817 results found since Jan 2013.
Control groups for HIV prevention efficacy trials: what does the future hold?
Curr Opin HIV AIDS. 2023 Sep 12. doi: 10.1097/COH.0000000000000818. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Ending the HIV epidemic will require the development of additional effective immune-mediated and nonimmune-mediated means of HIV prevention. Evaluating novel interventions requires large, controlled trials demonstrating efficacy. Recent advances in the field of HIV prevention necessitate new approaches to efficacy trial design.RECENT FINDINGS: Three classes of efficacy trial designs are possible: standard of prevention-controlled trials, active-controlled trials, and active-controlled trials augmented with e...
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Holly Janes Susan Buchbinder Source Type: research
An update on one-dose HPV vaccine studies, immunobridging and humoral immune responses - A meeting report
This report summarises the discussions and lessons learned on two topics: an update on one-dose HPV vaccination studies and humoral immune responses upon HPV vaccination. Long-term follow-up studies from Costa Rica (eleven years) and India (ten years) report stable levels of antibodies after a single HPV vaccination. High vaccine effectiveness against incident persistent HPV 16/18 infection was seen in India (95.4%, 85.0-99.9) ten years postvaccination and in Kenya (97.5%, 81.7-99.7) eighteen months postvaccination, an important observation in a setting with a higher HPV prevalence. The potential impact of HPV vaccination ...
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Dur-E-Nayab Waheed F Ricardo Burdier Carina Eklund Iacopo Baussano Filipe Cola ço Mariz Laura T éblick Nelly Mugo Deborah Watson-Jones Margaret Stanley Marc Baay Alex Vorsters Source Type: research
Canada's National Advisory Committee on immunization: Adaptations and challenges during the COVID-19 pandemic
Vaccine. 2023 Aug 30:S0264-410X(23)00991-X. doi: 10.1016/j.vaccine.2023.08.048. Online ahead of print.ABSTRACTThe COVID-19 pandemic has challenged traditional vaccine guidance infrastructure and frameworks, and added urgency and complexity to the operation of National Immunization Technical Advisory Groups (NITAGs). Canada's National Advisory Committee on Immunization (NACI) provides immunization guidance to the Public Health Agency of Canada (PHAC) who publicly shares expert and evidence-informed guidance with Canadian provinces and territories. Throughout the pandemic, NACI and PHAC implemented many adaptations to meet u...
Source: Vaccine - September 1, 2023 Category: Allergy & Immunology Authors: Matthew Tunis Shelley Deeks Robyn Harrison Caroline Quach Shainoor Ismail Marina Salvadori Bryna Warshawsky Kelsey Young Christine Mauviel Erin Henry Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
T cell control of SARS-CoV-2: When, which, and where?
Semin Immunol. 2023 Aug 29;70:101828. doi: 10.1016/j.smim.2023.101828. Online ahead of print.ABSTRACTEfficient immune protection against viruses such as SARS-CoV-2 requires the coordinated activity of innate immunity, B and T cells. Accumulating data point to a critical role for T cells not only in the clearance of established infection, but also for aborting viral replication independently of humoral immunity. Here we review the evidence supporting the contribution of antiviral T cells and consider which of their qualitative features favour efficient control of infection. We highlight how studies of SARS-CoV-2 and other c...
Source: Seminars in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Mariana O Diniz Mala K Maini Leo Swadling Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
T cell control of SARS-CoV-2: When, which, and where?
Semin Immunol. 2023 Aug 29;70:101828. doi: 10.1016/j.smim.2023.101828. Online ahead of print.ABSTRACTEfficient immune protection against viruses such as SARS-CoV-2 requires the coordinated activity of innate immunity, B and T cells. Accumulating data point to a critical role for T cells not only in the clearance of established infection, but also for aborting viral replication independently of humoral immunity. Here we review the evidence supporting the contribution of antiviral T cells and consider which of their qualitative features favour efficient control of infection. We highlight how studies of SARS-CoV-2 and other c...
Source: Seminars in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Mariana O Diniz Mala K Maini Leo Swadling Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
