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Drug: Melatonin
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Total 52 results found since Jan 2013.

Paediatric sepsis-associated encephalopathy (SAE): a comprehensive review
Mol Med. 2023 Feb 23;29(1):27. doi: 10.1186/s10020-023-00621-w.ABSTRACTSepsis-associated encephalopathy (SAE) is one of the most common types of organ dysfunction without overt central nervous system (CNS) infection. It is associated with higher mortality, low quality of life, and long-term neurological sequelae, its mortality in patients diagnosed with sepsis, progressing to SAE, is 9% to 76%. The pathophysiology of SAE is still unknown, but its mechanisms are well elaborated, including oxidative stress, increased cytokines and proinflammatory factors levels, disturbances in the cerebral circulation, changes in blood-brai...
Source: Molecular Medicine - February 24, 2023 Category: Molecular Biology Authors: John Sieh Dumbuya Siqi Li Lili Liang Qiyi Zeng Source Type: research

Exogenous melatonin promotes the growth of alfalfa (Medicago sativa L.) under NaCl stress through multiple pathways
Ecotoxicol Environ Saf. 2022 Aug 1;242:113938. doi: 10.1016/j.ecoenv.2022.113938. Online ahead of print.ABSTRACTSalinity is one of the most common factors affecting alfalfa (Medicago sativa L.), and NaCl is one of the main factors of salinity stress which can cause heavy losses in agricultural production in the world. The application of exogenous melatonin (MT) plays a major role in numerous plants against various stress environments. The effects of exogenous MT on the NaCl tolerance of alfalfa treated with the control, 100 µmol L-1 MT, 150 mmol L-1 NaCl, or 150 mmol L-1 NaCl+ 100 µmol L-1 MT were investigated. The resul...
Source: Ecotoxicology and Environmental Safety - August 4, 2022 Category: Environmental Health Authors: Junpeng Niu Zhao Chen Zhipeng Guo Nan Xu Xin Sui Momi Roy Hafiz Abdul Kareem Mahmood Ul Hassan Jian Cui Quanzhen Wang Source Type: research

The Effects of Vitamin Therapy on ASD and ADHD: A Narrative review
CNS Neurol Disord Drug Targets. 2022 May 17. doi: 10.2174/1871527321666220517205813. Online ahead of print.ABSTRACTThe effects of a sufficient amounts of vitamins and nutrients on the proper function of the nervous system have always been regarded by scientists. In recent years, there are many studies have been done on controling or improving the symptoms of neurological and behavioral disorders which is created by changes in the level of vitamins and other nutrition, such as omega-3 and iron supplements. Autism spectrum disorder (ASD) is a neurodevelopmental disorder that causes disruption individual communication, especi...
Source: CNS and Neurological Disorders Drug Targets - May 19, 2022 Category: Drugs & Pharmacology Authors: Mohadeseh Poudineh Sadaf Parvin Mehrnia Omidali Farhad Nikzad Fatemeh Mohammadyari Fatemeh Sadeghi Poor Ranjbar Fayaz Rasouli Sepehr Nanbakhsh Sepehr Olangian-Tehrani Source Type: research

Hormesis and neural stem cells
Free Radic Biol Med. 2021 Dec 3:S0891-5849(21)00854-6. doi: 10.1016/j.freeradbiomed.2021.12.003. Online ahead of print.ABSTRACTThis paper provides a detailed identification and assessment of hormetic dose responses in neural stem cells (NSCs) as identified in a number of animal models and human tissues, with particular emphasis on cell proliferation and differentiation. Hormetic dose responses were commonly observed following administration of a number of agents, including dietary supplements [e.g., berberine, curcumin, (-)-epigallocatechin-3-gallate (EGCG), Ginkgo Biloba, resveratrol], pharmaceuticals (e.g., lithium, lova...
Source: Free Radical Biology and Medicine - December 6, 2021 Category: Biology Authors: Edward J Calabrese Vittorio Calabrese Gaurav Dhawan Rachna Kapoor James Giordano Source Type: research