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Interaction of night shift work with polymorphism in melatonin receptor 1B gene on incident stroke
Conclusions These results suggest that MTNR1B rs10830963 may potentially modify the associations between night shift work and incident stroke. by Chen Y, Yang L, Liang Y, He Z, Ai Q-YH, Chen W, Xue H, Zhou M, Wang Y, Ma H, Geng Q. doi:10.5271/sjweh.4022
Source: Scandinavian Journal of Work, Environment and Health - March 28, 2022 Category: Occupational Health Tags: Original article Source Type: research

Pineal Calcification Is Associated with Symptomatic Cerebral Infarction
Conclusions: Pineal calcification may be a potential new contributor to cerebral infarction.
Source: Journal of Stroke and Cerebrovascular Diseases - February 22, 2013 Category: Neurology Authors: Amnat Kitkhuandee, Kittisak Sawanyawisuth, Nutjaree Pratheepawanit Johns, Jaturat Kanpittaya, Jeffrey Johns Tags: Original Articles Source Type: research

Cryptotanshinone Attenuates Oxygen-Glucose Deprivation/ Recovery-Induced Injury in an in vitro Model of Neurovascular Unit
Conclusions Despite the above limitations, we indicate that the protective mechanism of CTs against OGD/R damage might exert via inhibiting neuron apoptosis and attenuating BBB disruption. Furthermore, we also clarified that CTs inhibited neuronal apoptosis possibly by blocking the activation of MAPK signaling pathways, and CTs alleviating BBB disruption may associated with the regulation of TJPs and MMP-9 in our experiment. Accordingly, CTs will represent a novel and potent candidate for the treatment of CIRI in the future. Ethics Statement This study was carried out in accordance with the recommendations of China�...
Source: Frontiers in Neurology - April 17, 2019 Category: Neurology Source Type: research

Mortality of Shift Workers
This study strengthens the evidence of a connection between shift work and all-cause mortality. It also provides support for an association between shift work and mortality of cardiovascular disease. The mechanisms responsible for the association between shift work and disease are probably co mplex and influenced by genetics, lifestyle, sleep, social stress, and disturbed circadian rhythms (7). Further epidemiological studies and experimental studies are needed to explain the causal pathways. One issue would be to find a better variable measuring the circadian phase. Shift work is not a valid proxy since previous studies...
Source: Scandinavian Journal of Work, Environment and Health - January 25, 2017 Category: Occupational Health Tags: Editorial Source Type: research

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