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Infectious Disease: Coronavirus
Drug: Magnesium

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Total 102 results found since Jan 2013.

Mechanistic Insight into the role of Vitamin D and Zinc in Modulating Immunity Against COVID-19: A View from an Immunological Standpoint
Biol Trace Elem Res. 2023 Mar 9:1-15. doi: 10.1007/s12011-023-03620-4. Online ahead of print.ABSTRACTThe pathophysiology of coronavirus disease-19 (COVID-19) is characterized by worsened inflammation because of weakened immunity, causing the infiltration of immune cells, followed by necrosis. Consequently, these pathophysiological changes may lead to a life-threatening decline in perfusion due to hyperplasia of the lungs, instigating severe pneumonia, and causing fatalities. Additionally, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause mortality due to viral septic shock, resulting from unr...
Source: Biological Trace Element Research - March 8, 2023 Category: Biology Authors: Nuzhat Ahsan Mohammad Imran Yousuf Mohammed Fatme Al Anouti Mohammad Idreesh Khan Tanushree Banerjee Mohd Adnan Fauzia Ashfaq Marek Kieliszek Syed Amir Ashraf Afrozul Haq Source Type: research

Proton pump inhibitors: Understanding the associated risks and benefits of long-term use
CONCLUSION: Higher-quality data is needed to better understand PPI-associated risks of the adverse effects listed above. Until then, clinicians may consider greater vigilance with PPI use; however, the data does not demonstrate a need for wide adoption of de-escalation strategies solely out of safety concerns.PMID:36629265 | DOI:10.1093/ajhp/zxad009
Source: American Journal of Health-System Pharmacy : AJHP - January 11, 2023 Category: Drugs & Pharmacology Authors: Kristina M Thurber Ashley O Otto Shawna L Stricker Source Type: research

Piezoelectric biosensors and nanomaterials-based therapeutics for coronavirus and other viruses: A Mini-review
Curr Top Med Chem. 2022 Dec 26. doi: 10.2174/1568026623666221226091907. Online ahead of print.ABSTRACTSince late 2019, the novel coronavirus (COVID-19) pandemic has caused considerable mortality worldwide. This pandemic raised concerns and provoked research on the diagnosis and treatment of viruses-based diseases. The accurate diagnosis of a virus requires high specificity and sensitivity. Piezoelectric sensors are analytical devices that work on mass-sensitivity-based micromechanical transducers. The change in the mass by the interaction between biological elements and the frequency is recorded by measuring the alternate ...
Source: Current Topics in Medicinal Chemistry - December 27, 2022 Category: Chemistry Authors: Madeshwaran Sekkarapatti Ramasamy Rakesh Bhaskar Sung Soon Han Source Type: research

Therapeutic potential of metal ions for COVID-19: insights from the papain-like protease of SARS-CoV-2
Biochem J. 2022 Oct 7:BCJ20220380. doi: 10.1042/BCJ20220380. Online ahead of print.ABSTRACTCoronaviruses have been responsible for multiple challenging global pandemics, including coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Papain-like protease (PLpro), one of two cysteine proteases responsible for the maturation and infectivity of SARS-CoV-2, processes and liberates functional proteins from the viral polyproteins and cleaves ubiquitin and ISG15 modifications to inhibit innate immune sensing. Consequently, PLpro is an attractive target for developing...
Source: The Biochemical Journal - October 7, 2022 Category: Biochemistry Authors: Cameron Lee Shetler Juliana C Ferreira Thyago H S Cardoso Edson M A Silva Nitin K Saksena Wael M Rabeh Source Type: research

The National COVID-19 Clinical Evidence Taskforce: pregnancy and perinatal guidelines
Med J Aust. 2022 Oct 2. doi: 10.5694/mja2.51729. Online ahead of print.ABSTRACTINTRODUCTION: Pregnant women are at higher risk of severe illness from coronavirus disease 2019 (COVID-19) than non-pregnant women of a similar age. Early in the COVID-19 pandemic, it was clear that evidenced-based guidance was needed, and that it would need to be updated rapidly. The National COVID-19 Clinical Evidence Taskforce provided a resource to guide care for people with COVID-19, including during pregnancy. Care for pregnant and breastfeeding women and their babies was included as a priority when the Taskforce was set up, with a Pregnan...
Source: Med J Aust - October 2, 2022 Category: General Medicine Authors: Caroline Se Homer Vijay Roach Leila Cusack Michelle L Giles Clare Whitehead Wendy Burton Teena Downton Glenda Gleeson Adrienne Gordon Karen Hose Jenny Hunt Jackie Kitschke Nolan McDonnell Philippa Middleton Jeremy Jn Oats Antonia W Shand Kellie Wilton Jos Source Type: research