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Drug: Magnesium
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Total 8 results found since Jan 2013.

Hidden hydrogen: Earth may hold vast stores of a renewable, carbon-free fuel
IN THE SHADE of a mango tree, Mamadou Ngulo Konaré recounted the legendary event of his childhood. In 1987, well diggers had come to his village of Bourakébougou, Mali, to drill for water, but had given up on one dry borehole at a depth of 108 meters. “Meanwhile, wind was coming out of the hole,” Konaré told Denis Brière, a petrophysicist and vice president at Chapman Petroleum Engineering, in 2012. When one driller peered into the hole while smoking a cigarette, the wind exploded in his face. “He didn’t die, but he was burned,” Konaré continued. “And now we had a huge fire. The color of the fire...
Source: ScienceNOW - February 16, 2023 Category: Science Source Type: news

Magnesium Homeostasis: Lessons from Human Genetics
Clin J Am Soc Nephrol. 2023 Feb 1. doi: 10.2215/CJN.0000000000000103. Online ahead of print.ABSTRACTMg2+, the fourth most abundant cation in the body, serves as a co-factor for about 600 cellular enzymes. One third of ingested Mg2+ is absorbed from the gut through a saturable transcellular process and a concentration-dependent paracellular process. Absorbed Mg2+ is excreted by the kidney and maintains serum Mg2+ within a narrow range of 0.7 to 1.25 mmol/L. The reabsorption of Mg2+ by the nephron is characterized by paracellular transport in the proximal tubule and thick ascending limb. The nature of the transport pathways ...
Source: Clinical Journal of the American Society of Nephrology : CJASN - February 1, 2023 Category: Urology & Nephrology Authors: Aubrey R Morrison Source Type: research

Challenges of the newer generation of Resorbable magnesium scaffolds: Lessons from failure mechanisms of the past generation
J Cardiol. 2022 Sep 16:S0914-5087(22)00226-X. doi: 10.1016/j.jjcc.2022.09.003. Online ahead of print.ABSTRACTBioresorbable scaffolds (BRS) were developed to overcome the obstacles of metallic stents, mostly related to sustained presence of metallic foreign body in the coronary vessel. Following earlier success of single-arm BRS studies, randomized controlled trials of Absorb bioresorbable vascular scaffold (Abbott Vascular, Santa Clara, CA, USA) showed poor long-term clinical outcomes, particularly in terms of scaffold thrombosis. BRS made from magnesium alloy provide a promising alternative in terms of radial force, strut...
Source: Journal of Cardiology - September 19, 2022 Category: Cardiology Authors: Masaru Seguchi Alp Aytekin Tobias Lenz Philipp Nicol Hector A Alvarez-Covarrubias Erion Xhepa Grace R Klosterman Alicia Beele Emina Sabic L éa Utsch Aseel Alyaqoob Michael Joner Source Type: research

LITFL Review – Best of 2015
Welcome to the Best of 2015 LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chuck of FOAM. The Most Fair Dinkum Ripper Beauts of the Year SMACC Podcast: Crack the Chest Get Crucified (John Hinds) John’s talk from the opening plenary at SMACC Chicago had a furious battle with David Newman’s talk for the number one spot. Both were clear front runners given the shear numb...
Source: Life in the Fast Lane - January 8, 2016 Category: Emergency Medicine Authors: Anand Swaminathan Tags: Education LITFL review Source Type: blogs

Quick magnesium treatment fails to improve stroke outcomes, but study has silver lining
In the first study of its kind, a consortium led by UCLA physicians found that giving stroke patients intravenous magnesium within an hour of the onset of symptoms does not improve stroke outcomes.   However, the 8-year trial did find that with the help of paramedics in the field, intravenous medications can frequently be administered to stroke victims within that so-called "golden hour," during which they have the best chance to survive and avoid debilitating, long-term neurological damage.   The latter finding is a "game-changer," said Dr. Jeffrey Saver, director of the UCLA Stroke Center and a professor of ...
Source: UCLA Newsroom: Health Sciences - February 13, 2014 Category: Universities & Medical Training Source Type: news