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Should intravenous acetaminophen be considered for post craniotomy pain management? A Meta-analysis of randomized controlled trials
CONCLUSIONS: This meta-analysis provides class one evidence that IV Acetaminophen can significantly reduce postoperative pain in craniotomy patients with an excellent safety profile; however, there are not benefits in terms of hospital stay, opioid requirement, or patients' satisfaction.PMID:34647710 | DOI:10.23736/S0390-5616.21.05402-3
Source: Journal of Neurosurgical Sciences - October 14, 2021 Category: Neurosurgery Authors: Mahmoud A Ebada Ahmed S Ali Abdelrahman Elshakankiry Tarek Essa Ahmad Khater Mohamed Hossam Hieder Al-Shami Eshak I Bahbah Hazem S Ghaith Ulrick S Kanmounye Ahmed Negida Source Type: research
Plasmapheresis, Rituximab, and Ceftriaxone Provided Lasting Improvement for a 27-Year-Old Adult Male with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)
We present a case report of a 27-year-old male patient who had lasting improvement with plasmapheresis, rituximab, and ceftriaxone. Our patient first developed sudden psychosis and confusion after GAS infections at age 17. He had elevated anti-streptolysin O (ASO) titers, negative urine drug screen, no ETOH in blood, normal CBC, normal TSH, normal salicylate, normal acetaminophen, and a normal head CT. The tentative diagnosis of PANDAS was made, and the patient was thereafter treated with antipsychotics, antibiotics, tonsillectomy, and IVIG which resulted in remissions and relapses of his neuropsychiatric symptoms. Once he...
Source: Case Reports in Psychiatry - November 12, 2021 Category: Psychiatry Authors: Adam Krouse Huihua Li Joseph A Krenzer William Nicholas Rose Source Type: research
Should intravenous acetaminophen be considered for post craniotomy pain management? A Meta-analysis of randomized controlled trials
CONCLUSIONS: This meta-analysis provides class one evidence that IV Acetaminophen can significantly reduce postoperative pain in craniotomy patients with an excellent safety profile; however, there are not benefits in terms of hospital stay, opioid requirement, or patients' satisfaction.PMID:34647710 | DOI:10.23736/S0390-5616.21.05402-3
Source: Journal of Neurosurgical Sciences - October 14, 2021 Category: Neurosurgery Authors: Mahmoud A Ebada Ahmed S Ali Abdelrahman Elshakankiry Tarek Essa Ahmad Khater Mohamed Hossam Hieder Al-Shami Eshak I Bahbah Hazem S Ghaith Ulrick S Kanmounye Ahmed Negida Source Type: research
Plasmapheresis, Rituximab, and Ceftriaxone Provided Lasting Improvement for a 27-Year-Old Adult Male with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)
We present a case report of a 27-year-old male patient who had lasting improvement with plasmapheresis, rituximab, and ceftriaxone. Our patient first developed sudden psychosis and confusion after GAS infections at age 17. He had elevated anti-streptolysin O (ASO) titers, negative urine drug screen, no ETOH in blood, normal CBC, normal TSH, normal salicylate, normal acetaminophen, and a normal head CT. The tentative diagnosis of PANDAS was made, and the patient was thereafter treated with antipsychotics, antibiotics, tonsillectomy, and IVIG which resulted in remissions and relapses of his neuropsychiatric symptoms. Once he...
Source: Case Reports in Psychiatry - November 12, 2021 Category: Psychiatry Authors: Adam Krouse Huihua Li Joseph A Krenzer William Nicholas Rose Source Type: research
Standing Intravenous Acetaminophen Is Associated With a Reduction of Post-operative Opioid Use in Infants Aged Less Than 1 Year Treated on the Acute Care Floor
Given the negative clinical effects opiates can have, the search for alternative forms of analgesia to treat post-operative pain continues. We implemented an opiate reduction strategy using standing intravenous (IV) acetaminophen for infants aged less than 1 y who underwent abdominal or anorectal surgery and recovered on the acute care floor.
Source: Journal of Surgical Research - April 9, 2022 Category: Surgery Authors: Rick D. Vavolizza, David F. Grabski, Zoe Roecker, Daniel Levin, Jonathan R. Swanson, Eugene D. McGahren, Jeffrey W. Gander Tags: Pediatric Surgery Source Type: research
Pharmacotherapy for Spine-Related Pain in Older Adults
AbstractAs the population ages, spine-related pain is increasingly common in older adults. While medications play an important role in pain management, their use has limitations in geriatric patients due to reduced liver and renal function, comorbid medical problems, and polypharmacy. This review will assess the evidence basis for medications used for spine-related pain in older adults, with a focus on drug metabolism and adverse drug reactions. A PubMed/OVID search crossing common spine, neck, and back pain terms with key words for older adults and geriatrics was combined with common drug classes and common drug names and...
Source: Drugs and Aging - June 27, 2022 Category: Geriatrics Source Type: research
Major areas of interest of artificial intelligence research applied to health care administrative data: a scoping review
Conclusions: The scoping review revealed the potential of AI application to health-related studies. However, several areas of interest in pharmacoepidemiology are sparsely reported, and the lack of details in studies related to pharmacotherapy suggests that AI could be used more optimally in pharmacoepidemiologic research.
Source: Frontiers in Pharmacology - July 18, 2022 Category: Drugs & Pharmacology Source Type: research
