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Total 324 results found since Jan 2013.

The association of diet-dependent acid load with colorectal cancer risk: a case-control study in Korea
We examined whether colorectal carcinogenesis is attributable to a diet with a high acid load. We recruited a total of 923 CRC cases and 1846 controls at the National Cancer Center in Korea for inclusion in a case-control study. We collected information on nutrient intake and specific clinical parameters of CRC by using a semiquantitative food frequency questionnaire and medical records, respectively. Potential renal acid load (PRAL) and net endogenous acid production (NEAP) were used to estimate diet-dependent acid load. We used an unconditional logistic regression model to analyse the association. Dietary acid load score...
Source: The British Journal of Nutrition - August 31, 2023 Category: Nutrition Authors: Tao Thi Tran Madhawa Gunathilake Jeonghee Lee Jae Hwan Oh Hee Jin Chang Dae Kyung Sohn Aesun Shin Jeongseon Kim Source Type: research

Effect of < em > Rhodiola rosea < /em > Rhizome and < em > Punica granatum < /em > Fruit Peel on the Metabolic Processes and Physiological Activity of Rats Fed with Excessively Fat Diet
CONCLUSIONS: Body mass of rats fed with golden root (R. rosea) reached 125.8 % of the initial body mass; when fed on pomegranate (P. granatum), it reached 123.9 %; and the control group reached only 111.5 % of the initial body mass. The rhizomes of R. rosea in the diet of male rats during the month of the experiment did not cause significant changes in the relative organ mass, and the pomegranate peel fruits led to a decrease in the thymus relative mass, as well as liver and brain. R. rosea rhizomes in the rats' diet led to an increase in the activity of alkaline phosphatase, and also to a decrease in the concentration of ...
Source: Atherosclerosis - July 17, 2023 Category: Cardiology Authors: Maryna Lieshchova Viktor Brygadyrenko Source Type: research

Longan extract suppresses food intake through regulation of POMC/AgRP neuronal activities and endoplasmic reticulum stress in hypothalamus of db/db mice
Front Nutr. 2023 Jun 21;10:1143613. doi: 10.3389/fnut.2023.1143613. eCollection 2023.ABSTRACTType 2 diabetes mellitus (T2DM) is one of the biggest public health issues worldwide and closely related to development of other chronic diseases such as cardiovascular diseases, cancer and neurodegenerative diseases. Considerable percentage of T2DM patients undergo have suffered from binge eating disorder which exacerbates insulin resistance and metabolic challenges. Longan (Dimocarpus longan L.) and its constituents are reported for their various health benefits. However, it is still unknown whether longan fruit supplementation c...
Source: Cancer Control - July 7, 2023 Category: Cancer & Oncology Authors: Hyeyoon Eo Seong Hye Kim In Gyoung Ju Eugene Huh Sinyeon Kim Jin Gyu Choi Se Woong Kim Miwon Son Myung Sook Oh Source Type: research

Modulatory role of Coriandrum sativum (coriander) extract against diabetic complications on the gonads of female rats and their offspring
Tissue Cell. 2023 Jun 9;83:102127. doi: 10.1016/j.tice.2023.102127. Online ahead of print.ABSTRACTIt is well known that diabetes is associated with impairment of ovarian and testicular structure and function. Coriander (Coriandrum sativum L.) is identified as one of the oldest herbal plants valued for its nutritional and medicinal properties. This work is mainly designed to evaluate the possible modulatory role of dry coriander fruit extract against gonadal impairments associated with diabetes in female rats and their pups. Twenty-four pregnant rats were divided into four groups (n = 6): group I served as control, group II...
Source: Tissue and Cell - June 18, 2023 Category: Cytology Authors: Amany Attaallah Asmaa R Elmrazeky Abd El-Fattah B M El-Beltagy Karoline K Abdelaziz Mona Fm Soliman Source Type: research

Isolation and antihyperglycemic effects of garcibractinols A-H, intricate polycyclic polyprenylated acylphloroglucinols from the fruits of Garcinia bracteata
Bioorg Chem. 2023 Jun 5;138:106651. doi: 10.1016/j.bioorg.2023.106651. Online ahead of print.ABSTRACTEight previously undescribed polycyclic polyprenylated acylphloroglucinols (PPAPs) were isolated from the fruits of Garcinia bracteata and named garcibractinols A-H. Garcibractinols A-F (compounds 1-6) were bicyclic polyprenylated acylphloroglucinols (BPAPs) sharing a rare bicyclo[4.3.1]decane core. On the other hand, garcibractinols G and H (compounds 7 and 8) shared an unprecedented BPAP skeleton bearing a 9-oxabicyclo[6.2.1]undecane core. The structures andabsolute configurations of compounds 1-8 were determined by spect...
Source: Bioorganic Chemistry - June 10, 2023 Category: Chemistry Authors: Xueni Li Qingqing Li Jing Xu Shuang Yang Xin Hu Zhengyang Lu Gui Mei Yu Chen Zhinan Mei Guangzhong Yang Source Type: research

Dietary sinensetin and polymethoxyflavonoids: Bioavailability and potential metabolic syndrome-related bioactivity
Crit Rev Food Sci Nutr. 2023 Jun 7:1-17. doi: 10.1080/10408398.2023.2219758. Online ahead of print.ABSTRACTSinensetin is among the most ubiquitous polyphenols in citrus fruit and recently has been extensively studied for its ability to prevent or treat diseases. The current literature on the bioavailability of sinensetin and its derivatives was reviewed and the potential ameliorative effects of metabolic syndrome in humans were evaluated. Sinensetin and its derivatives mainly aggregated in the large intestine and extensively metabolized through gut microbiota (GM) and the liver. So intestinal microorganisms had a significa...
Source: Atherosclerosis - June 7, 2023 Category: Cardiology Authors: Mutang Zhang Hao Jiang Shaobi Ou Min Qian Heming Qi Junping Chen Xiaofang Zeng Weidong Bai Gengsheng Xiao Source Type: research