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Infectious Disease: Influenza
Drug: Dexamethasone

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Total 22 results found since Jan 2013.

TWiV 978: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses co-detections of other respiratory viruses among children hospitalized with COVID-19, preprint review should form part of PhD programs and postdoc training, early and increased Influenza activity among children, COVID-19 vaccines versus pediatric hospitalization, SARS-CoV-2 variant-related abnormalities detected by prenatal MRI, protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the Omicron variant and severe disease, protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the omicron variant and severe dis...
Source: This Week in Virology - MP3 Edition - January 28, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Targeted delivery of an anti-inflammatory corticosteroid to Ly6C/G-positive cells abates severity of influenza A symptoms
Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2211065119. doi: 10.1073/pnas.2211065119. Epub 2022 Oct 17.ABSTRACTThe distribution of Ly6C/G-positive cells in response to an infection of the mouse respiratory tract with influenza A virus was followed noninvasively over time by immuno-positron emission tomography. We converted nanobodies that recognize Ly6C and Ly6G, markers of neutrophils and other myeloid cells, as well as an influenza hemagglutinin-specific nanobody, into 89Zr-labeled PEGylated positron emission tomography (PET) imaging agents. The PET images showed strong accumulation of these imaging agents in the lung...
Source: Cancer Control - October 17, 2022 Category: Cancer & Oncology Authors: Novalia Pishesha Thibault Harmand Claire Carpenet Xin Liu Atul Bhan Ashraful Islam Renate van den Doel William Pinney Hidde L Ploegh Source Type: research

Influenza A: H1N1 post-viral membranoproliferative glomerulonephritis occurring in aggressive systemic mastocytosis: Case report and literature review
Nephrol Ther. 2021 Oct 26:S1769-7255(21)00528-9. doi: 10.1016/j.nephro.2021.08.002. Online ahead of print.ABSTRACTSystemic mastocytosis is characterised by tissular infiltration and a cytokine storm due to mast cells excessive proliferation and activation. Herein, we report an extraordinary case of AH1N1 influenza post-viral glomerulonephritis occurring in the course of an aggressive systemic mastocytosis with an associated hematological neoplasm. Because of a multisystemic involvement including the liver and lungs, we treated mastocytosis with midostaurin (multiple inhibitor of kinase protein), anti H1/H2 blockers and dex...
Source: Nephrologie and Therapeutique - October 30, 2021 Category: Urology & Nephrology Authors: Quentin Bodard Patricia Rullier H élène Perrochia Moglie Le Quintrec M élissa Alamé Olivier Hermine Philippe Guilpain Alexandre Maria Source Type: research

The cytokine storms of COVID-19, H1N1 influenza, CRS and MAS compared. Can one sized treatment fit all?
Cytokine. 2021 May 26:155593. doi: 10.1016/j.cyto.2021.155593. Online ahead of print.ABSTRACTAn analysis of published data appertaining to the cytokine storms of COVID-19, H1N1 influenza, cytokine release syndrome (CRS), and macrophage activation syndrome (MAS) reveals many common immunological and biochemical abnormalities. These include evidence of a hyperactive coagulation system with elevated D-dimer and ferritin levels, disseminated intravascular coagulopathy (DIC) and microthrombi coupled with an activated and highly permeable vascular endothelium. Common immune abnormalities include progressive hypercytokinemia with...
Source: Cytokine - June 2, 2021 Category: Molecular Biology Authors: Gerwyn Morris Chiara C Bortolasci Basant K Puri Wolfgang Marx Adrienne O'Neil Eugene Athan Ken Walder Michael Berk Lisa Olive Andre F Carvalho Michael Maes Source Type: research

Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19
Brief Bioinform. 2021 May 1:bbab114. doi: 10.1093/bib/bbab114. Online ahead of print.ABSTRACTThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is undeniably the most severe global health emergency since the 1918 Influenza outbreak. Depending on its evolutionary trajectory, the virus is expected to establish itself as an endemic infectious respiratory disease exhibiting seasonal flare-ups. Therefore, despite the unprecedented rally to reach a vaccine that can offer widespread immunization, it is equally important to reach effective prevention and treatment regimens for coronavirus disease 2019 (COVID...
Source: Briefings in Bioinformatics - May 19, 2021 Category: Bioinformatics Authors: M Tomazou M M Bourdakou G Minadakis M Zachariou A Oulas E Karatzas E Loizidou A Kakouri C Christodoulou K Savva M Zanti A Onisiforou S Afxenti J Richter C G Christodoulou T Kyprianou G Kolios N Dietis G M Spyrou Source Type: research

Measures to cope with the COVID-19 pandemic in Germany: nonpharmaceutical and pharmaceutical interventions
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2021 Mar 31. doi: 10.1007/s00103-021-03306-z. Online ahead of print.ABSTRACTWhen the emerging novel SARS-CoV‑2 virus first appeared in December 2019, neither specific therapeutic options nor vaccinations were available. The role of nonpharmaceutical interventions (NPIs) became of central importance. At the Robert Koch Institute, a multilayer strategy consisting of population-based and individual preventive measures to control the pandemic was developed, which built upon existing influenza pandemic plans as well as generic plans. This paper explains the recomm...
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - March 31, 2021 Category: International Medicine & Public Health Authors: Ulrike Grote Mardjan Arvand Simon Brinkwirth Melanie Brunke Udo Buchholz Tim Eckmanns Max von Kleist Michaela Niebank Bettina Ruehe Kai Schulze Anna Stoliaroff-P épin Marc Thanheiser Lars Schaade Dunja Said Walter Haas Source Type: research