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Drug: Polyethylene Glycol

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Total 2716 results found since Jan 2013.

Targeted killing of CD133 < sup > + < /sup > lung cancer stem cells using paclitaxel-loaded PLGA-PEG nanoparticles with CD133 aptamers
CONCLUSION: CD133 aptamer can promote targeted delivery of paclitaxel to allow targeted killing of CD133+ lung CSCs. N-Pac-CD133 loaded with paclitaxel may provide an effective treatment for lung cancer by targeting the lung cancer stem cells.PMID:35249867 | PMC:PMC8901392 | DOI:10.12122/j.issn.1673-4254.2022.01.03
Source: Journal of Southern Medical University - March 7, 2022 Category: Universities & Medical Training Authors: L Pang X Huang L Zhu H Xiao M Li H Guan J Gao H Jin Source Type: research

Modifying Polydiacetylene Vesicle Compositions to Reduce Non-Specific Interactions
Macromol Res. 2021 Jul;29(7):449-452. doi: 10.1007/s13233-021-9059-7. Epub 2021 Jul 24.ABSTRACTPolydiacetylene (PDA) vesicles provide useful stimuli-responsive behavior as well as by the modular structure afford a means for the design of sensing and delivery systems with tunable target specificity. To reduce inherent non-specific interaction with either anionic or cationic formulations of polydiacetylene vesicles, we explored the use of various lengths of poly(ethylene glycol) (PEG) amphiphiles for integration and polymerization within PDA vesicles. Our results established that as little as 1% of polyethylene glycol amphip...
Source: Cell Research - March 24, 2022 Category: Cytology Authors: Gumaro Rojas Priyanka Shiveshwarkar Butaek Lim Anura Shrestha Izele Abure Anthony Nelson Justyn Jaworski Source Type: research

Targeted killing of CD133 < sup > + < /sup > lung cancer stem cells using paclitaxel-loaded PLGA-PEG nanoparticles with CD133 aptamers
CONCLUSION: CD133 aptamer can promote targeted delivery of paclitaxel to allow targeted killing of CD133+ lung CSCs. N-Pac-CD133 loaded with paclitaxel may provide an effective treatment for lung cancer by targeting the lung cancer stem cells.PMID:35249867 | PMC:PMC8901392 | DOI:10.12122/j.issn.1673-4254.2022.01.03
Source: Journal of Southern Medical University - March 7, 2022 Category: Universities & Medical Training Authors: L Pang X Huang L Zhu H Xiao M Li H Guan J Gao H Jin Source Type: research

Allergic Reactions to the COVID-19 vaccine (ARCOV) study: the McGill University Health Center (MUHC) experience
CONCLUSION: In this cohort of patients with a history of anaphylaxis and increased risk of allergic reactions to the COVID-19 vaccines, following allergist evaluation, including negative PEG skin testing, the vaccine was safely administered without any serious adverse events.PMID:35609744 | PMC:PMC9124043 | DOI:10.1016/j.anai.2022.05.014
Source: Annals of Allergy, Asthma and Immunology - May 24, 2022 Category: Allergy & Immunology Authors: Faisal ALMuhizi Michael Fein Sofianne Gabrielli Louise Gilbert Christos Tsoukas Moshe Ben-Shoshan Ana M Copaescu Ghislaine A C Isabwe Source Type: research

Assessment of two types of passive sampler for the efficient recovery of SARS-CoV-2 and other viruses from wastewater
In this study, we compared the virus-binding capacity of two passive samplers (cotton-based tampons and ion exchange filter papers) in two different water types (deionised water and wastewater). Here we focused on the capture of wastewater-associated viruses including Influenza A and B (Flu-A & B), SARS-CoV-2, human adenovirus (AdV), norovirus GII (NoVGII), measles virus (MeV), pepper mild mottle virus (PMMoV), the faecal marker crAssphage and the process control virus Pseudomonas virus phi6. After deployment, we evaluated four different methods to recover viruses from the passive samplers namely, (i) phosphate buffere...
Source: Adv Data - June 11, 2022 Category: Epidemiology Authors: Jessica L Kevill Kathryn Lambert-Slosarska Cameron Pellett Nick Woodhall India Richardson-O'Neill Igor P ântea Natasha Alex-Sanders Kata Farkas Davey L Jones Source Type: research