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Specialty: Geriatrics
Drug: Aspirin

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Total 23 results found since Jan 2013.

Effect of oral cilostazol on acute neurological deterioration and outcome of noncardioembolic minor stroke
Conclusion In noncardioembolic stroke, combined antithrombotic therapy with early oral cilostazol in the acute phase appears to be associated with a good outcome in patients with progressive stroke.
Source: Journal of Clinical Gerontology and Geriatrics - December 18, 2015 Category: Geriatrics Source Type: research

Effects of Antiplatelet Agents on Functional Outcome and Cognitive Status in Patients with Acute Ischemic Stroke
Conclusion The use of antiplatelet agents in acute ischemic stroke may have a favorable effect on functional outcome and cognitive status in patients at 3 months poststroke.
Source: International Journal of Gerontology - November 17, 2014 Category: Geriatrics Source Type: research

Controversies in antiplatelet therapy in the secondary prevention of stroke
Publication date: Available online 19 January 2016 Source:European Geriatric Medicine Author(s): T. Adamek Recurrence of stroke has been estimated at 3–4% yearly after TIA or stroke. There is no clear agreement in choosing antiplatelet therapy at this time. Europeans, Americans and British guidelines have been different. Aspirin is still used in secondary prevention of ischemic stroke, because of the longest experience with the best-achieved results in different studies and low price. Other used drugs are a combination of aspirin and dipyridamole, P2Y12 receptor antagonists – clopidogrel, ticlopidine, prasugrel an...
Source: European Geriatric Medicine - January 20, 2016 Category: Geriatrics Source Type: research

Comparing Cerebralcare Granule and aspirin for neurological dysfunction in acute stroke in real‐life practice
ConclusionsThis large‐scale, controlled trial indicated that CG may be a useful treatment in the management of post‐stroke patients.
Source: Psychogeriatrics - January 12, 2016 Category: Geriatrics Authors: Luqing Zhao, Lianming Liao, Fengyun Hu Tags: Original Article Source Type: research

Comparing Cerebralcare Granule and aspirin for neurological dysfunction in acute stroke in real ‐life practice
ConclusionsThis large‐scale, controlled trial indicated that CG may be a useful treatment in the management of post‐stroke patients.
Source: Psychogeriatrics - January 11, 2016 Category: Geriatrics Authors: Luqing Zhao, Lianming Liao, Fengyun Hu Tags: Original Article Source Type: research

Aspirin No Help for Stroke Outcomes (CME/CE)
(MedPage Today) -- Low-dose aspirin might help ward off transient ischemic attacks, but it didn't reduce overall incidence of stroke or improve outcomes following a stroke, an analysis of the Women's Health Study showed.
Source: MedPage Today Geriatrics - February 19, 2013 Category: Geriatrics Source Type: news

Acetylsalicylic acid non-responders after ischemic insult in geriatric patients.
CONCLUSION: It remains open whether the secondary prophylaxis or a more effective inhibition of platelet aggregation results in the improved protection against a future event. PMID: 24271142 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Gerontologie und Geriatrie - November 24, 2013 Category: Geriatrics Authors: Nosul M, Kolb GF Tags: Z Gerontol Geriatr Source Type: research

Effectiveness and safety of oral anticoagulants in older patients with atrial fibrillation: a systematic review and meta-regression analysis
Conclusionswarfarin use was superior to warfarin non-use, aspirin and no antithrombotic therapy in reducing the risk of stroke/TE in older AF patients, but with a possible increase in major bleeding. NOACs were superior to warfarin for stroke/TE prevention, with reduced risk of major bleeding.
Source: Age and Ageing - September 8, 2017 Category: Geriatrics Source Type: research

Antiplatelets and Vascular Dementia: A Systematic Review
J Aging Res. 2022 Sep 19;2022:9780067. doi: 10.1155/2022/9780067. eCollection 2022.ABSTRACTVascular dementia (VD) is a neurocognitive disorder whose precise definition is still up for debate. VD generally refers to dementia that is primarily caused by cerebrovascular disease or impaired cerebral blood flow. It is a subset of vascular cognitive impairment, a class of diseases that relate any cerebrovascular injury as a causal or correlating factor for cognitive decline, most commonly seen in the elderly. Patients who present with both cognitive impairment and clinical or radiologic indications of cerebrovascular pathology s...
Source: Journal of Aging Research - October 17, 2022 Category: Geriatrics Authors: Peter Alexander Shakthi Visagan Sara Jawhar Amogh Kare Noor Issa Reem Issa Abbas Jawhar Sneha Thomas Vasavi Gorantla Source Type: research

Efficacy and safety of apixaban compared with aspirin in the elderly: a subgroup analysis from the AVERROES trial
Conclusions: older patients with AF are at particularly high risk of stroke if given aspirin and have substantially greater relative and absolute benefits from apixaban compared with younger patients with no greater risk of haemorrhage. Clinical Trial Registration: ClinicalTrials.gov number: NCT00496769. URL: https://clinicaltrials.gov/ct2/show/NCT00496769.
Source: Age and Ageing - January 13, 2016 Category: Geriatrics Authors: Ng, K. H., Shestakovska, O., Connolly, S. J., Eikelboom, J. W., Avezum, A., Diaz, R., Lanas, F., Yusuf, S., Hart, R. G. Tags: Research Papers Source Type: research

Using an Atrial Fibrillation Decision Support Tool for Thromboprophylaxis in Atrial Fibrillation: Effect of Sex and Age
ConclusionPhysicians should understand that female sex is a significant risk factor for AF‐related stroke and incorporate this into decision‐making about thromboprophylaxis. Treating older adults with aspirin instead of OAT exposes them to significant risk of bleeding with little to no reduction in AF‐related stroke risk.
Source: Journal of the American Geriatrics Society - May 24, 2016 Category: Geriatrics Authors: Mark H. Eckman, Gregory Y.H. Lip, Ruth E. Wise, Barbara Speer, Megan Sullivan, Nita Walker, Brett Kissela, Matthew L. Flaherty, Dawn Kleindorfer, Peter Baker, Robert Ireton, Dave Hoskins, Brett M. Harnett, Carlos Aguilar, Anthony Leonard, Lora Arduser, Dy Tags: Clinical Investigations Source Type: research

Efficacy of Aspirin in the Primary Prevention of Cardiovascular Diseases and Cancer in the Elderly: A Population-Based Cohort Study in Korea
ConclusionAspirin reduced the risks of MACCE and cancer without increasing the bleeding risk in elderly Koreans with hypertension, T2DM, or dyslipidemia. Moreover, the benefits of the long-term use of aspirin in reducing the risks of MACCE were demonstrated. However, the decision of using aspirin for primary prevention must be carefully made on an individual basis, while estimating the benefit –risk balance of aspirin.
Source: Drugs and Aging - November 21, 2019 Category: Geriatrics Source Type: research

Impact of Fall Risk and Direct Oral Anticoagulant Treatment on Quality-Adjusted Life-Years in Older Adults with Atrial Fibrillation: A Markov Decision Analysis
ConclusionsOlder adults with atrial fibrillation benefit from stroke protection of anticoagulants, especially direct oral anticoagulants, even if they are at high risk of falls. Clinicians should not consider fall risk as a deciding factor for withholding anticoagulation in this population of patients.
Source: Drugs and Aging - July 8, 2021 Category: Geriatrics Source Type: research