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Reassessing Preterm Birth Prevention After the Withdrawal of 17- α Hydroxyprogesterone Caproate
Obstet Gynecol. 2023 Jul 13. doi: 10.1097/AOG.0000000000005290. Online ahead of print.ABSTRACTThe U.S. Food and Drug Administration has recently withdrawn approval for 17-α hydroxyprogesterone caproate for prevention of recurrent preterm birth, and recent studies have called into question benefits of the pessary in the setting of a short cervix. Obstetric health care professionals are once again left with limited remaining options for preterm birth prevention. This narrative review summarizes the best current evidence on the use of vaginal progesterone, low-dose aspirin, and cerclage for the prevention of preterm birth; a...
Source: Obstetrics and Gynecology - July 13, 2023 Category: OBGYN Authors: Kent Heyborne Source Type: research

Typical clinical presentation of acute myocardial infarction and confusing coronary angiography: A case report and literature review of coronary embolism
Medicine (Baltimore). 2023 May 12;102(19):e33782. doi: 10.1097/MD.0000000000033782.ABSTRACTRATIONALE: The purpose of this article is to discuss the characteristics, diagnosis, treatment, and outcomes of cases of multiple coronary embolism (CE) highly suspected to be caused by a dislodged aneurysm of the ventricular membranous septum (AVMS) thrombus.PATIENT CONCERNS: A 35-year-old man was rushed to the Chest Pain Center of Taicang TCM Hospital Affiliated to Nanjing University of Chinese Medicine for sudden onset of chest pain. The patient had severe and persistent chest pain without relief, accompanied by sweating throughou...
Source: Atherosclerosis - May 12, 2023 Category: Cardiology Authors: Mo-Qing Yin Li-Hua Fan Yun-Hu Chen Source Type: research

Fight Aging! Newsletter, August 8th 2022
In conclusion, aging research will benefit from a better definition of how specific regulators map onto age-dependent change, considered on a phenotype-by-phenotype basis. Resolving some of these key questions will shed more light on how tractable (or intractable) the biology of aging is. Does Acarbose Extend Life in Short Lived Species via Gut Microbiome Changes? https://www.fightaging.org/archives/2022/08/does-acarbose-extend-life-in-short-lived-species-via-gut-microbiome-changes/ Acarbose is one of a few diabetes medications shown to modestly slow aging in short-lived species. Researchers here take a ...
Source: Fight Aging! - August 7, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer
CONCLUSION: Adaptive stratified medicine platform studies are feasible in common cancers but present challenges. Our stakeholder feedback has helped to inform how these trial designs can succeed and answer multiple questions efficiently, providing resource is adequate.PMID:35083924 | DOI:10.1177/17407745211069879
Source: Clinical Trials - January 27, 2022 Category: Research Authors: Louise C Brown Janet Graham David Fisher Richard Adams Jenny Seligmann Matthew Seymour Richard Kaplan Emma Yates Mahesh Parmar Susan D Richman Philip Quirke Rachel Butler Kaikeen Shiu Gary Middleton Leslie Samuel Richard H Wilson Timothy S Maughan FOCUS4 Source Type: research

Fight Aging! Newsletter, August 30th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out mo...
Source: Fight Aging! - August 29, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Pandemic Fears: What the AIDS Battle Should Teach Us About COVID-19
By ANISH KOKA, MD As the globe faces a novel, highly transmissible, lethal virus, I am most struck by a medicine cabinet that is embarrassingly empty for doctors in this battle.  This means much of the debate centers on mitigation of spread of the virus.  Tempers flare over discussions on travel bans, social distancing, and self quarantines, yet the inescapable fact remains that the medical community can do little more than support the varying fractions of patients who progress from mild to severe and life threatening disease.  This isn’t meant to minimize the massive efforts brought to bear to keep pat...
Source: The Health Care Blog - March 12, 2020 Category: Consumer Health News Authors: Christina Liu Tags: CORVID-19 Health Policy Patients Physicians AIDS Anish Koka AZT coronavirus COVID-19 FDA novel coronavirus Pandemic Source Type: blogs

Why I am a Crusader in the Anti-Vaccine, Anti-Drug Movement
Conclusion The doctors gave my daughter drugs they knew would cause her kidneys to stop working. They gave her these drugs in spite of both of us telling them on a day-to-day basis not to give them. The hospital covered it up. The hospital refused to give us the incident report. The hospital refused to give us a copy of the notes from the meeting with the ethics committee. The hospital denied my daughter’s right to make her own decisions. The hospital tried to deny me from being my daughter's advocate. The hospital administrator threatened to charge me with practicing medicine without a license. The CEO refused to talk t...
Source: vactruth.com - September 11, 2015 Category: Allergy & Immunology Authors: Jim O'Kelly Tags: Case Reports on Vaccine Injury Human Jim O'Kelly Top Stories truth about vaccines Vaccine Death Source Type: blogs