Pandemic Fears: What the AIDS Battle Should Teach Us About COVID-19
By ANISH KOKA, MD As the globe faces a novel, highly transmissible, lethal virus, I am most struck by a medicine cabinet that is embarrassingly empty for doctors in this battle. This means much of the debate centers on mitigation of spread of the virus. Tempers flare over discussions on travel bans, social distancing, and self quarantines, yet the inescapable fact remains that the medical community can do little more than support the varying fractions of patients who progress from mild to severe and life threatening disease. This isn’t meant to minimize the massive efforts brought to bear to keep patients alive by health care workers but those massive efforts to support failing organs in the severely ill are in large part because we lack any effective therapy to combat the virus. It is akin to taking care of patients with bacterial infections in an era before antibiotics, or HIV/AIDS in an era before anti-retroviral therapy. It should be a familiar feeling for at least one of the leading physicians charged with managing the current crisis – Dr. Anthony Fauci. Dr. Fauci started as an immunologist at the NIH in the 1960s and quickly made breakthroughs in previously fatal diseases marked by an overactive immune response. Strange reports of a new disease that was sweeping through the gay community in the early 1980’s caused him to shift focus to join the great battle against the AIDS epidemic. ...
County commissioners told the Pittsburgh Business Times and other media outlets last week that they were told to expect targeted mitigation measures by Thursday.
Medical College of Wisconsin president and CEO Dr. John Raymond Sr. called “very troubling” the recent increase in new Covid-19 cases in Wisconsin, but said lagging indicators of the disease’s impact like hospitalizations and deaths are not alarming so far. The number of new diagnoses in Wisconsin jumped in recent days after a lull following the Fourth of July. Wisc onsin posted its four highest days for new cases from July 9 through Sunday ranging from 752 to 929. “Our early indicators…
An Austin company has created a device that can measure someone's heart beat without any physical contact. The race is on to bring the product to market as the world deals with the coronavirus pandemic. Click through to learn more about their latest partnership.
A biopharmaceutical company that has been working in collaboration with UAB on an intranasal Covid-19 vaccine candidate said preclinical studies of the candidate had positive results. Altimmune Inc., a Gaithersburg, Maryland-based firm, said the results showed strong neutralizing activity and potent immunity in the respiratory tract. The nasal injection in the respiratory tract may be necessary to block both infection and transmission of the virus and prevent further spread. Based on the findings,…
New J. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0NJ02844D, PaperMuhammad Khattab, Ahmed A. Al-Karmalawy Preclinical and clinical studies on Mebendazole revealed its potential as anticancer agent. We therefore aimed to investigate its binding interactions with one of the most important cancer targets (Tubulin protein)... The content of this RSS Feed (c) The Royal Society of Chemistry
New J. Chem., 2020, Advance Article DOI: 10.1039/D0NJ02175J, PaperPhanumas Yomthiangthae, Takeshi Kondo, Orawon Chailapakul, Weena Siangproh A simple and modification-free SPCE demonstrated high efficiency for the simultaneous detection of VB2, VB6, and VC in various practical applications. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
The mayor wants to avoid more restrictions on business, but that will depend on whether Covid-19 cases keep rising.
Cases rise by over 230,000 worldwide in 24 hours; 250,000 people in Manila to return to lockdown; Brazil cases near 2m‘Compelling’ evidence air pollution worsens coronavirus – studyGerman study finds low Covid-19 infection rate in schoolsFauci sidelined as Trump ’s White House steps up briefing campaignBereaved urge EU chief to supervise Italian coronavirus inquiry7.57pmBSTThe Trump administration is increasinglyat war with Anthony Fauci, the federal government ’s top public health expert, over the handling of the epidemic, as the US continues to report around 60,000 new cases a day.In what ap...
Mice that experienced heart attacks underwent a large-scale shift in their immune systems that allowed cancer to flourish, perhaps explaining the observation in patients.
Conclusion: So far no pharmacological intervention was proven effective and safe to warrant its use in the routine treatment of COVID-19 patients; therefore such patients should ideally be treated in the context of clinical trials. The recommendations herein provided will be revised continuously aiming to capture newly generated evidence.
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