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Nutrition: Vitamins
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Total 441 results found since Jan 2013.
Structure-function of DHEA binding proteins
Vitam Horm. 2023;123:587-617. doi: 10.1016/bs.vh.2022.12.002. Epub 2022 Dec 16.ABSTRACTDehydroepiandrosterone (3β-hydroxy-5-androsten-17-one, DHEA) and its sulfated metabolite DHEA-S are the most abundant circulating steroids and are precursors for active sex steroid hormones, estradiol and testosterone. DHEA has a broad range of reported effects in the central nervous system (CNS), cardiovascular system, adipose tissue, kidney, liver, and in the reproductive system. The mechanisms by which DHEA and DHEA-S initiate their biological effects are diverse. DHEA and DHEA-S may directly bind to plasma membrane (PM) receptors, i...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Barbara J Clark Carolyn M Klinge Source Type: research
Membrane estrogen receptor and follicle-stimulating hormone receptor
Vitam Horm. 2023;123:555-585. doi: 10.1016/bs.vh.2022.12.005. Epub 2022 Dec 29.ABSTRACTFollicle-stimulating hormone (FSH) and estrogens are fundamental to support reproductive functions. Beside the well-known FSH membrane receptor (FSHR), a G protein-coupled estrogen receptor (GPER) has been found, over the last two decades, in several tissues. It may trigger rapid, non-genomic responses of estradiol, activating proliferative and survival stimuli. The two receptors were co-characterized in the ovary, where they modulate different intracellular signaling cascades, according to the expression level and developmental stage of...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Livio Casarini Manuela Simoni Source Type: research
Structure-function of DHEA binding proteins
Vitam Horm. 2023;123:587-617. doi: 10.1016/bs.vh.2022.12.002. Epub 2022 Dec 16.ABSTRACTDehydroepiandrosterone (3β-hydroxy-5-androsten-17-one, DHEA) and its sulfated metabolite DHEA-S are the most abundant circulating steroids and are precursors for active sex steroid hormones, estradiol and testosterone. DHEA has a broad range of reported effects in the central nervous system (CNS), cardiovascular system, adipose tissue, kidney, liver, and in the reproductive system. The mechanisms by which DHEA and DHEA-S initiate their biological effects are diverse. DHEA and DHEA-S may directly bind to plasma membrane (PM) receptors, i...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Barbara J Clark Carolyn M Klinge Source Type: research
Membrane estrogen receptor and follicle-stimulating hormone receptor
Vitam Horm. 2023;123:555-585. doi: 10.1016/bs.vh.2022.12.005. Epub 2022 Dec 29.ABSTRACTFollicle-stimulating hormone (FSH) and estrogens are fundamental to support reproductive functions. Beside the well-known FSH membrane receptor (FSHR), a G protein-coupled estrogen receptor (GPER) has been found, over the last two decades, in several tissues. It may trigger rapid, non-genomic responses of estradiol, activating proliferative and survival stimuli. The two receptors were co-characterized in the ovary, where they modulate different intracellular signaling cascades, according to the expression level and developmental stage of...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Livio Casarini Manuela Simoni Source Type: research
Structure-function of DHEA binding proteins
Vitam Horm. 2023;123:587-617. doi: 10.1016/bs.vh.2022.12.002. Epub 2022 Dec 16.ABSTRACTDehydroepiandrosterone (3β-hydroxy-5-androsten-17-one, DHEA) and its sulfated metabolite DHEA-S are the most abundant circulating steroids and are precursors for active sex steroid hormones, estradiol and testosterone. DHEA has a broad range of reported effects in the central nervous system (CNS), cardiovascular system, adipose tissue, kidney, liver, and in the reproductive system. The mechanisms by which DHEA and DHEA-S initiate their biological effects are diverse. DHEA and DHEA-S may directly bind to plasma membrane (PM) receptors, i...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Barbara J Clark Carolyn M Klinge Source Type: research
Membrane estrogen receptor and follicle-stimulating hormone receptor
Vitam Horm. 2023;123:555-585. doi: 10.1016/bs.vh.2022.12.005. Epub 2022 Dec 29.ABSTRACTFollicle-stimulating hormone (FSH) and estrogens are fundamental to support reproductive functions. Beside the well-known FSH membrane receptor (FSHR), a G protein-coupled estrogen receptor (GPER) has been found, over the last two decades, in several tissues. It may trigger rapid, non-genomic responses of estradiol, activating proliferative and survival stimuli. The two receptors were co-characterized in the ovary, where they modulate different intracellular signaling cascades, according to the expression level and developmental stage of...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Livio Casarini Manuela Simoni Source Type: research
Pyridoxamine protects human granulosa cells against advanced glycation end-products-induced steroidogenesis disturbances
CONCLUSION: This study indicates that hormonal dysfunctions induced by the AGEs-RAGE axis in luteinized GCs are likely rectified by PM treatment. This effect is likely acquired by reduced expression of RAGE. A better understanding of how AGEs and PM interact in ovarian physiology and pathology may lead to more targeted therapy for treating ovarian dysfunction.PMID:37642758 | DOI:10.1007/s11033-023-08723-8
Source: Molecular Biology Reports - August 29, 2023 Category: Molecular Biology Authors: Maryam Mirani Soghra Bahmanpour Fatemeh Masjedi Zahra Derakhshan Mahintaj Dara Mohammad Hossein Nasr-Esfahani Seyed Mohammad Bagher Tabei Source Type: research
Fertility-enhancing effects of inositol & amp; vitamin C on cisplatin induced ovarian and uterine toxicity in rats via suppressing oxidative stress and apoptosis
This study aimed to explore the effects of Inositol and vitamin C on cisplatin-induced infertility. Forty-eight adult female Wistar rats were divided into eight groups (N = 6) and orally treated for 21 days. The treatments were as follows: negative control (saline), positive control (saline and cisplatin injected into the abdomen on day 15), T1-T3: rats given vitamin C (150 mg/kg), Inositol (420 mg/kg), and vitamin C + Inositol, respectively, along with cisplatin injected into the abdomen on day 15, T4-T6: rats given only vitamin C, Inositol, and vitamin C + Inositol, respectively. Vitamin C and Inositol enhanced cisplatin...
Source: Food and Chemical Toxicology - August 24, 2023 Category: Food Science Authors: Amir Hosein Moslehi Fatemeh Hoseinpour Amir Saber Maryam Akhavan Taheri Amir Hossein Hashemian Source Type: research
Determination of lipemia acceptance thresholds for 31 immunoassay analytes
CONCLUSION: Most immunoassays evaluated in this study were found to be robust to lipemia interference. By using these thresholds, laboratories can report the immunoassay results from analyzing a lipemic patient sample in many cases.PMID:37572842 | DOI:10.1016/j.cca.2023.117508
Source: International Journal of Clinical Chemistry - August 12, 2023 Category: Chemistry Authors: Şerif Ercan Mustafa Tat Source Type: research
