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Drug: Metformin
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Total 6422 results found since Jan 2013.
Short period-administration of myo-inositol and metformin on hormonal and glycolipid profiles in patients with polycystic ovary syndrome: a systematic review and updated meta-analysis of randomized controlled trials
CONCLUSIONS: Compared with metformin, the suitable supplemental dosage of myo-ins may be helpful in lowering levels of TG and avoiding adverse events (AEs).PMID:35363325 | DOI:10.26355/eurrev_202203_28322
Source: Pharmacological Reviews - April 1, 2022 Category: Drugs & Pharmacology Authors: J-Q Zhang C Xing B He Source Type: research
Arguing for More, and More Rigorous, Drug Repurposing Efforts to Slow Aging
The authors of today's open access paper argue for much greater effort to be directed towards the repurposing of existing drugs with the goal of slowing aging. I have mixed feelings about the prevalence of drug repurposing in the pharmaceutical industry. The FDA makes it so very expensive to introduce any new drug that industry of course responds to the incentives and spends a great deal of time digging through the existing library of approved drugs in search of those that can be used in different circumstances. It is a great deal easier to take a drug with established safety data and seek approval for a new use than it is...
Source: Fight Aging! - April 7, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, April 11th 2022
In conclusion, plasma levels of IGHA2, APOA and HPT are associated with subclinical atherosclerosis independently of traditional risk factors and offers potential to predict this disease. The panel could improve primary prevention strategies in areas where imaging is not available.
A Lesser Diversity of Circulating Antibodies in the Aging Killifish Immune System
https://www.fightaging.org/archives/2022/04/a-lesser-diversity-of-circulating-antibodies-in-the-aging-killifish-immune-system/
Short-lived killifish are one of the more recently adopted animal models of aging. All such models are a trade-off betw...
Source: Fight Aging! - April 10, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Obesity and breast cancer risk: the oncogenic implications of metabolic dysregulation
CONCLUSION: Incorporating markers of metabolic health and body composition measures with body mass index can capture breast cancer risk more comprehensively. Further studies of interventions targeting body fat levels are needed to curb the growing prevalence of obesity-related cancer.PMID:35453151 | DOI:10.1210/clinem/dgac241
Source: Clinical Breast Cancer - April 22, 2022 Category: Cancer & Oncology Authors: Sandra Naaman Sherry Shen Meltem Zeytinoglu Neil M Iyengar Source Type: research
The role of metformin in the treatment of dermatological diseases: A narrative review
CONCLUSIONS: Metformin is an effective and safe adjuvant in the therapeutic scheme of various inflammatory dermatoses, skin neoplasms, endocrinology-related dermatosis, melasma, skin aging and wound healing processes.PMID:35569426 | DOI:10.1016/j.aprim.2022.102354
Source: Atencion Primaria - May 15, 2022 Category: Primary Care Authors: Juan Monte-Serrano Pablo Villagrasa-Boli Joana Crua ñes-Monferrer Patricia Arbu és-Espinosa Sara Mart ínez-Cisneros Miguel Fernando Garc ía-Gil Source Type: research
Antidiabetic Drugs and their Potential Use in COVID-19: A Mechanistic Approach
Endocr Metab Immune Disord Drug Targets. 2022 May 16. doi: 10.2174/1871530322666220516115604. Online ahead of print.ABSTRACTMany therapies have been developed against COVID-19 since it first appeared in December 2019. Antivirals, antimalarials, cephalosporins, colchicine, anticoagulants, corticosteroids, among others, have been evaluated as protecting agents against antibacterial complications due to their anti-inflammatory and immunomodulatory effects against thrombosis and cell death caused by infection with SARS-CoV-2. Nevertheless, the overall balance in their application has not been found to be satisfactory. On the o...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - May 17, 2022 Category: Endocrinology Authors: Bryan Alejandro Espinosa-Rodriguez Aissa Michelle Nieto-Moreno Jose Luis Gonzalez Llerena Tania Alejandra Rico-Torres Pilar Carranza-Rosales Luis Fernando Mendez-Lopez Isaias Balderas-Renteria Source Type: research
Effects of Drugs and Chemotherapeutic Agents on Dental Implant Osseointegration: Narrative Review
CONCLUSION: Systemic medications that enhance osseointegration include mineralization promoters and bone resorption inhibitors. On the other hand, medications often given to the elderly with systemic problems might interfere with osseointegration, leading to implant failure. However, to validate the provided research, more human studies with a higher level of evidence are required.PMID:35674294 | DOI:10.2174/2772432817666220607114559
Source: Pharmacological Reviews - June 8, 2022 Category: Drugs & Pharmacology Authors: Aida Mohammadi Nazanin Roqani Dehkordi Sadaf Mahmoudi Niyousha Rafeie Hamoun Sabri Maryam Valizadeh Taniya Poorsoleiman Aryan Jafari Alireza Mokhtari Arshia Khanjarani Yasaman Salimi Melika Mokhtari Niloofar Deravi Source Type: research
