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Epilepsia Partialis Continua Secondary To Ischemic Stroke, Responsive To The Combination Of Levetiracetam And Lacosamide (P4.255)
CONCLUSIONS: EPC represents a condition commonly refractory to AED. We report two cases of EPC secondary to subacute and chronic IS that showed responsiveness to the combination of levetiracetam and lacosamide. Further evaluation of this AED combination in treating this difficult condition is needed.Disclosure: Dr. Thompson has nothing to disclose. Dr. Murr has nothing to disclose. Dr. Fayad has received research support from the National Institute of Neurological Disorders and Stroke, and St Jude Medical.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Thompson, R., Murr, N., Fayad, P. Tags: Epilepsy and Clinical Neurophysiology (EEG): Status Epilepticus Source Type: research

Dysarthria-Facial Paresis and Rostral Pontine Ischemic Stroke
We describe an acute, postoperative dysarthria-facial paresis. While the rare stroke syndrome has been described previously, we present an under-described clinical nuance to its presentation with a particularly clear imaging correlation. A 78-year-old, right-handed man with a past medical history of aortic stenosis presented after a transcatheter aortic valve replacement. Immediately postoperatively, no neurological deficits were noted. That evening, he described his speech as “drunken.” He was later noted to have a right lower facial droop in addition to the speech change. His speech exhibited labial, lingual, and (to...
Source: Case Reports in Neurology - March 10, 2022 Category: Neurology Source Type: research

Combination of Dexmedetomidine and Ketamine for Magnetic Resonance Imaging Sedation
Conclusions: The efficacy of DEX–KET sedation was comparable to that of midazolam for MRI examination. DEX–KET was related to shorter scan time and lower occurrence of complications compared to midazolam. Introduction Neurocritically ill patients often require brain magnetic resonance imaging (MRI) in addition to conventional neurological evaluations. Brain MRI can reveal structural lesions with a high sensitivity due to its excellent spatial resolution and enhanced soft tissue contrast (1–3). To acquire MRI images, patients' cooperation is imperative. However, keeping patients with ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

De novo status epilepticus with isolated aphasia.
CONCLUSIONS: Magnetic resonance imaging findings were only subtle, and EEG was without clear ictal pattern, so the diagnosis of aphasic status remains with some uncertainty. However, status epilepticus can mimic stroke symptoms and has to be considered in patients with aphasia even when no previous stroke or structural lesions are detectable and EEG shows no epileptic discharges. Epileptic origin is favored when CT or MR imaging reveal no hypoperfusion. In this case, MRI was superior to CT in detecting hyperperfusion. This article is part of a Special Issue entitled "Status Epilepticus". PMID: 26044094 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - June 1, 2015 Category: Neurology Authors: Flügel D, Kim OC, Felbecker A, Tettenborn B Tags: Epilepsy Behav Source Type: research

De novo status epilepticus with isolated aphasia
Conclusions Magnetic resonance imaging findings were only subtle, and EEG was without clear ictal pattern, so the diagnosis of aphasic status remains with some uncertainty. However, status epilepticus can mimic stroke symptoms and has to be considered in patients with aphasia even when no previous stroke or structural lesions are detectable and EEG shows no epileptic discharges. Epileptic origin is favored when CT or MR imaging reveal no hypoperfusion. In this case, MRI was superior to CT in detecting hyperperfusion. This article is part of a Special Issue entitled “Status Epilepticus”.
Source: Epilepsy and Behavior - June 12, 2015 Category: Neurology Source Type: research

Simple Partial Status Epilepticus One-Day Post Single-Pulse TMS to the Affected Hemisphere in a Participant with Chronic Stroke
We report a TMS-related seizure. A 51-year-old man 8 months post superior sagittal vein thrombosis reported “twitching” in his affected arm, leg, and face one day after participating in a TMS trial. The day prior to the seizure event, the patient received 70 trials of single pulse TMS over the unaffected hemisphere primary motor cortex and double-pulse stimulation applied first over dorsal premotor cortex of the affected hemisphere (80 trials) and then over primary motor cortex of the affected hemisphere (70 trials). The twitching persisted nearly continuously for two days despite administration of lorazepam and low do...
Source: Brain Stimulation - March 13, 2015 Category: Neurology Source Type: research

Nursing Home Residents with Seizure Disorders/Epilepsy: Prevalence, Characteristics, and Treatment Patterns (P1.080)
Conclusions: NHRs with seizure disorder/epilepsy have substantial physical and cognitive impairment. Nearly half were prescribed combination AED therapy, and >20[percnt] took 蠅3 different AEDs, suggesting refractory epilepsy. Additional research is needed to assess treatment outcomes and further define optimal care in this population.Disclosure: Dr. Zarowitz has nothing to disclose. Dr. Allen has nothing to disclose. Dr. OShea has nothing to disclose. Dr. Wang has nothing to disclose. Dr. Semenchuk has nothing to disclose. Dr. Barghout has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zarowitz, B., Allen, C., OShea, T., Wang, Z., Semenchuk, M., Barghout, V. Tags: Epilepsy/Clinical Neurophysiology: Geriatric Epilepsy, Epidemiology, and Health Services Source Type: research

Sporadic Creutzfeldt-Jakob Disease Presenting as Non-Convulsive Status Epilepticus: A Case Report (P1.333)
CONCLUSIONS: Non-convulsive status epilepticus is an extremely rare presentation of prion disease. To date, there have only been three reported cases in the literature. This case highlights the need to consider prion disease as an etiology in NCSE and NORSE.Disclosure: Dr. Alobaidy has nothing to disclose. Dr. Parker has nothing to disclose. Dr. Bershad has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Alobaidy, A., Parker, A., Bershad, E. Tags: Fungal and Other Infectious Disorders Source Type: research

A case of non-febrile seizures due to chronic salicylate intoxication following prolonged household exposure to incense stick fumes (p3.250)
Conclusion: All salicylate-containing products should have an appropriate warning label. It is important that health care providers are aware of the potential risk.Disclosure: Dr. Shekhawat has nothing to disclose. Dr. Rajagopalan has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Shekhawat, P., Rajagopalan, L. Tags: Child Neurology and Developmental Neurology: Epilepsy, Hypoxia, and Stroke Source Type: research

Severe Hypoxia with Status Epilepticus as a Possible Etiology of Sudden Death in Lesch Nyhan Syndrome: A Case Report and Review of the Literature (P3.252)
CONCLUSIONS: Severe hypoxia secondary to unrecognized nocturnal seizures may be an etiology of sudden death in Lesch Nyhan syndrome. Neurotransmitter abnormalities have been described in LNS, including alterations in adenosine, a neurotransmitter associated with death from seizure in animal models. This could be responsible for increased incidence of sudden death from seizures in LNS.Disclosure: Dr. Christy has nothing to disclose. Dr. Wilson has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Christy, A., Wilson, J. Tags: Child Neurology and Developmental Neurology: Epilepsy, Hypoxia, and Stroke Source Type: research