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Drug: Fortamet
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Total 6511 results found since Jan 2013.
Rationality, Efficacy, Tolerability of Empagliflozin plus Linagliptin Combination for the Management of Type 2 Diabetes Mellitus: A Systematic review of randomized controlled trials and observational studies
CONCLUSION: After reviewing findings from the available clinical studies of the combination of empagliflozin plus linagliptin we conclude that, the combination is effective, safe, tolerable and rationale cost effective combination compared to placebo and either drug alone for the management of T2DM in patients with inadequate glycemic control with metformin alone, patients with intoleratance to metformin, increased baseline HbA1c, patients with overweight or obesity and diabetic hypertensive, CHF, atherosclerotic cardiovascular disease and renal dysfunction patients. We suggest for more number of future randomized controll...
Source: Current Diabetes Reviews - September 13, 2021 Category: Endocrinology Authors: Santenna Chenchul Shoban Babu Varthya Padmavathi R Source Type: research
Does metformin improve reproduction outcomes for non-obese, infertile women with polycystic ovary syndrome? Meta-analysis and systematic review
CONCLUSION: Although this study illustrated that metformin may be better than placebo for some pregnancy outcomes, stronger, more definitive evidence from sufficiently powered trials are required before considering metformin for treating non-obese infertile women with PCOS within the current recommended guidelines.PMID:35149444 | DOI:10.1016/j.ejogrb.2022.01.025
Source: Reproductive Biology - February 12, 2022 Category: Reproduction Medicine Authors: Reem Magzoub Elrasheid A H Kheirelseid Claire Perks Sarah Lewis Source Type: research
Pharmacological Interventions of Atypical Antipsychotics Induced Weight Gain in the Pediatric Population: A Systemic Review of Current Evidence
Child Psychiatry Hum Dev. 2022 Sep 6. doi: 10.1007/s10578-022-01424-6. Online ahead of print.ABSTRACTTo systematically review studies evaluating pharmacological treatment intervention of the atypical antipsychotic induced weight gain in the pediatric population and summarize the current evidence of the pharmacological treatment. According to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines, we searched the various databases Medline, PubMed, PubMed central (PMC), CINAHL, and clinicaltrial.gov. until Jan 30th, 2022 for relevant clinical studies. Medical subject heading (MeSH) terms o...
Source: Child Psychiatry and Human Development - September 6, 2022 Category: Child Development Authors: Wisam Al Jumaili Ashraf Muzwagi Kaushal Shah Chintan Trivedi Priya Durga Zeeshan Mansuri Shailesh Jain Yousif Al Jumaili Source Type: research
Is metformin neuroprotective against diabetes mellitus-induced neurodegeneration? An updated graphical review of molecular basis
Pharmacol Rep. 2023 Apr 24. doi: 10.1007/s43440-023-00469-1. Online ahead of print.ABSTRACTDiabetes mellitus (DM) is a metabolic disease that activates several molecular pathways involved in neurodegenerative disorders. Metformin, an anti-hyperglycemic drug used for treating DM, has the potential to exert a significant neuroprotective role against the detrimental effects of DM. This review discusses recent clinical and laboratory studies investigating the neuroprotective properties of metformin against DM-induced neurodegeneration and the roles of various molecular pathways, including mitochondrial dysfunction, oxidative s...
Source: Pharmacological Reports - April 24, 2023 Category: Drugs & Pharmacology Authors: Fatemeh Karami Hamidreza Jamaati Natalie Coleman-Fuller Maryam Shokrian Zeini A Wallace Hayes Mina Gholami Mahsa Salehirad Mohammad Darabi Majid Motaghinejad Source Type: research
Efficacy and Safety of Triple Therapy with SGLT-2 Inhibitor, DPP-4 Inhibitor, and Metformin in Type 2 Diabetes: A Meta-Analysis
CONCLUSIONS: Based on current evidence, triple therapy was found to significantly improve blood glucose, body weight, and blood pressure when compared to dual therapy. Safety indicators did not show significant differences, except for an increased risk of genital tract infection.PMID:37171944
Source: Alternative Therapies in Health and Medicine - May 12, 2023 Category: Complementary Medicine Authors: Mengdi Li Sining Wang Xiaoli Wang Source Type: research
