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Prolonged Maternal Separation Induces the Depression-Like Behavior Susceptibility to Chronic Unpredictable Mild Stress Exposure in Mice
Biomed Res Int. 2021 Jul 29;2021:6681397. doi: 10.1155/2021/6681397. eCollection 2021.ABSTRACTEarly life stress is an important determinant for developing depression later in life. It is reported that maternal separation (MS) could trigger stress sensitivity in adulthood when exposed to stress again. However, it could also result in resilience to stress-induced depression. The conclusions are contradictory. To address this issue, C57BL/6N newborn pups were exposed to either daily short MS (MS for 15 min per day; MS15) or prolonged MS (MS for 180 min per day; MS180) from the first day postpartum (PD1) to PD21. Adult mice we...
Source: Biomed Res - August 9, 2021 Category: Research Authors: Yaoyao Bian Yanting Ma Qian Ma Lili Yang Qinmei Zhu Wenlin Li Lingdong Meng Source Type: research

Characterization of Endophytic Fungi, < em > Acremonium < /em > sp., from < em > Lilium davidii < /em > and Analysis of Its Antifungal and Plant Growth-Promoting Effects
In this study, the fungal endophyte Acremonium sp. Ld-03 was isolated from the bulbs of L. davidii and identified through morphological and molecular analysis. The molecular and morphological analysis confirmed the endophytic fungal strain as Acremonium sp. Ld-03. Antifungal effects of Ld-03 were observed against Fusarium oxysporum, Botrytis cinerea, Botryosphaeria dothidea, and Fusarium fujikuroi. The highest growth inhibition, i.e., 78.39 ± 4.21%, was observed for B. dothidea followed by 56.68 ± 4.38%, 43.62 ± 3.81%, and 20.12 ± 2.45% for B. cinerea, F. fujikuroi, and F. oxysporum, respectively. Analysis of the ethyl...
Source: Biomed Res - August 16, 2021 Category: Research Authors: Mohammad Sayyar Khan Junlian Gao Iqbal Munir Mingfang Zhang Yixin Liu The Su Moe Jing Xue Xiuhai Zhang Source Type: research

Husband Support Mediates the Association between Self-Efficacy and Cervical Cancer Screening among Women in the Rural Area of Indonesia
CONCLUSIONS: Our analysis revealed a route through which husband help influences the use of VIA tests among women in Indonesian rural areas. Providers must consider the effect of husband support on VIA testing in promoting the use of VIA tests among females in Indonesia. One potential communication approach is that providers make improvements to improve the use of VIA tests in supporting self-efficacy.PMID:34527786 | PMC:PMC8420921 | DOI:10.4103/apjon.apjon-2085
Source: Rural Remote Health - September 16, 2021 Category: Rural Health Authors: None Juwitasari Ririn Harini Achmad Ainur Rosyad Source Type: research

Odontogenic gene expression profile of human dental pulp-derived cells under high glucose influence: a microarray analysis
CONCLUSIONS: The high-glucose condition significantly inhibited the mineralization of hDPCs. DEGs were identified, and interestingly, HAS1 and Fbln-7 genes may be involved in the glucose inhibitory effect on hDPC mineralization.PMID:34586189 | PMC:PMC8477757 | DOI:10.1590/1678-7757-2020-1074
Source: Appl Human Sci - September 29, 2021 Category: Physiology Authors: Sivaporn Horsophonphong Hathaitip Sritanaudomchai Siriruk Nakornchai Nakarin Kitkumthorn Rudee Surarit Source Type: research

The Effect of Salt-Tolerant Antagonistic Bacteria CZ-6 on the Rhizosphere Microbial Community of Winter Jujube ( < em > Ziziphus jujuba < /em > Mill. "Dongzao") in Saline-Alkali Land
Biomed Res Int. 2021 Sep 24;2021:5171086. doi: 10.1155/2021/5171086. eCollection 2021.ABSTRACTAs the main economic crop cultivated in the Yellow River Delta, winter jujube contains various nutrients. However, soil salinization and fungal diseases have affected the yield and quality of winter jujube. In order to use plant growth-promoting rhizobacteria (PGPR) to reduce these damages, the antagonistic bacteria CZ-6 isolated from the rhizosphere of wheat in saline soil was selected for experiment. Gene sequencing analysis identified CZ-6 as Bacillus amyloliquefaciens. In order to understand the salt tolerant and disease-resis...
Source: Biomed Res - October 6, 2021 Category: Research Authors: YanYan Zhou LiPing Hao Chao Ji QiSheng Zhou Xin Song Yue Liu HuYing Li ChaoHui Li QiXiong Gao JinTai Li PengCheng Zhang XunLi Liu Source Type: research

< em > Stauntonia hexaphylla < /em > leaf extract (YRA-1909) suppresses inflammation by modulating Akt/NF- κB signaling in lipopolysaccharide-activated peritoneal macrophages and rodent models of inflammation
CONCLUSIONS: S. hexaphylla leaf extract YRA-1909 had anti-inflammatory activity in vitro and in vivo that involves modulation of Akt/NF-κB signaling. Thus, YRA-1909 is safe and effective for the treatment of inflammation.PMID:34776829 | PMC:PMC8559446 | DOI:10.29219/fnr.v65.7666
Source: Food and Nutrition Research - November 15, 2021 Category: Nutrition Authors: Jaeyong Kim Gyuok Lee Huwon Kang Ji-Seok Yoo Yongnam Lee Hak-Sung Lee Chul-Yung Choi Source Type: research

Analgesic and Anti-Inflammatory Activities of Sophocarpine from < em > Sophora viciifolia < /em > Hance
Biomed Res Int. 2021 Nov 8;2021:8893563. doi: 10.1155/2021/8893563. eCollection 2021.ABSTRACTSophora viciifolia Hance is an edible plant used in traditional Chinese medicine. Sophocarpine, a tetracyclic quinolizidine alkaloid, is one of the most abundant active ingredients in Sophora viciifolia Hance. Here, we study the analgesic and anti-inflammatory effects, as well as the acute toxicity of sophocarpine from Sophora viciifolia Hance in mice. Sophocarpine (20, 40, and 80 mg/kgbw) significantly prolonged the delay period before a hot plate reaction occurred (all P < 0.05), and the delay before a tail-flick response was ...
Source: Biomed Res - November 18, 2021 Category: Research Authors: F L Wang H Wang J H Wang D X Wang Y Gao B Yang H J Yang Y B Ji G S Xin Source Type: research

< em > Stauntonia hexaphylla < /em > leaf extract (YRA-1909) suppresses inflammation by modulating Akt/NF- κB signaling in lipopolysaccharide-activated peritoneal macrophages and rodent models of inflammation
CONCLUSIONS: S. hexaphylla leaf extract YRA-1909 had anti-inflammatory activity in vitro and in vivo that involves modulation of Akt/NF-κB signaling. Thus, YRA-1909 is safe and effective for the treatment of inflammation.PMID:34776829 | PMC:PMC8559446 | DOI:10.29219/fnr.v65.7666
Source: Food and Nutrition Research - November 15, 2021 Category: Nutrition Authors: Jaeyong Kim Gyuok Lee Huwon Kang Ji-Seok Yoo Yongnam Lee Hak-Sung Lee Chul-Yung Choi Source Type: research