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Navigating Practice Issues Related to the Unsatisfactory Cervicovaginal Papanicolaou Test: Survey Results of Laboratories Participating in the 2020 College of American Pathologists PAP Education Program
CONCLUSIONS.—: This CAP survey reveals important information regarding the practice patterns pertaining to several aspects of the unsatisfactory Pap test. It also provides valuable insight into the quality assurance measures that can be implemented for such tests. Future studies can further aid in the standardization of all components of the handling of unsatisfactory Pap tests for overall quality improvement.PMID:37074866 | DOI:10.5858/arpa.2022-0330-CP
Source: Archives of Pathology and Laboratory Medicine - April 20, 2023 Category: Laboratory Medicine Authors: Abha Goyal Christine N Booth Rhona J Souers Sana O Tabbara Janie Roberson Michael R Henry Kaitlin E Sundling Kelly Goodrich Lananh Nguyen Source Type: research

Cervical cancer prevention in countries with the highest HIV prevalence: a review of policies
CONCLUSION: Considerable progress has been made in policy development for CC prevention and control in sub Saharan Africa. However, in countries with a high HIV burden, there is need to tailor these policies to respond to the specific needs of WLHIV. Countries may consider updating policies using the recent WHO guidelines for CC prevention, while adapting them to context realities.PMID:35948944 | DOI:10.1186/s12889-022-13827-0
Source: Cancer Control - August 10, 2022 Category: Cancer & Oncology Authors: Serra Lem Asangbeh-Kerman Ma ša Davidović Katayoun Taghavi James Kachingwe Kereng Molly Rammipi Laura Muzingwani Magaret Pascoe Marielle Jousse Masangu Mulongo Mulindi Mwanahamuntu Neo Tapela Oluwasanmi Akintade Partha Basu Xolisile Dlamini Julia Bohliu Source Type: research

Screening technologies for cervical cancer: Overview
Cytojournal. 2022 Mar 29;19:23. doi: 10.25259/CMAS_03_04_2021. eCollection 2022.ABSTRACTEver since the introduction of the Papanicolaou (PAP) smear test was published in 1941 in American Journal of Obstetrics and Gynecology, PAP test linked with definitive treatment has prevented millions of women from cervical cancer in the developed countries. Due to limited availability of resources, a lack of infrastructure and difficulty in getting highly trained professionals, widespread implementation of PAP test dependent cervical cancer screening program has not been established in low and middle income countries such as India. Th...
Source: Cancer Control - May 5, 2022 Category: Cancer & Oncology Authors: Dipanwita Banerjee Srabani Mittal Ranajit Mandal Partha Basu Source Type: research

Husband Support Mediates the Association between Self-Efficacy and Cervical Cancer Screening among Women in the Rural Area of Indonesia
CONCLUSIONS: Our analysis revealed a route through which husband help influences the use of VIA tests among women in Indonesian rural areas. Providers must consider the effect of husband support on VIA testing in promoting the use of VIA tests among females in Indonesia. One potential communication approach is that providers make improvements to improve the use of VIA tests in supporting self-efficacy.PMID:34527786 | PMC:PMC8420921 | DOI:10.4103/apjon.apjon-2085
Source: Rural Remote Health - September 16, 2021 Category: Rural Health Authors: None Juwitasari Ririn Harini Achmad Ainur Rosyad Source Type: research

Detailed Dissection of UBE3A-Mediated DDI1 Ubiquitination
Discussion Poly-ubiquitinated proteins targeted for degradation might be recognized directly by proteasomal receptors or by proteasomal shuttling proteins. The first shuttling proteins – Ddi1, Rad23 and Dsk2 – were identified and characterized in Saccharomyces cerevisiae (Lambertson et al., 1999; Kaplun et al., 2005). Proteasomal shuttles contain an N-terminal ubiquitin-like (UBL) domain that interacts with the 26S proteasome (Finley, 2009), and a C-terminal ubiquitin-binding domain domain (UBD) that binds to ubiquitin or poly-ubiquitin chains (Bertolaet et al., 2001). When ubiquitinated, substrates are capt...
Source: Frontiers in Physiology - May 2, 2019 Category: Physiology Source Type: research

Systematic reviews and meta-analyses of the accuracy of HPV tests, visual inspection with acetic acid, cytology, and colposcopy
Conclusions Although differences in sensitivity between tests could be interpreted as large, absolute differences in missed diagnoses were small. By contrast, small differences in specificity resulted in fairly large absolute differences in overtreatment.
Source: International Journal of Gynecology and Obstetrics - November 12, 2015 Category: OBGYN Source Type: research