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Total 638 results found since Jan 2013.

Anti-stroke drug taken by millions found to be 'unreliable' and fatal side effects were ignored
In 2009, distinguished British medical journal The Lancet published a major study on the blood thinner rivaroxaban, which appeared to show it was safe and effective.
Source: the Mail online | Health - January 8, 2023 Category: Consumer Health News Source Type: news

Empagliflozin cardiovascular and renal effectiveness and safety compared to dipeptidyl peptidase-4 inhibitors across 11 countries in Europe and Asia: Results from the EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) study
Diabetes Metab. 2023 Jan 3:101418. doi: 10.1016/j.diabet.2022.101418. Online ahead of print.ABSTRACTBACKGROUND: Continued expansion of indications for sodium-glucose cotransporter-2 inhibitors increases importance of evaluating cardiovascular and kidney efficacy and safety of empagliflozin in patients with type 2 diabetes compared to similar therapies.METHODS: The EMPRISE Europe and Asia study is a non-interventional cohort study using data from 2014-2019 in seven European (Denmark, Finland, Germany, Norway, Spain, Sweden, United Kingdom) and four Asian (Israel, Japan, South Korea, Taiwan) countries. Patients with type 2 d...
Source: Diabetes and Metabolism - January 7, 2023 Category: Endocrinology Authors: Avraham Karasik Stefanie Lanzinger Elise Chia-Hui Tan Daisuke Yabe Dae Jung Kim Wayne H-H Sheu Cheli Melzer-Cohen Reinhard W Holl Kyoung Hwa Ha Kamlesh Khunti Francesco Zaccardi Anuradhaa Subramanian Krishnarajah Nirantharakumar Thomas Nystr öm Leo Niska Source Type: research

The incidence and prevalence of epilepsy in the United Kingdom 2013 –2018: A retrospective cohort study of UK primary care data
The estimated incidence (50 –80 per 100,000 person-years) and prevalence rates (5–10 per 1000 person / year) for epilepsy have been found to be relatively consistent across high income countries [1–3]. Nevertheless, changes in demographics and risk factors mean that the epidemiology of epilepsy may change over time. For instance, in countries with an aging population, the increasing prevalence of diseases of old age such as stroke or dementia could increase the prevalence of epilepsy. Conversely, improved General Practitioner (GP) and specialist training, improved guidance for clinicians, better obstetric care and mo...
Source: Seizure: European Journal of Epilepsy - January 5, 2023 Category: Neurology Authors: S Wigglesworth, A Neligan, JM Dickson, A Pullen, E Yelland, T Anjuman, M Reuber Source Type: research

The Incidence and Prevalence of Epilepsy in the United Kingdom 2013-2018: a retrospective cohort study of UK primary care data.
The estimated incidence (50-80 per 100,000 person-years) and prevalence rates (5-10 per 1000 person / year) for epilepsy have been found to be relatively consistent across high income countries [1 –3]. Nevertheless, changes in demographics and risk factors mean that the epidemiology of epilepsy may change over time. For instance, in countries with an aging population, the increasing prevalence of diseases of old age such as stroke or dementia could increase the prevalence of epilepsy. Conve rsely, improved General Practitioner (GP) and specialist training, improved guidance for clinicians, better obstetric care and more ...
Source: Seizure: European Journal of Epilepsy - January 5, 2023 Category: Neurology Authors: S Wigglesworth, A Neligan, JM Dickson, A Pullen, E Yelland, T Anjuman, M Reuber Source Type: research

The final puff: Can New Zealand quit smoking for good?
Smoking kills. Ayesha Verrall has seen it up close. As a young resident physician in New Zealand’s public hospitals in the 2000s, Verrall watched smokers come into the emergency ward every night, struggling to breathe with their damaged lungs. Later, as an infectious disease specialist, she saw how smoking exacerbated illness in individuals diagnosed with tuberculosis and HIV/AIDS. She would tell them: “The best thing you can do to promote your health, other than take the pills, is to quit smoking.” Verrall is still urging citizens to give up cigarettes—no longer just one by one, but by the thousands. As New...
Source: ScienceNOW - December 9, 2022 Category: Science Source Type: news

Cost-effectiveness of carotid endarterectomy in symptomatic patients
CONCLUSION: Surgery may not now be clinically effective and cost-effective in those with moderate carotid stenosis. However, these results are uncertain because of the limited data on modern medical therapy and an RCT may be justified.PMID:36422995 | DOI:10.1093/bjs/znac386
Source: The British Journal of Surgery - November 24, 2022 Category: Surgery Authors: Daniel Perez-Troncoso David Epstein Alun Huw Davies Ankur Thapar Source Type: research

A different way of life: a qualitative study on the experiences of family caregivers of stroke survivors living at home
Br J Community Nurs. 2022 Nov 2;27(11):558-566. doi: 10.12968/bjcn.2022.27.11.558.ABSTRACTThere are approximately 1.3 million stroke survivors in the UK, with the majority of them relying on family caregivers for support. However, the needs of family caregivers are not routinely assessed by most services. The aim of this study was to explore the experiences of stroke family caregivers following the implementation of the Care Act, 2014. A total of 16 semi-structured, digitally recorded face-to-face qualitative interviews were conducted with a purposive sample of stroke family caregivers in north-west England. Thematic analy...
Source: British Journal of Community Nursing - November 3, 2022 Category: Nursing Authors: Emmie Malewezi Mary R O'Brien Katherine Knighting Juliet Thomas Barbara Jack Source Type: research