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Procedure: Kidney Transplant
Countries: Netherlands Health
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Total 639 results found since Jan 2013.
Urinary copper excretion is associated with long-term graft failure in kidney transplant recipients
Conclusion In KTR, urinary protein excretion is positively correlated with urinary copper excretion. In turn, higher urinary copper excretion is associated with an independent increased risk of kidney graft failure, with a substantial mediating effect through oxidative tubular damage. Further studies are warranted to investigate whether copper excretion-targeted interventions could improve kidney graft survival.PMID:37231776 | DOI:10.1159/000531147
Source: American Journal of Nephrology - May 26, 2023 Category: Urology & Nephrology Authors: Manuela Yepes-Calderon Daan Kremer Adrian Post Camilo G Sotomayor Ulrike Seidel Patricia Huebbe Tim J Knobbe Kai L üersen Michele Freerk Eisenga Eva Corpeleijn Martin H de Borst Gerjan Navis Gerald Rimbach Stephan J L Bakker Source Type: research
Mycophenolic acid exposure determines antibody formation following SARS-CoV-2 vaccination in kidney transplant recipients: a nested cohort study
This study demonstrates the exposure-response relationship between gold standard MPA exposure and antibody formation to support interventional studies investigating MPA adjustment to improve antibody formation after further boostering.PMID:36789469 | DOI:10.1002/cpt.2872
Source: Clinical Pharmacology and Therapeutics - February 15, 2023 Category: Drugs & Pharmacology Authors: Soufian Meziyerh Pim Bouwmans Teun van Gelder Danny van der Helm Lianne Messchendorp Paul J M van der Boog Johan W de Fijter Dirk Jan A R Moes Aiko P J de Vries RECOVAC Collaborators Source Type: research
Sustained employment, work disability and work functioning in CKD patients: a cross-sectional survey study
CONCLUSIONS: Employed CKD patients experience difficulties regarding functioning in work requiring adjustment of work or partial work disability. In addition to dialysis patients, stage G3b-G5 patients are vulnerable concerning sustained employment and work functioning.PMID:36315355 | DOI:10.1007/s40620-022-01476-w
Source: Journal of Nephrology - October 31, 2022 Category: Urology & Nephrology Authors: Manna A Alma Sijrike F van der Mei Sandra Brouwer Luuk B Hilbrands Paul J M van der Boog Herma Uiterwijk Femke Waanders Maaike Hengst Ron T Gansevoort Annemieke Visser Source Type: research
Single antigen testing to reduce early antibody-mediated rejection risk in female recipients of a spousal donor kidney
Transpl Immunol. 2021 May 8:101407. doi: 10.1016/j.trim.2021.101407. Online ahead of print.ABSTRACTFemale recipients of a spousal donor kidney transplant are at greater risk of donor-specific pre-immunization, which may increase the risk of acute antibody-mediated rejection (ABMR). We assessed the incidence of early ABMR (within two weeks after transplantation), risk factors for ABMR and graft function in 352 complement-dependent cytotoxicity test-negative LURD transplant recipients, transplanted between 1997 and 2014 at the Leiden University Medical Center in The Netherlands. Risk factors for immunization were retrieved f...
Source: Transplant Immunology - May 11, 2021 Category: Transplant Surgery Authors: Koen E Groeneweg Fr éderique A van der Toorn Dave L Roelen Cees van Kooten Sebastiaan Heidt Frans H J Claas Marlies E J Reinders Johan W de Fijter Darius Soonawala Source Type: research
Fight Aging! Newsletter, February 8th 2021
This study was divided in two phases: CALERIE-1 and CALERIE-2. CALERIE-1 study was performed to assess the possible effects induced by a reduction of 10-30% of caloric intake on body composition parameters and lipid profile after 6 and 12 months in a population of middle-aged non-obese subjects. CALERIE-1 results showed an improvement in lipid and glycemic profile and a reduction in body weight (BW) and fat mass.
CALERIE-2 was the largest multi-center study on CRD. A total of 220 subjects were enrolled randomly with a 2:1 allocation into two subgroups: 145 in the CRD group and 75 in the ad libitum group. The CRD gro...
Source: Fight Aging! - February 7, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, January 18th 2021
In this study, Desferal, deferoxamine mesylate for injection, which is approved for the treatment of acute iron intoxication and chronic iron overload, was used to explore the beneficial effects on preventing aging-induced bone loss and mitigating dysfunction of aged BMSCs. High-dose Desferal significantly prevented bone loss in aged rats. Compared with controls, the ex vivo experiments showed that short-term Desferal administration could promote the potential of BMSC growth and improve the rebalance of osteogenic and adipogenic differentiation, as well as rejuvenate senescent BMSCs and revise the expression of stemness/se...
Source: Fight Aging! - January 17, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
