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Is Cognitive Reserve Associated with the Prevention of Cognitive Decline After Stroke? A Systematic Review and Meta-Analysis
Ageing Res Rev. 2022 Dec 3:101814. doi: 10.1016/j.arr.2022.101814. Online ahead of print.NO ABSTRACTPMID:36473672 | DOI:10.1016/j.arr.2022.101814
Source: Ageing Research Reviews - December 6, 2022 Category: Genetics & Stem Cells Authors: Israel Contador Patricia Alzola Yaakov Stern Alejandro de la Torre-Luque F élix Bermejo-Pareja Bernardino Fern ández-Calvo Source Type: research

GSE203399 Study of the DNA methylation in the stroke outcome: an Epigenome-Wide Association Study
Contributors : Israel Fern ández-Cadenas ; Joan Montaner ; Natalia CullellSeries Type : Methylation profiling by arrayOrganism : Homo sapiensBackground and Purpose The neurological course after stroke is highly variable and is determined by demographic, clinical, and genetic factors. However, other heritable factors such as epigenetic DNA methylation could play a role in neurological changes after stroke. Methods We performed a three-stage epigenome-wide association study (EWAS) to evaluate DNA methylation associated with the difference between the National Institutes of Health Stroke Scale (NIHSS) at baseline and at disc...
Source: GEO: Gene Expression Omnibus - May 20, 2022 Category: Genetics & Stem Cells Tags: Methylation profiling by array Homo sapiens Source Type: research

Pharmacogenetics studies in stroke patients treated with rtPA: a  review of the most interesting findings
Pharmacogenomics, Ahead of Print.
Source: Future Medicine: Pharmacogenomics - October 26, 2021 Category: Genetics & Stem Cells Authors: Laia Lluci à-Carol Elena Mui ño Cristina Gallego-Fabrega Jara C árcel-Márquez Jesus Mart ín-Campos Miquel Lled ós Natalia Cullell Israel Fern ández-Cadenas Source Type: research

Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study
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Source: Epigenetics - April 5, 2020 Category: Genetics & Stem Cells Authors: Carolina Soriano-T árraga Uxue Lazcano Eva Giralt-Steinhauer Carla Avellaneda-G ómez Ángel Ois Ana Rodr íguez-Campello Elisa Cuadrado-Godia Alejandra G ómez-González Alba Fern ández-Sanlés Roberto Elosua Israel Fern ández-Cadenas Natalia Cullell Source Type: research

Sex Difference of Radiation Response in Occupational and Accidental Exposure
Conclusion and Outlook This review summarizes the data from major human studies on the health risks of radiation exposure and shows that sex can potentially influence the prolonged response to radiation exposure (Figure 1 and Tables 1, 2). These data suggest that long-term radiosensitivity in females is higher than that in males who receive a comparable dose of radiation. Our analysis of the literature agrees with the conclusions of the recent report on the Biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences (NAS), United States (National Research Council, 2006). The B...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research