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Drug: Insulin
Countries: Iran Health
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Total 174 results found since Jan 2013.
Propolis and its constituents against cardiovascular risk factors including obesity, hypertension, atherosclerosis, diabetes, and dyslipidemia: A comprehensive review
Iran J Basic Med Sci. 2023;26(8):853-871. doi: 10.22038/IJBMS.2023.67793.14835.ABSTRACTCardiovascular diseases (CVDs) are some of the major causes of death worldwide. The modern lifestyle elevates the risk of CVDs. CVDs have several risk factors such as obesity, dyslipidemia, atherosclerosis, hypertension, and diabetes. Using herbal and natural products plays a pivotal role in the treatment of different diseases such as CVDs, diabetes, and metabolic syndrome. Propolis, a natural resinous mixture, is made by honey bees. Its main components are phenolics and terpenoid compounds such as caffeic acid phenethyl ester, chrysin, ...
Source: Atherosclerosis - July 10, 2023 Category: Cardiology Authors: Arian Khoshandam AmirHossein Hedayatian AmirReza Mollazadeh Bibi Marjan Razavi Hossein Hosseinzadeh Source Type: research
The Effect of a Moderately Restricted Carbohydrate Diet on Cardiometabolic Risk Factors in Overweight and Obese Women With Metabolic Syndrome: A Randomized Controlled Trial
Clin Ther. 2023 Mar 3:S0149-2918(23)00063-2. doi: 10.1016/j.clinthera.2023.02.002. Online ahead of print.ABSTRACTPURPOSE: Metabolic syndrome (MetS) is a major public health concern that increases the risk of cardiovascular disease and mortality. In previous studies of MetS management, low-carbohydrate diets have been strongly emphasized, despite the fact that many apparently healthy individuals have difficulties adhering to these diets on a long-term basis. The purpose of the present study was to elucidate the effects of a moderately restricted carbohydrate diet (MRCD) on cardiometabolic risk factors in women with MetS.MET...
Source: Clinical Therapeutics - March 5, 2023 Category: Drugs & Pharmacology Authors: Seyed Mohammad Mousavi Hanieh-Sadat Ejtahed Fateme Ettehad Marvasti MinaSadat Taghavi Seyed Davar Siadat Shirin Hasani-Ranjbar Bagher Larijani Ahmad Esmaillzadeh Source Type: research
Relationship Between Genetic Polymorphisms in Cell Cycle Regulatory Gene TP53 and Polycystic Ovarian Syndrome: A Case-Control Study and In Silico Analyses
Biochem Genet. 2023 Mar 1. doi: 10.1007/s10528-023-10349-1. Online ahead of print.ABSTRACTPolycystic ovarian syndrome (PCOS) is a complex endocrine and metabolic condition with several potential causes. Insulin resistance is a hallmark of PCOS that often coexists with hirsutism, hyperandrogenism, being overweight, and hormonal imbalances. The functioning of multiple replication and transcription factors is regulated by tumor suppressor genes (TSGs), which play a crucial role in maintaining genomic integrity and controlling the cell cycle of granulosa cells. In the present study, we examined how three single nucleotide poly...
Source: Biochemical Genetics - March 1, 2023 Category: Genetics & Stem Cells Authors: Ghazaleh Biglari-Zadeh Saman Sargazi Malihe Mohammadi Marzieh Ghasemi Mahdi Majidpour Ramin Saravani Shekoufeh Mirinejad Source Type: research
"Ficus johannis Boiss. leaves ethanolic extract ameliorate streptozotocin-induced diabetes in rats by upregulating the expressions of GCK, GLUT4, and IGF and downregulating G6P"
This study investigated the pharmacological basis for antidiabetic effect of the ethanolic extract of F. johannis leaves using in vitro and in vivo experimental models. Qualitative screening of phytochemicals, estimation of total phenolic and flavonoid contents, and in vitro antioxidant and α-amylase inhibition assays were performed. Moreover, the High-performance liquid chromatography (HPLC) quantification, acute toxicity, glucose tolerance, and in vivo antidiabetic effect along with the evaluation of gene expressions involved in diabetes mellitus were carried out. Significant quantities of phenolic (71.208 ± 2.89 mgg-1...
Source: Environmental Science and Pollution Research International - February 11, 2023 Category: Environmental Health Authors: Afshan Asghar Ali Sharif Sana Javaid Awan Bushra Akhtar Muhammad Furqan Akhtar Sajid Ali None Shahnaz Source Type: research
Toxic reaction of a 3-year-old boy due to Hornet multiple stings in Kerman-Iran province: A case report
Toxicon. 2022 Nov 17:106976. doi: 10.1016/j.toxicon.2022.106976. Online ahead of print.ABSTRACTA three-year-old boy was attacked by a group of hornets and the head, arms, back and buttocks of the child were targeted to various stings. The child was first taken to a rural clinic and then to a hospital in Baft city. At arrival to rural clinic, the child was conscious and approximately 30 hyperpigmented, painful and itchy papular lesions was seen on his body. Head and neck weren't erythematous and edematous. However gradually, the face, lips, eyelids, and neck became swollen. The child became restless and itchy in the sting s...
Source: Toxicon - November 20, 2022 Category: Toxicology Authors: Gholamreza Sedighi Rouhullah Dehghani Masoomeh Varzandeh Source Type: research
