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Specialty: Drugs & Pharmacology
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Total 27 results found since Jan 2013.
Management of Dyslipidaemia for the Prevention of Stroke: Clinical Practice Recommendations from the Lipid Association of India
Curr Vasc Pharmacol. 2021 Nov 9. doi: 10.2174/1570161119666211109122231. Online ahead of print.ABSTRACTStroke is the second most common cause of death worldwide. The rates of stroke are increasing in less affluent countries predominantly because of a high prevalence of modifiable risk factors. The Lipid Association of India (LAI) has provided a risk stratification algorithm for patients with ischaemic stroke and recommended low density lipoprotein cholesterol (LDL-C) goals for those in a very high risk group and extreme risk group (category A) of <50 mg/dl (1.3 mmol/l) while the LDL-C goal for extreme risk group (catego...
Source: Current Vascular Pharmacology - November 9, 2021 Category: Drugs & Pharmacology Authors: Raman Puri Vimal Mehta S S Iyengar Padma Srivastava Jamal Yusuf Akshaya Pradhan Jeyaraj Durai Pandian Vijay K Sharma P N Renjen A Muruganathan K Mugundhan A V Srinivasan Sadanand Shetty S N Narasingan Devaki R Nair Manish Bansal D Prabhakar Mukul Varma Vi Source Type: research
Cost Effectiveness of Genotype-Guided Antiplatelet Therapy in Asian Ischemic Stroke Patients: Ticagrelor as an Alternative to Clopidogrel in Patients with CYP2C19 Loss of Function Mutations
ConclusionThis study suggests that it is cost effective to screen for LOF mutations in the CYP2C19 gene in ischemic stroke populations, with ticagrelor as a substitute for clopidogrel in those with LOF mutations.
Source: Clinical Drug Investigation - September 20, 2020 Category: Drugs & Pharmacology Source Type: research
Sovateltide: First Approval
This article summarizes the milestones in the development of sovateltide leading to this first approval for use in patients with ACIS.
Source: Drugs - July 24, 2023 Category: Drugs & Pharmacology Source Type: research
Clinical profile and role of C-reactive protein and lactate dehydrogenase as prognostic marker and comparative efficacy of different pharmacotherapeutic agents in patients with cerebrovascular accident: An observational study
Dibya Jyoti Sharma, K Jeenaleima Singha, Karuna Das, Chandrama Das, M RakeshIndian Journal of Pharmacology 2021 53(6):484-488
The current study was conducted to determine the role of C-reactive protein (CRP) and lactate dehydrogenase (LDH) as prognostic-marker and outcomes of different pharmacotherapeutic agents among patients with cerebrovascular accident (CVA). A hospital-based observational study was conducted and patients with CVA admitted were included. Serum-CRP on admission correlated positively with modified Rankin score (mRS) (r = 0.9, P < 0.001) in ischemic stroke, whereas no correlation be...
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Dibya Jyoti Sharma K Jeenaleima Singha Karuna Das Chandrama Das M Rakesh Source Type: research
Role of intravenous aspirin versus oral aspirin in the treatment of acute coronary syndrome: Answering a clinical query by systematic review and meta-analysis of randomized controlled trials
CONCLUSION: IV aspirin showed some advantages in terms of platelet aggregability biomarkers at 20 min and 1 week with comparable safety to oral aspirin. No difference was seen in terms of clinical outcomes (at 24 h, 7, and 30 days) and the occurrence of serious adverse events.
Source: Indian Journal of Pharmacology - June 7, 2023 Category: Drugs & Pharmacology Authors: Hardeep Kaur Phulen Sarma Anusuya Bhattacharyya Manojkumar Rohit Manisha Prajapat Subodh Kumar Ajay Prakash Bikash Medhi Source Type: research
Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats
Conclusions The MeCO exhibit potent cerebroprotective activity through its potent antioxidant and anti-inflammatory mechanisms, and hence may be useful in the management of ischemic stroke and associated complications. Graphical abstract
Source: Journal of Ethnopharmacology - May 26, 2018 Category: Drugs & Pharmacology Source Type: research
