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Vaccination: Cancer Vaccines
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Total 176 results found since Jan 2013.
COVID-19 Vaccine Concerns: Fact or Fiction?
Exp Clin Transplant. 2021 Mar 31. doi: 10.6002/ect.2021.0056. Online ahead of print.ABSTRACTOne year has elapsed since a team of Chinese scientists reported the first case of COVID-19 in Wuhan, China on January 8, 2020, after sequencing the first viral genetic material. Since then, many vaccines were rushed into testing, bypassing animal experimentations, with more than 200 pharma companies in different countries declaring the development of different vaccines, each with their own strategy for generating immunity, despite the arguments of many infectious disease experts that 18 months for a first vaccine is an incredibly a...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 20, 2021 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
A recombinant Chinese measles virus vaccine strain rMV-Hu191 inhibits human colorectal cancer growth through inducing autophagy and apoptosis regulating by PI3K/AKT pathway
In this study, the antitumor effects of rMV-Hu191 were evaluated in CRC both in vitro and in vivo. From our data, rMV-Hu191 induced remarkably caspase-dependent apoptosis and complete autophagy in vitro. In mice bearing CRC xenografts, tumor volume was remarkably suppressed and median survival was prolonged significantly with intratumoral treatment of rMV-Hu191. To gain further insight into the relationship of rMV-Hu191-induced apoptosis and autophagy, we utilized Rapa and shATG7 to regulate autophagy. Our data suggested that autophagy was served as a protective role in rMV-Hu191-induced apoptosis in CRC. PI3K/AKT signalin...
Source: Translational Oncology - April 13, 2021 Category: Cancer & Oncology Authors: Chu-di Zhang Yi-Long Wang Dong-Ming Zhou Meng-Ying Zhu Yao Lv Xiao-Qiang Hao Chu-Fan Qu Yi Chen Wei-Zhong Gu Ben-Qing Wu Pei-Chun Chen Zheng-Yan Zhao Source Type: research
High-quality reference genome for Clonorchis sinensis
Genomics. 2021 Mar 4:S0888-7543(21)00081-1. doi: 10.1016/j.ygeno.2021.03.001. Online ahead of print.ABSTRACTThe Chinese liver fluke, Clonorchis sinensis, causes the disease clonorchiasis, affecting ~35 million people in regions of China, Vietnam, Korea and the Russian Far East. Chronic clonorchiasis causes cholangitis and can induce a malignant cancer, called cholangiocarcinoma, in the biliary system. Control in endemic regions is challenging, and often relies largely on chemotherapy with one anthelmintic, called praziquantel. Routine treatment carries a significant risk of inducing resistance to this anthelmintic in the f...
Source: Genomics - March 7, 2021 Category: Genetics & Stem Cells Authors: Neil D Young Andreas J Stroehlein Liina Kinkar Tao Wang Woon-Mok Sohn Bill C H Chang Parwinder Kaur David Weisz Olga Dudchenko Erez Lieberman Aiden Pasi K Korhonen Robin B Gasser Source Type: research
Progress towards elimination of mother-to-child transmission of hepatitis B virus infection in China: a modelling analysis
CONCLUSION: Our results highlight how high-quality national data can be combined with modelling in monitoring the elimination of MTCT of HBV. By demonstrating the impact of increased interventions on target achievement dates, we anticipate that other high-burden countries will be motivated to strengthen HBV prevention policies.PMID:33658732 | PMC:PMC7924890 | DOI:10.2471/BLT.19.248146
Source: Bulletin of the World Health Organization - March 4, 2021 Category: International Medicine & Public Health Authors: Zheng Hui Shevanthi Nayagam Polin Chan Wang Fuzhen Mark Thursz Yin Zundong Miao Ning Sun Xiaojin Fuqiang Cui Zhang Guomin Timothy B Hallett Source Type: research
