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Focusing on single CT Perfusion quantitative maps: Percheron's artery stroke detection
Can J Neurol Sci. 2021 Jul 14:1-7. doi: 10.1017/cjn.2021.173. Online ahead of print.NO ABSTRACTPMID:34256884 | DOI:10.1017/cjn.2021.173
Source: The Canadian Journal of Neurological Sciences - July 14, 2021 Category: Neurology Authors: Tommaso Cillotto Giovanni Furlanis Alex Buoite Stella Carlo Lugnan Paola Caruso Roberta Pozzi Mucelli Marcello Naccarato Paolo Manganotti Source Type: research

CT Perfusion and EEG patterns in contrast-induced encephalopathy stroke mimic
Can J Neurol Sci. 2021 May 14:1-9. doi: 10.1017/cjn.2021.107. Online ahead of print.NO ABSTRACTPMID:33988107 | DOI:10.1017/cjn.2021.107
Source: The Canadian Journal of Neurological Sciences - May 14, 2021 Category: Neurology Authors: Giovanni Furlanis Paolo Manganotti Milo š Ajčević Jessica Rossi Chiara Vincenzi Marcello Naccarato Guido Bigliardi Andrea Zini Source Type: research

Nitroglycerin is Not Associated with Improved Cerebral Perfusion in Acute Ischemic Stroke.
PMID: 32799944 [PubMed - as supplied by publisher]
Source: The Canadian Journal of Neurological Sciences - August 16, 2020 Category: Neurology Authors: Kate M, Gioia L, Asdaghi N, Jeerakathil T, Shuaib A, Buck B, Emery D, Beaulieu C, Butcher K Tags: Can J Neurol Sci Source Type: research

Decompressive Craniectomy for Traumatic Brain Injury: Postoperative Cerebral Hemodynamic Evaluation
Conclusion: There is a wide heterogeneity of postoperative cerebral hemodynamic findings among TBI patients who underwent DC, including hemodynamic heterogeneity between their cerebral hemispheres. DC was proved to be effective for the treatment of cerebral oligoemia. Our data support the concept of heterogeneous nature of the pathophysiology of the TBI and suggest that DC as the sole treatment modality is insufficient. Introduction Decompressive craniectomy (DC) may effectively decrease intracranial pressure (ICP) and increase cerebral perfusion pressure (CPP) in traumatic brain injury (TBI) patients with refracto...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Characterizing the Penumbras of White Matter Hyperintensities and Their Associations With Cognitive Function in Patients With Subcortical Vascular Mild Cognitive Impairment
Conclusion In this study, reduced CBF and FA and increased MD in the inner NAWM layers for both PVWMH and DWMH suggested extensive WM alterations beyond the visible WM lesions commonly observed on clinical MRI of svMCI subjects. CBF penumbras cover more extensive WM at risk than DTI penumbras, suggesting the likelihood that compromised CBF precedes white matter integrity changes, and CBF penumbras may be a potential target for the prevention of further microstructural white matter damage. The imaging parameters investigated, however, did not correlate to cognition. Author Contributions YZ, QX, and XG conceived and desig...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Decompressive Craniectomy for Traumatic Brain Injury: Postoperative TCD Cerebral Hemodynamic Evaluation
Conclusion: There is a wide heterogeneity of postoperative cerebral hemodynamic findings among TBI patients who underwent DC, including hemodynamic heterogeneity between their cerebral hemispheres. DC was proved to be effective for the treatment of cerebral oligoemia. Our data support the concept of heterogeneous nature of the pathophysiology of the TBI and suggest that DC as the sole treatment modality is insufficient. Introduction Decompressive craniectomy (DC) may effectively decrease intracranial pressure (ICP) and increase cerebral perfusion pressure (CPP) in traumatic brain injury (TBI) patients with refracto...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

The 2018 ter Brugge Lecture: Problems with the Introduction of Innovations in Neurovascular Care.
Abstract Most endovascular innovations have been introduced into clinical care by showing good outcomes in small enthusiastic case series of selected patients. Randomized clinical trials (RCTs) have rarely been performed, except for acute ischemic stroke, but even then most trial designs were too explanatory to inform clinical decisions. In this article, we review 2 × 2 tables and forest plots that summarize RCT results to examine methodological issues in the design and interpretation of clinical studies. Research results can apply in practice when RCTs are all-inclusive, pragmatic trials. Common problems inclu...
Source: The Canadian Journal of Neurological Sciences - February 21, 2019 Category: Neurology Authors: Raymond J, Fahed R, Roy D, Darsaut TE Tags: Can J Neurol Sci Source Type: research