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Vaccination: Malaria Vaccine
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Total 1933 results found since Jan 2013.
Elimination Strategy for Malaria in El Salvador: a Retrospective Study
This study retrospectively investigated the evolution of strategies utilized to reduce malaria incidence and eliminate it in El Salvador. A retrospective systematic review of the malaria cases from 1960 until 2019 was carried out by analyzing the data from the MOH surveillance system, as well as a historical analysis of documents from El Salvador MOH, PAHO/WHO, and UN El Salvador Malaria Eradication Program since its origin in the 1950s.Recent FindingsThe peak of malaria cases in the country was observed in 1980 with 95,835 cases when the Civil War started with a subsequent decline reaching 0 indigenous cases in 2017, 2018...
Source: Current Tropical Medicine Reports - September 18, 2023 Category: Tropical Medicine Source Type: research
Baseline immune states (BIS) associated with vaccine responsiveness and factors that shape the BIS
Semin Immunol. 2023 Sep 15;70:101842. doi: 10.1016/j.smim.2023.101842. Online ahead of print.ABSTRACTVaccines are among the greatest inventions in medicine, leading to the elimination or control of numerous diseases, including smallpox, polio, measles, rubella, and, most recently, COVID-19. Yet, the effectiveness of vaccines varies among individuals. In fact, while some recipients mount a robust response to vaccination that protects them from the disease, others fail to respond. Multiple clinical and epidemiological factors contribute to this heterogeneity in responsiveness. Systems immunology studies fueled by advances in...
Source: Seminars in Immunology - September 17, 2023 Category: Allergy & Immunology Authors: Djamel Nehar-Belaid Mark Sokolowski Sathyabaarathi Ravichandran Jacques Banchereau Damien Chaussabel Duygu Ucar Source Type: research
Decoding the invasive nature of a tropical pathogen of concern: The invasive non-Typhoidal Salmonella strains causing host-restricted extraintestinal infections worldwide
Microbiol Res. 2023 Sep 12;277:127488. doi: 10.1016/j.micres.2023.127488. Online ahead of print.ABSTRACTInvasive-Non-Typhoidal Salmonella (iNTS) are the major cause of health concern in the low-income, under-developed nations in Africa and Asia that lack proper sanitation facilities. Around 5% of the NTS cases give rise to invasive, extraintestinal diseases leading to focal infections like osteomyelitis, meningitis, osteoarthritis, endocarditis and neonatal sepsis. iNTS serovars like S. Typhimurium, S. Enteritidis, S. Dublin, S. Choleraesuis show a greater propensity to become invasive than others which hints at the geneti...
Source: Cell Research - September 16, 2023 Category: Cytology Authors: Dipasree Hajra Abhilash Vijay Nair Dipshikha Chakravortty Source Type: research
Too Many Mothers Are Dying in Childbirth. Here ’s How They Can Be Saved
With recent reports of difficult pregnancies and births from celebrities like Beyonce, Serena Williams, and Alyson Felix, and the death of Olympian Tori Bowie during childbirth, the long-overlooked dangers of maternal and child mortality have become increasingly prominent.
In a new report published by the Bill & Melinda Gates Foundation, the global health philanthropic group highlights lagging progress in achieving United Nations (UN) goals for lowering mother and child deaths, along with innovative ways of addressing the problems with relatively inexpensive and easy to implement solutions that the group projects co...
Source: TIME: Health - September 12, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthscienceclimate Source Type: news
At UNGA, Civil Society Must Mobilize Global Solidarity for Universal Health Coverage
By ,
Founding Executive Director, African Center for Global Health and Social TransformationcbalesSeptember 12, 2023September 12, 2023 12:00 PMAs world leaders prepare for the United Nations General Assembly (UNGA) in New York, it ’s important for those of us in civil society to prepare ourselves ideologically to engage, especially for pushing leaders to make commitments during the UN High-Level Meeting on Universal Health Coverage (UHC) on September 21. The theme for this important gathering is Universal health coverage: expanding our ambition for health and well-being in a post-COVID world.We all have a right to ...
Source: IntraHealth International - September 12, 2023 Category: International Medicine & Public Health Authors: cbales Source Type: news
Hiding in plain sight: an epitope-based strategy for a subunit malaria vaccine
Trends Parasitol. 2023 Sep 6:S1471-4922(23)00197-6. doi: 10.1016/j.pt.2023.08.006. Online ahead of print.ABSTRACTRecent data suggest that approaches to developing a subunit blood-stage malaria vaccine may be misdirected. While antigenic polymorphism is recognized as a challenge, efforts to counter this have primarily involved enhancing the quantity and quality of antibody with potent adjuvants, identifying conserved target proteins, or combining multiple antigens to broaden the immune response. However, paradoxically, evidence has emerged that narrowing, rather than broadening, the immune response may be required to obtain...
Source: Trends in Parasitology - September 8, 2023 Category: Parasitology Authors: Michael F Good Stephanie K Yanow Source Type: research
THE HEALTH SYSTEM OF THE FIRST CZECHOSLOVAK REPUBLIC AND ITS ROLE IN COMBATING CONTAGIOUS DISEASES IMMEDIATELY AFTER THE FIRST WORLD WAR (THE 1920s)
Conclusion: The systematic development of new legislation contributed to the new Republic's proficiency at the task and the gradual reduction in the number of infectious diseases.PMID:37667608
Source: Medical History - September 5, 2023 Category: History of Medicine Authors: El żbieta Tabor Kamil Tabor Wojciech Pluskiewicz Source Type: research
