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Total 174 results found since Jan 2013.

A Case of Pathological Complete Response and Resolution of Dermatomyositis Following Neoadjuvant Chemotherapy in HER2-Positive Early Breast Cancer
Discussion and conclusion. Similar cases in literature are commonly referred to a first-line surgery and the role of neoadjuvant chemotherapy is debatable.PMID:34073827 | PMC:PMC8161769 | DOI:10.3390/curroncol28030182
Source: Current Oncology - June 2, 2021 Category: Cancer & Oncology Authors: Marta Piras Martina Panebianco Matteo Garibaldi Michela Roberto Gioia Merlonghi Patrizia Pellegrini Paolo Marchetti Source Type: research

A Swine Hind Limb Ischemia Model Useful for Testing Peripheral Artery Disease Therapeutics
AbstractCurrently, there is no large animal model of sustained limb ischemia suitable for testing novel angiogenic therapeutics for peripheral artery disease (PAD) such as drugs, genes, materials, or cells. We created a large animal model suitable for efficacy assessment of these therapies by testing 3 swine hind limb ischemia (HLI) variations and quantifying vascular perfusion, muscle histology, and limb function. Ligation of the ipsilateral external and bilateral internal iliac arteries produced sustained gait dysfunction compared to isolated external iliac or unilateral external and internal iliac artery ligations. Hype...
Source: Journal of Cardiovascular Translational Research - May 28, 2021 Category: Cardiology Source Type: research

Avascular femoral necrosis as part of Cushing syndrome presentation: a  case report
ConclusionIn some cases, CS signs may go unnoticed and the diagnosis postponed. Avascular necrosis is a rare presenting feature of endogenous hypercortisolism, and, if left untreated, complete collapse of the femoral head may ensue, rendering the need for hip replacement in up to 70% of patients. Suspicion and recognition of atypical features is therefore important in avoiding complications and delay in treatment of CS.
Source: Journal of Medical Case Reports - May 26, 2021 Category: General Medicine Source Type: research

Axial muscle weakness and the rimmed vacuoles in muscle histology in inflammatory myopathy with anti-ku antibody: a case report
Scand J Rheumatol. 2021 May 5:1-3. doi: 10.1080/03009742.2021.1894825. Online ahead of print.NO ABSTRACTPMID:33949908 | DOI:10.1080/03009742.2021.1894825
Source: Scandinavian Journal of Rheumatology - May 5, 2021 Category: Rheumatology Authors: L Qiao R Ban Q Shi Source Type: research