Filtered By:
Therapy: Gene Therapy
Nutrition: Iron
This page shows you your search results in order of date.
Order by Relevance | Date
Total 49 results found since Jan 2013.
A shift in focus towards precision oncology, driven by revolutionary nanodiagnostics; revealing mysterious pathways in colorectal carcinogenesis
This article examines current nanomedicine patents for CRC, including the work of Delta-Fly, Merrimack, and Pfenning, Meaning & Partner, among others. In terms of future nanomedicine research and development, ligand production, particle size, and clearance are crucial factors. Lastly, the numerous nanostructures utilized in nanomedicine for targeted drug administration and diagnostics indicate optimistic prospects for enhancing CRC treatment. The successes of nanomedicine research and development for existing colon cancer treatments are also highlighted in this review.PMID:37650995 | DOI:10.1007/s00432-023-05331-8
Source: Clinical Colorectal Cancer - August 31, 2023 Category: Cancer & Oncology Authors: Satyam Sharma Sankha Bhattacharya Kajal Joshi Sanjiv Singh Source Type: research
Cellular and animal models for the investigation of β-thalassemia
Blood Cells Mol Dis. 2023 May 30:102761. doi: 10.1016/j.bcmd.2023.102761. Online ahead of print.ABSTRACTβ-Thalassemia is a genetic form of anemia due to mutations in the β-globin gene, that leads to ineffective and extramedullary erythropoiesis, abnormal red blood cells and secondary iron-overload. The severity of the disease ranges from mild to lethal anemia based on the residual levels of globins production. Despite being a monogenic disorder, the pathophysiology of β-thalassemia is multifactorial, with different players contributing to the severity of anemia and secondary complications. As a result, the identificatio...
Source: Blood Cells, Molecules and Diseases - June 4, 2023 Category: Hematology Authors: Antonella Nai Celia Cordero-Sanchez Emanuele Tanzi Alessia Pagani Laura Silvestri Simona Maria Di Modica Source Type: research
Cell-Based Gene Therapy for b-Thalassemia
Indian Pediatr. 2023 Apr 15;60(4):313-316.ABSTRACTThe United States Food and Drug Administration (FDA) approved betibeglogene autotemcel (beti-cel), the first cell-based gene therapy for adult and pediatric patients with b-thalassemia in August, 2022. This update details this and other novel therapies that have emerged in the treatment of b-thalassemia, apart from transfusion and iron chelation, with particular focus on newly approved gene therapy.PMID:37002845
Source: Indian Pediatrics - April 1, 2023 Category: Pediatrics Authors: Yajika Arya Puneet Kaur Sahi Source Type: research
Therapeutic Effects of Mesenchymal Stem Cells Expressing Erythropoietin on Cancer-Related Anemia in Mice Model
CONCLUSIONS: Data indicated that rhWJMSCs-EPO increased the circulating level of EPO, Hb, and Hct in both mouse subject groups, and improved the anemia of cancer in both cancer-free and cancerous mice.PMID:35382717 | DOI:10.2174/1566523222666220405134136
Source: Herpes - April 6, 2022 Category: Infectious Diseases Authors: Mohammad Estiri Bahareh Estiri Asghar Fallah Marziyeh Aghazadeh Amir Sedaqati Abbas Abdollahi Mahsa Rabienia Nahid Mortazavidehkordi Akbar Farjadfar Source Type: research
