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Medical adjuvant treatment to increase patency of arteriovenous fistulae and grafts
CONCLUSIONS: The meta-analyses of three studies for ticlopidine (an antiplatelet treatment), which all used the same dose of treatment but with a short follow-up of only one month, suggest ticlopidine may have a beneficial effect as an adjuvant treatment to increase the patency of AVFs and AVGs in the short term. There was insufficient evidence to determine if there was a difference in graft patency between placebo and other treatments such as aspirin, fish oil, clopidogrel, dipyridamole, dipyridamole plus aspirin, warfarin, sulphinpyrazone and GTN patch. The certainty of the evidence was low to moderate due to short follo...
Source: Cochrane Database of Systematic Reviews - July 23, 2021 Category: General Medicine Authors: Imran Mohamed Mohamad Fathul Aizat Kamarizan Antonio Da Silva Source Type: research

Stakeholder Perspectives on Factors Related to Deprescribing Potentially Inappropriate Medications in Older Adults Receiving Dialysis
CONCLUSIONS: Challenges to integration of deprescribing into dialysis clinics included siloed health systems, time constraints, co-management behaviors, and clinician and patient knowledge and attitudes towards deprescribing.PMID:37499693 | DOI:10.2215/CJN.0000000000000229
Source: Clinical Journal of the American Society of Nephrology : CJASN - July 27, 2023 Category: Urology & Nephrology Authors: Rasheeda K Hall Jeanette Rutledge Anika Lucas Christine K Liu Jennifer St Clair Russell Wendy St Peter Laura J Fish Cathleen Col ón-Emeric Source Type: research

The pathogenesis of hemodialysis vascular access failure and systemic therapies for its prevention: Optimism unfulfilled
Abstract In patients receiving hemodialysis, the provision of safe and effective vascular access using an arteriovenous fistula or graft is regarded as a critical priority by patients and health professionals. Vascular access failure is associated with morbidity and mortality, such that strategies to prevent these outcomes are essential. Inadequate vascular remodeling and neointimal hyperplasia resulting in stenosis and frequently thrombosis are critical to the pathogenesis of access failure. Systemic medical therapies with pleiotropic effects including antiplatelet agents, omega‐3 polyunsaturated fatty acids (fish oils)...
Source: Seminars In Dialysis - November 1, 2017 Category: Hematology Authors: Andrea K Viecelli, Trevor A Mori, Prabir Roy ‐Chaudhury, Kevan R Polkinghorne, Carmel M Hawley, David W Johnson, Elaine M Pascoe, Ashley B Irish Tags: REVIEW ARTICLE Source Type: research

The pathogenesis of hemodialysis vascular access failure and systemic therapies for its prevention: Optimism unfulfilled.
Abstract In patients receiving hemodialysis, the provision of safe and effective vascular access using an arteriovenous fistula or graft is regarded as a critical priority by patients and health professionals. Vascular access failure is associated with morbidity and mortality, such that strategies to prevent these outcomes are essential. Inadequate vascular remodeling and neointimal hyperplasia resulting in stenosis and frequently thrombosis are critical to the pathogenesis of access failure. Systemic medical therapies with pleiotropic effects including antiplatelet agents, omega-3 polyunsaturated fatty acids (fis...
Source: Seminars in Dialysis - November 26, 2017 Category: Urology & Nephrology Authors: Viecelli AK, Mori TA, Roy-Chaudhury P, Polkinghorne KR, Hawley CM, Johnson DW, Pascoe EM, Irish AB Tags: Semin Dial Source Type: research

Omega-3 Fatty Acids Improve Chronic Kidney Disease-Associated Pruritus and Inflammation
Conclusion: Omega-3 PUFA supplementation improved inflammation, renal function, cardiovascular parameters, dry skin conditions, and the consequent symptoms of pruritus in hemodialysis patients.PMID:35744059 | PMC:PMC9229849 | DOI:10.3390/medicina58060796
Source: Medicina (Kaunas) - June 24, 2022 Category: Universities & Medical Training Authors: Ya-Ling Lin Chia-Liang Wang Kai-Li Liu Cheng-Nan Yeh Tsay-I Chiang Source Type: research

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