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Therapy: Chemotherapy
Nutrition: Calcium
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Total 269 results found since Jan 2013.
Serum basic fibroblast growth factor and interleukin-1 β predict the effect of first-line chemotherapy in patients with advanced gastric cancer
CONCLUSION: The FLOT regimen was effective in reducing the serum CEA, CA199, and TPS levels as well as in improving the 1-year survival rate of patients with good tolerability, making it worthy of clinical promotion and application.PMID:37731570 | PMC:PMC10507556 | DOI:10.12998/wjcc.v11.i26.6083
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Li Zheng Li-Hong Gan Ling Yao Bin Li Ya-Qin Huang Fu-Bao Zhang Meng-Qi Kuang Nian Fang Source Type: research
Inhibition of C5aR1 as a promising approach to treat taxane-induced neuropathy
In conclusion, C5aR1 inhibition is proposed as a therapeutic option with the potential to exert long-term protective effect on PIPN-associated neuropathic pain and inflammation.PMID:37722320 | DOI:10.1016/j.cyto.2023.156370
Source: Cytokine - September 18, 2023 Category: Molecular Biology Authors: C Cristiano C Giorgio P Cocchiaro S Boccella M C Cesta V Castelli F M Liguori M R Cuozzo L Brandolini R Russo M Allegretti Source Type: research
Calcium signals and potential therapy targets in ovarian cancer (Review)
Int J Oncol. 2023 Nov;63(5):125. doi: 10.3892/ijo.2023.5573. Epub 2023 Sep 15.ABSTRACTOvarian cancer (OC) is a deadly disease. The poor prognosis and high lethality of OC are attributed to its high degrees of aggressiveness, resistance to chemotherapy and recurrence rates. Calcium ion (Ca2+) signaling has received attention in recent years, as it appears to form an essential part of various aspects of cancer pathophysiology and is a potential therapeutic target for OC treatment. Disruption of normal Ca2+ signaling pathways can induce changes in cell cycle progression, apoptosis, proliferation and migration and invasion, le...
Source: International Journal of Oncology - September 15, 2023 Category: Cancer & Oncology Authors: Fengying Deng Mengyu Fu Chenxuan Zhao Jiahui Lei Ting Xu Bingyu Ji Hongmei Ding Yueming Zhang Jie Chen Junlan Qiu Qinqin Gao Source Type: research
Efficacy and safety of drug therapy for the prevention and treatment of chemotherapy-induced peripheral neuropathy: a protocol for a systematic review and network meta-analysis
This article describes a protocol for evaluating the efficacy and safety of drug therapy for the prevention and treatment of CIPN. The results of the proposed systematic review with network meta-analysis (NMA) will provide new insights into the prevention and treatment of CIPN.
Methods and analysis
We will conduct a literature search in MEDLINE, PubMed, Embase, Cochrane Central Register of Controlled Trials and ClinicalTrials.gov to find relevant articles published through January 2023. We will include studies that investigated the efficacy and safety of vitamin B12, goshajinkigan, non-steroidal anti-inflammatory analgesi...
Source: BMJ Open - September 12, 2023 Category: General Medicine Authors: Sato, M. T., Hasegawa, T., Noma, H., Sugita, H., Ota, E. Tags: Open access, Oncology Source Type: research
Effect of chemotherapy and different chemotherapy regimens on bone health among Chinese breast cancer women in different menstrual status: a self-control study
CONCLUSION: Chemotherapy might induce lumbar vertebrae BMD loss and spine osteoporosis with regimen differences among Chinese BC patients. Calcium/VitD supplementation could improve bone turnover markers, bone metabolism indicators, and bone mineral density. Early interventions on bone health are needed for BC patients during chemotherapy.PMID:37642751 | DOI:10.1007/s00520-023-07960-8
Source: Cancer Control - August 29, 2023 Category: Cancer & Oncology Authors: Bai-Qing Peng Juan Wu Shen Tian Xiu-Quan Qu Xin-Yu Liang Jun-Han Feng Yu-Ling Chen Rui-Ling She Chen-Yu Ma Jing-Yu Song Zhao-Xing Li Zhi-Yu Jiang Kai-Nan Wu Ling-Quan Kong Source Type: research
A re-consideration of neural/receptor mechanisms in chemotherapy-induced nausea and vomiting: current scenario and future perspective
Pharmacol Rep. 2023 Aug 16. doi: 10.1007/s43440-023-00514-z. Online ahead of print.ABSTRACTThe neural mechanisms and the receptors behind the course of chemotherapy-induced nausea and vomiting (CINV) are well described and considered mechanistically multifactorial, whereas the neurobiology of nausea is not completely understood yet. Some of the anti-neoplastic medications like cisplatin result in biphasic vomiting response. The acute phase of vomiting is triggered mainly via the release of serotonin from the enterochromaffin (EC) cells in the gastrointestinal tract (GIT) and results in stimulation of dorsal vagal complex (...
Source: Pharmacological Reports - August 16, 2023 Category: Drugs & Pharmacology Authors: Ihsan Ullah Muhammad Ayaz Source Type: research
