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Specialty: Urology & Nephrology
Nutrition: Calcium
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Total 2043 results found since Jan 2013.
Efficacy and Safety of Upacicalcet in Hemodialysis Patients with Secondary Hyperparathyroidism: A Randomized Placebo-Controlled Trial
CONCLUSIONS: Upacicalcet, a novel injectable calcimimetic, is effective and safe for secondary hyperparathyroidism patients receiving HD.CLINICAL TRIAL REGISTRY NAME AND REGISTRATION NUMBER: Phase 3 Study of SK-1403, NCT03801980.PMID:37696667 | DOI:10.2215/CJN.0000000000000253
Source: Clinical Journal of the American Society of Nephrology : CJASN - September 11, 2023 Category: Urology & Nephrology Authors: Takashi Shigematsu Fumihiko Koiwa Yoshitaka Isaka Masafumi Fukagawa Keiko Hagita Yukihisa S Watanabe Daisuke Honda Tadao Akizawa Source Type: research
Coupling of renal sodium and calcium transport: A modeling analysis of transporter inhibition and sex differences
Am J Physiol Renal Physiol. 2023 Aug 24. doi: 10.1152/ajprenal.00145.2023. Online ahead of print.ABSTRACTCalcium (Ca2+) transport along the nephron occurs via specific transcellular and paracellular pathways, and is coupled to the transport of other electrolytes. Notably sodium (Na+) transport establishes an electrochemical gradient to drive Ca2+ reabsorption. Hence, alterations in renal Na+ handling, under pathophysiological conditions or pharmacological manipulations, can have major effects on Ca2+ transport. An important class of pharmacological agent is diuretics, which are commonly prescribed for the management of blo...
Source: Am J Physiol Renal P... - August 24, 2023 Category: Urology & Nephrology Authors: Shervin Hakimi Pritha Dutta Anita T Layton Source Type: research
Sodium zirconium cyclosilicate reconciles management of hyperkalemia and continuity of renin-angiotensin-aldosterone system inhibitors: a retrospective observational study
CONCLUSIONS: Our study suggests that administering sodium zirconium cyclosilicate to patients with hyperkalemia allows for a higher continuation rate of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers than calcium polystyrene sulfonate. These findings suggest that sodium zirconium cyclosilicate has potential benefits for patients with chronic kidney disease receiving renin-angiotensin-aldosterone system inhibitors.PMID:37608241 | DOI:10.1007/s40620-023-01743-4
Source: Journal of Nephrology - August 23, 2023 Category: Urology & Nephrology Authors: Wakana Kimura Shun Minatoguchi Tomohiro Mizuno Shigehisa Koide Hiroki Hayashi Midori Hasegawa Daijo Inaguma Naotake Tsuboi Source Type: research
Renal sarcoidosis presenting with chronic kidney disease and hypercalcemia
We describe a 72-year-old male who presented with chronic kidney disease and elevated serum calcium and angiotensin-converting enzyme. Renal biopsy pathology showed chronic granulomatous interstitial nephritis. Renal function was significantly improved after glucocorticoid therapy. This case emphasizes that chronic kidney disease and hypercalcemia can be clues for renal sarcoidosis. Early renal biopsy and projective treatment is beneficial for renal outcome.PMID:37548467 | DOI:10.5414/CN111115
Source: Clinical Nephrology - August 7, 2023 Category: Urology & Nephrology Authors: Yuanyuan Wang Feng Du Hua Zhou Source Type: research
Blood pressure management and long-term outcomes in kidney transplantation: a holistic view over a 35-year period
CONCLUSIONS: Pharmacological recommendations and sodium intake reduction are poorly respected, but even when respected, do not result in better blood pressure control, or patient or graft survival. Uncontrolled blood pressure, not the use of specific antihypertensive classes, is associated with reduced patient, and to a lesser extent, reduced graft survival, even using the 120/80 mmHg cut-off.PMID:37548826 | DOI:10.1007/s40620-023-01706-9
Source: Journal of Nephrology - August 7, 2023 Category: Urology & Nephrology Authors: Lionel Tchatat Wangueu Jean-Baptiste de Fr éminville Philippe Gatault Matthias Buchler H élène Longuet Theodora Bejan-Angoulvant Benedicte Sautenet Jean-Michel Halimi Source Type: research
Renal sarcoidosis presenting with chronic kidney disease and hypercalcemia
We describe a 72-year-old male who presented with chronic kidney disease and elevated serum calcium and angiotensin-converting enzyme. Renal biopsy pathology showed chronic granulomatous interstitial nephritis. Renal function was significantly improved after glucocorticoid therapy. This case emphasizes that chronic kidney disease and hypercalcemia can be clues for renal sarcoidosis. Early renal biopsy and projective treatment is beneficial for renal outcome.PMID:37548467 | DOI:10.5414/CN111115
Source: Clinical Nephrology - August 7, 2023 Category: Urology & Nephrology Authors: Yuanyuan Wang Feng Du Hua Zhou Source Type: research
Blood pressure management and long-term outcomes in kidney transplantation: a holistic view over a 35-year period
CONCLUSIONS: Pharmacological recommendations and sodium intake reduction are poorly respected, but even when respected, do not result in better blood pressure control, or patient or graft survival. Uncontrolled blood pressure, not the use of specific antihypertensive classes, is associated with reduced patient, and to a lesser extent, reduced graft survival, even using the 120/80 mmHg cut-off.PMID:37548826 | DOI:10.1007/s40620-023-01706-9
Source: Journal of Nephrology - August 7, 2023 Category: Urology & Nephrology Authors: Lionel Tchatat Wangueu Jean-Baptiste de Fr éminville Philippe Gatault Matthias Buchler H élène Longuet Theodora Bejan-Angoulvant Benedicte Sautenet Jean-Michel Halimi Source Type: research
