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Risk Factors for Recurrence of Nasal Polyps after Endoscopic Sinus Surgery in Patients with Allergic Chronic Rhino Sinusitis
AbstractRhino sinusitis, is a common inflammatory disease that affects the nasal cavity and paranasal sinuses in millions of individuals. Chronic sinusitis patients complain of a combination of nasal obstruction, rhinorrhea, post nasal drip and facial pain. To identify the risk factors of the recurrence of nasal polyps in chronic rhino sinusitis patients after endoscopic sinus surgery. After a review of 60 patients with chronic rhino sinusitis with failed medical treatment requiring FESS presenting in Kasr Alainy Hospital in Cairo University and October 6 University Hospital from May 2022 to March 2023. All patients were s...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - June 23, 2023 Category: ENT & OMF Source Type: research

Association of Adenoid Hypertrophy with Nasal and Middle Ear Pathologies in Adults
AbstractA prospective comparative study was carried out in patients attending ENT Out Patient Department of a tertiary care Hospital with an aim to determine the association of adenoid hypertrophy with chronic nasal and middle ear pathologies in those aged 18  years or above. Patients presenting between August 2020 and February 2022 with chronic nasal and middle ear pathologies who underwent diagnostic nasal endoscopy were seen for adenoid hypertrophy and its association was analysed statistically. Adenoid hypertrophy (AH) in 18–25, 26–35, 36–45 a nd 46–55 years age group are 56.25, 28.12, 12.5, 3.125% respective...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - June 7, 2023 Category: ENT & OMF Source Type: research

New STELARA ® (ustekinumab) Long-Term Data Support its Established Safety Profile in Inflammatory Bowel Disease and Durable Efficacy in Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, March 4, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced final pooled long-term safety results for STELARA® (ustekinumab) through five years in adults with moderately to severely active Crohn’s disease (CD) and four years in adults with moderately to severely active ulcerative colitis (UC), as well as final four-year clinical and endoscopic outcomes from the UNIFI long-term extension (LTE) study evaluating the efficacy of STELARA for the treatment of adults with moderately to severely active UC.1,2 These data are a part of Janssen’s 22 oral and poster ...
Source: Johnson and Johnson - March 4, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Janssen Presents Study Results Showing Clinical Efficacy for TREMFYA ® (guselkumab) and Long-Term Safety Profile for STELARA® (ustekinumab) for Patients Living with Inflammatory Bowel Disease at Digestive Disease Week® 2022
SPRING HOUSE, PENNSYLVANIA, May 24, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from the Phase 2 GALAXI 1 clinical trial of TREMFYA® (guselkumab) in adult patients with moderately to severely active Crohn’s disease (CD), and from three separate long-term pooled analyses of adult patients with ulcerative colitis (UC) and CD treated with STELARA® (ustekinumab).1,2,3,4 These data are being presented as oral and poster presentations and are among 29 Janssen abstracts presented during the Digestive Disease Week® (DDW) meeting taking place in person and virtually in San Di...
Source: Johnson and Johnson - May 24, 2022 Category: Pharmaceuticals Source Type: news

What Are Common Gastrointestinal Polyposes in Children?
Discussion Bloody stools or blood in the diaper is a relatively common complaint in general pediatrics. For most patients it is often a minor concern. Commonly it is a transient problem (e.g. rectal fissure caused by constipation or trauma) or often not blood (e.g. urate crystals in the diaper, food, menses, etc.). Real blood does occur with an identifiable cause such as long distance running or heavy exercise, or milk protein allergy/sensitivity that improves with a milk-restricted diet. Many more serious causes are associated with heavier or more recalcitrant bleeding, increased defecation, abdominal pain, poor eating an...
Source: PediatricEducation.org - January 24, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Janssen Presents Results of First Head-to-Head Study of Biologic Therapies in Patients with Moderate to Severe Crohn ’s Disease
SPRING HOUSE, PENNSYLVANIA, May 23, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced efficacy and safety data for STELARA® (ustekinumab) in Crohn’s disease (CD) and ulcerative colitis (UC),1-4including data from the SEAVUE study, the first head-to-head study of biologic therapies in patients with CD, presented in a Clinical Science Late-Breaking Abstract Plenary session.1 SEAVUE data showed treatment with STELARA demonstrated high rates of clinical remission, corticosteroid-free remission, clinical response and endoscopic response through one year in biologic-naïve patients with mo...
Source: Johnson and Johnson - May 24, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

The Human Experience: How Patients Inspire Innovation and Why Medtech Should Listen
Discussions centered on patient-centered, outward-looking technology with an emphasis on data and patient engagement. The medtech CEO, physician, and hospital executive all consider innovation differently, but they all have the patient as the muse. What Patient-Inspired Innovation Means Todd Dunn, innovation director for Intermountain Healthcare, said during a conference panel that his organization created a new initiative to put empathy at the forefront of innovation. He said Proctor & Gamble's "immersion research," where executives spend time in people's homes to understand what matters to them, inspired him to appro...
Source: MDDI - September 30, 2017 Category: Medical Devices Authors: Heather R. Johnson Tags: Medical Device Business Source Type: news

Gastric anisakiasis
A 63-year-old man presented to the emergency department with a 1-day history of acute onset severe epigastric abdominal pain and nausea several hours after eating raw mackerel at a sushi restaurant. His symptoms persisted, and he was admitted to the hospital on the following day. He had no previous cardiovascular or gastrointestinal problems, and he denied any history of an allergy. His vital signs were normal. On physical examination, he exhibited mild tenderness of his epigastrium without guarding or rebound tenderness. The complete blood examination, including an eosinophil count and blood chemistry, was unremarkable. A...
Source: QJM - January 6, 2017 Category: Internal Medicine Source Type: research

Celiac disease: 5 things parents need to know
Dr. Dascha Weir, associate director, Boston Children’s Celiac Disease Program It may be difficult for parents to hear that their child has a chronic illness. When the diagnosis is celiac disease (CD), an autoimmune disorder caused by an intolerance to gluten, there is good news. CD is treatable by changes in diet. How it works: When food enters the stomach, it’s broken down into tiny digestible particles, which then travel through the small intestine. The small intestine is lined with villi — tiny finger-like projections that absorb nutrients from the food passing through. In celiac disease, gluten, which is a pro...
Source: Thrive, Children's Hospital Boston - September 28, 2016 Category: Pediatrics Authors: Maureen McCarthy Tags: Diseases & Conditions celiac disease Dr. Dascha Weir gluten intolerance Source Type: news

SNOT-22 Validation in Greek Patients
Background: Chronic rhinosinusitis (CRS) with or without nasal polyps is a frequent and significant health problem. The 22-item Sinonasal Outcome Test (SNOT-22) is a valid, disease-specific health status instrument translated into several languages. The translation into Greek has been considered essential for the individual assessment of the patients' symptoms and a reliable tool for quality of life evaluation. Methods: Our study included 40 patients with CRS without nasal polyps and 40 healthy individuals as control group recruited from the ENT Allergy and Endoscopy Clinic of Chania General Hospital. Assessment included f...
Source: ORL - November 6, 2014 Category: ENT & OMF Source Type: research

Influence of allergy and bacterial colonization on the quality of life in nasal polyposis patients.
Abstract Allergies and bacterial colonization are frequently found in patients with chronic rhinosinuitis with nasal polyposis (CRSwNP). The aim of this study was to identify patients with allergy and present microorganisms in ethmoid sinus among the patients with refractory CRSwNP undergoing surgical treatment at the University Hospital Centre Osijek, and to compare their life quality, defined by SNOT-20 analysis (sinonasal outcome test) to the rest of patients, and a control group consisting of patients undergoing septoplasty but free of allergy and/or CRS. An additional aim was to identify specific types and st...
Source: Collegium Antropologicum - December 1, 2013 Category: Epidemiology Authors: Mihalj H, Loncar MB, Mihalj M, Zubcić Z, Vceva A, Bujak M, Males J, Marić A Tags: Coll Antropol Source Type: research

Allergic enterocolitis with protein-losing enteropathy in a 5-month-old girl: a case report.
We report the case of a 5-month-old female infant who had allergic enterocolitis with protein-losing enteropathy and had low birth weight. Until the age of 4 months, she was fed only breast milk and did not experience any related problems. When she was 5-months-old, she was admitted to our hospital with the chief complaints of vomiting and diarrhea. She had whole body edema, thoracic and abdominal ascites, and bloody stools. Laboratory examinations showed the presence of hypoalbuminemia, hypogammaglobulinemia, and an elevated CRP level. Subsequently, she was fed an elemental diet with enteral tube feeding, and her conditio...
Source: Arerugi - November 1, 2013 Category: Allergy & Immunology Authors: Watanabe T, Fukuie T, Tajima I, Nomura I Tags: Arerugi Source Type: research

Feeding Felix: overcoming an early onset of Crohn’s disease
Felix At just 3-months-old, Felix’s stool was regularly showing traces of blood. Alarmed, his mother Jessica Hsu quickly brought her young son to see his pediatrician, who referred Felix to be seen by Boston Children’s Hospital pediatric gastroenterologist Athos Bousvaros, MD, MPH. Gastrointestinal bleeding in infants is a fairly common problem, often the result of a change in diet or possibly a food allergy. Because Felix was still in the nursing stage, Bousvaros had Jessica remove some potential allergy triggers from her diet to keep traces of them from eventually ending up in her breast milk, and in turn, i...
Source: Thrive, Children's Hospital Boston - September 27, 2013 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Diseases & conditions Our patients’ stories Bousvaros Inflammatory Bowel Disease Inflammatory Bowel Disease Center our patients' stories Source Type: news

Taste test
When describing how most kids react to a plate of their least favorite foods, the term melodramatic would be an understatement. “If I have one more bite of broccoli, I’m going to be sick!” “Yuck! Spinach again? It makes me gag.” But for a small portion of kids, these terms aren’t exaggerations; they’re medically accurate statements. Cameron Ledin is one of those children. The 8-year-old was recently diagnosed with eosinophilic esophagitis (EoE), a severe allergic inflammation of the esophagus that causes his body to have terrible reactions to a wide range of foods. When a person wi...
Source: Thrive, Children's Hospital Boston - May 21, 2013 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Asthma & allergies Diseases & conditions Food allergies (EoE) clinical trial food allergy Eitan Runinstein eosinophilic esophagitis Eosinophilic Gastrointestinal Disease (EGID) Program John Lee Source Type: news