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Total 98 results found since Jan 2013.
Four thermostatic steps: A novel CRISPR-Cas12-based system for the rapid at-home detection of respiratory pathogens
In this study, we developed a new nucleic acid detection system, referred to as 4 Thermostatic steps (4TS), which innovatively allows all the detection processes to be completed in a constant temperature device, which performs extraction, amplification, cutting of targets, and detection within 40 min. The assay can specifically and sensitively detect five respiratory pathogens, namely SARS-CoV-2, Mycoplasma felis (MF), Chlamydia felis (CF), Feline calicivirus (FCV), and Feline herpes virus (FHV). In addition, a cost-effective and practical small-scale reaction device was designed and developed to maintain stable reaction c...
Source: Herpes - May 11, 2023 Category: Infectious Diseases Authors: Jianhua Fang Jing Liu Na Cheng Xiuhua Kang Zhanchao Huang Guoyu Wang Xiaofeng Xiong Tian Lu Zhenghua Gong Zhigang Huang Jun Che Tianxin Xiang Source Type: research
Immunological Facet and Inception after Post-COVID-19 Vaccination
Infect Disord Drug Targets. 2023 Apr 6. doi: 10.2174/1871526523666230406100146. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induced coronavirus disease 2019 (COVID-19) pandemic has produced an unparalleled setback for the world's economy and health. One of the best therapies to significantly lower severe illness and mortality from SARS-CoV-2 infection is vaccination. Worldwide vaccination campaigns are being implemented. New-onset autoimmune problems, such as immune thrombotic thrombocytopenia, autoimmune liver disorders, IgA nephropathy, Guillain-Barré syndrome, systemic lup...
Source: Infectious Disorders Drug Targets - April 11, 2023 Category: Infectious Diseases Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research
Occurrence and Economic Impact of Cystic Echinococcosis in Cattle Slaughtered in the Matabeleland Region, Zimbabwe
This study was conducted in the Matabeleland region of Zimbabwe to determine the incidence of cystic echinococcosis in bovines.METHODS: Meat inspection records from 2011 through 2021 kept at licensed abattoirs in the Matabeleland region were used to generate annual total figures of bovines slaughtered in the region, together with the corresponding number of organs condemned due to cystic echinococcosis. Descriptive statistics showing the overall incidence in each year, incidence per district, and cysts in infected organs were expressed as a percentage of the total number of cattle slaughtered per category.RESULTS: Bulawayo...
Source: Acta Tropica - April 8, 2023 Category: Infectious Diseases Authors: Machakwa Jairus Chivheya Jeff Chimbo Jeffrey Sungirai Marvelous Source Type: research
Sociodemographic and Clinical Factors Associated with Treatment Outcomes for Drug-resistant Tuberculosis
The objective of this study was to evaluate the sociodemographic, radiological, clinical, and outcome characteristics and assess the determinants of unfavorable outcomes in DR-TB. The descriptive-analytical study was carried out in a reference outpatient clinic in Rio de Janeiro, Brazil, among DR-TB cases that received treatment between February 2016 and October 2020, using descriptive statistics, χ2 test, and logistic regression multivariate. Of the 148 cases, 12.2% were resistant to rifampicin, 12.2% were resistant to isoniazid, 18.2% were polyresistant, 56.1% multidrug resistant, and 1.3% were extensively drug resistan...
Source: Am J Trop Med Hyg - October 31, 2022 Category: Infectious Diseases Authors: Ana Carolina de Oliveira Jeronymo Neves Ana Paula Gomes Dos Santos Regielle Luiza de Medeiros Ana J úlia de Oliveira Jeronymo Guilherme Coelho Neves Isabela Neves de Almeida Fernanda Carvalho de Queiroz Mello Afr ânio Lineu Kritski Source Type: research
Latest in COVID-19 Vaccine 'Candidates' Race
This article tries to give an overview of vaccine 'candidates' development and clinical trials, and it mentions some challenges of using these vaccines for managing SARS-CoV-2.PMID:35984031 | DOI:10.2174/1871526522666220818124416
Source: Infectious Disorders Drug Targets - August 19, 2022 Category: Infectious Diseases Authors: Manar Fayiz Atoum Dalia Abu Zreig Laith M Abu Zreig Source Type: research
