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Infectious Disease: Outbreaks
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Total 533 results found since Jan 2013.
Single-Chain Antibodies Directed to Norovirus GI.1 and GII.4 and Their Use
Vaccines and therapies to prevent and treat Norovirus infections are not available, despite the worldwide prevalence of Norovirus infections. Outbreaks of human gastroenteritis attributable to Norovirus commonly occur in group settings, such as hospitals, nursing homes, schools, dormitories, cruise ships and military barracks. This application claims isolated VHH monoclonal antibodies that specifically bind to a Norovirus polypeptide. Llama-derived single chain antibody fragments (also called VHH) are small, recombinant monoclonal antibodies of 15 kDa ( “nanobodies”) with several advantages over conventional antibodies...
Source: NIH OTT Licensing Opportunities - March 1, 2017 Category: Research Authors: ajoyprabhu3 Source Type: research
Synergistic Internal Ribosomal Entry Site (IRES) —MicroRNA-Based Approach for Attenuation of Flaviviruses and Live Vaccine Development
Many members of theFlaviviridae family are emerging and reemerging human pathogens that have caused outbreaks of devastating and often fatal diseases and represent a serious public health problem on a global scale. There is no single attenuation strategy that exists which is sufficient to prepare a safe, efficacious and immunogenic live attenuated virus vaccine that will work universally forFlaviviridae. This patent application claims live attenuated flavivirus vaccines, live attenuated multivalent flavivirus vaccines, and methods of preventing flavivirus infections as well as methods of making the vaccines claimed in the ...
Source: NIH OTT Licensing Opportunities - March 1, 2017 Category: Research Authors: ajoyprabhu3 Source Type: research
Yellow fever in the Americas
(NIH/National Institute of Allergy and Infectious Diseases) The large outbreak of yellow fever occurring in rural Brazil deserves careful attention by world health authorities, notes NIAID director Anthony S. Fauci, M.D. Writing in a Perspectives piece for NEJM, Dr. Fauci and his associate Catharine I. Paules, M.D., note that this latest outbreak of a serious mosquito-borne virus comes as Zika virus, which is spread by the same mosquito as yellow fever virus, continues to affect countries throughout the Americas.
Source: EurekAlert! - Infectious and Emerging Diseases - March 8, 2017 Category: Infectious Diseases Source Type: news
GSU researcher gets $4.1 million to develop Ebola drug
Dr. Christopher Basler, a Georgia State University professor in the Institute of Biomedical Sciences and director of the Center for Microbial Pathogenesis, received a $4.1 million grant to develop a drug to combat the Ebola virus.
The 2014 Ebola outbreak in West Africa resulted in 28,000 infections and 11,000 deaths, the largest known occurrence of the disease, according to the World Health Organization.
The National Institute of Allergy and Infectious Diseases, a division of the National Institutes…
Source: bizjournals.com Health Care:Biotechnology headlines - March 14, 2017 Category: Biotechnology Authors: Ellie Hensley Source Type: news
Yellow Fever Vaccine Advised for Travel to Brazil ' s Rio, Sao Paulo States Yellow Fever Vaccine Advised for Travel to Brazil ' s Rio, Sao Paulo States
The World Health Organization on Monday recommended that travelers to rural areas in the states of Rio de Janeiro and Sao Paulo get yellow fever vaccinations, as Brazil works to contain an outbreak of the virus in the country ' s southeast.Reuters Health Information
Source: Medscape Allergy Headlines - March 21, 2017 Category: Allergy & Immunology Tags: Infectious Diseases News Source Type: news
Scientists Start Second Phase Of Zika Vaccine Testing
Researchers at Houston’s Baylor College of Medicine last week began Phase 2 clinical trials for a Zika vaccine that is expected to have results as early as the end of this year.
Andrew Pekosz, a professor of microbiology and immunology at Johns Hopkins University’s Bloomberg School of Public Health, praised the vaccine’s potential to prevent disease, as well as how quickly clinical trials have taken place.
“It’s really been a light-speed endeavor,” Pekosz, who was not involved in the vaccine’s testing or development at the National Institute for Allergy and In...
Source: Science - The Huffington Post - April 3, 2017 Category: Science Source Type: news
New Cholera Vaccine for Adult Travelers New Cholera Vaccine for Adult Travelers
Here ' s what you need to know for adult patients who are traveling to cholera outbreak areas and who may be candidates for the new cholera vaccine.CDC Expert Commentary
Source: Medscape Allergy Headlines - April 17, 2017 Category: Allergy & Immunology Tags: Family Medicine/Primary Care Commentary Source Type: news
Italy Warns of Measles Epidemic as Vaccine Debate Rages Italy Warns of Measles Epidemic as Vaccine Debate Rages
Italy said on Wednesday it was suffering a measles epidemic following a fall-off in vaccinations, as the United States issued a warning to visitors about the outbreak of the potentially fatal disease.Reuters Health Information
Source: Medscape Allergy Headlines - April 20, 2017 Category: Allergy & Immunology Tags: Public Health & Prevention News Source Type: news
Vaccination Gaps Lead to Dangerous Measles Outbreaks in Europe - ECDC Vaccination Gaps Lead to Dangerous Measles Outbreaks in Europe - ECDC
Gaps in vaccination coverage against measles have lead to several outbreaks of the highly-contagious disease in Europe in the past year, with both children and young adults affected, health officials said on Monday.Reuters Health Information
Source: Medscape Allergy Headlines - April 25, 2017 Category: Allergy & Immunology Tags: Pathology & Lab Medicine News Source Type: news
The World Is Not Ready for the Next Pandemic
Across China, the virus that could spark the next pandemic is already circulating. It’s a bird flu called H7N9, and true to its name, it mostly infects poultry. Lately, however, it’s started jumping from chickens to humans more readily–bad news, because the virus is a killer. During a recent spike, 88% of people infected got pneumonia, three-quarters ended up in intensive care with severe respiratory problems, and 41% died.
What H7N9 can’t do–yet–is spread easily from person to person, but experts know that could change. The longer the virus spends in humans, the better the chance that i...
Source: TIME.com: Top Science and Health Stories - May 4, 2017 Category: Consumer Health News Authors: Bryan Walsh Tags: Uncategorized CDC Disease ebola Gates Foundation MERS outbreak pandemic Zika Source Type: news
At Least 1 Person Dead From New Ebola Outbreak In Democratic Republic Of Congo
One person has died from a new outbreak of the Ebola virus in the Democratic Republic of Congo, the World Health Organization confirmed Friday.
The country has reported nine suspected cases of the virus and three deaths since April 22, according to WHO communications officer Christoper Lindmeier. Out of the three deaths, one tested positive for Ebola.
The #Ebola case in the Democratic Republic of Congo was confirmed by a national reference laboratory in Kinshasa #DRC— WHO (@WHO) May 12, 2017
The cases were discovered in Aketi, a remote region without much access to health facilities, WHO communications offi...
Source: Science - The Huffington Post - May 12, 2017 Category: Science Source Type: news
Assessment of thunderstorm-induced asthma using Google Trends
An asthma outbreak of hospitalizations and deaths was noticed in Australia (November 2016) and in Kuwait (December 2016). This outbreak was clearly demonstrated using Google Trends (GT), a Web-based surveillance tool of interest in clinical practice.
Source: Journal of Allergy and Clinical Immunology - June 1, 2017 Category: Allergy & Immunology Authors: Jean Bousquet, Robyn E. O ’Hehir, Josep M. Anto, Genaro D’Amato, Ralf Mösges, Peter W. Hellings, Michiel Van Eerd, Aziz Sheikh Source Type: research
Polio Outbreak in Syria Poses Vaccination Dilemma for WHO Polio Outbreak in Syria Poses Vaccination Dilemma for WHO
Vaccinating too few children in Syria against polio because the six-year-old war there makes it difficult to reach them risks causing more cases in the future, the World Health Organization (WHO) said on Friday, posing a dilemma after a recent outbreak.Reuters Health Information
Source: Medscape Allergy Headlines - June 12, 2017 Category: Allergy & Immunology Tags: Infectious Diseases News Source Type: news
FDA Science: Working at the speed of emerging technologies
FDA Acting Chief Scientist Luciana Borio
By Luciana Borio, M.D.
Let’s face it, we’ve all gotten used to nearly instant access to almost anything.
Today, with a tap of an app, we order a car ride, a book, or pizza for dinner. Need to navigate past traffic in downtown city streets? No problem. There’s an app for that, too.
Some may wonder: Why hasn’t rapid medical product development partaken of this need for speed that has reshaped other sectors of our economy? Well, in many ways, it has.
Innovation is happening extraordinarily fast in the biomedical sciences and at FDA. As FDA’s Acting Chief Scientist responsible...
Source: Mass Device - June 22, 2017 Category: Medical Devices Authors: Danielle Kirsh Tags: Blog FDA Voice Source Type: news
