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Checkpoint inhibitor –induced autoimmune central nervous system disorder in patients with metastatic melanoma and Hodgkin’s lymphoma
ConclusionsWe demonstrate that symptoms of immune checkpoint inhibitor –induced encephalitis can be unspecific, and radiological findings are often inconspicuous. Thus, cerebrospinal fluid analysis is the most important examination to achieve a correct diagnosis, which in turn is decisive for a rapid start of therapy.
Source: Clinical and Experimental Neuroimmunology - March 11, 2021 Category: Neurology Authors: Nora M öhn, Kurt‐Wolfram Sühs, Yenny Angela, Martin Stangel, Philipp Ivanyi, Gernot Beutel, Ralf Gutzmer, Thomas Skripuletz, Imke Grimmelmann Tags: ORIGINAL ARTICLE Source Type: research

Checkpoint inhibitor induced autoimmune central nervous system disorder in patients with metastatic melanoma and Hodgkin lymphoma
ConclusionsWe demonstrate that symptoms of immune checkpoint inhibitor induced encephalitis can be unspecific and radiological findings are often inconspicuous. Thus, cerebrospinal fluid analysis is the most important examination to achieve a correct diagnosis which in turn is decisive for a rapid start of therapy.
Source: Clinical and Experimental Neuroimmunology - February 15, 2021 Category: Neurology Authors: Nora M öhn, Kurt‐Wolfram Sühs, Yenny Angela, Martin Stangel, Philipp Ivanyi, Gernot Beutel, Ralf Gutzmer, Thomas Skripuletz, Imke Grimmelmann Tags: ORIGINAL ARTICLE Source Type: research

Inflammatory myopathy following acute meningoccemia in a properdin-deficient patient: A case report.
CONCLUSION: Post-infectious inflammatory myopathy should be suspected in case of severe and persistent myalgia associated with rhabdomyolysis following an IMD, after exclusion of pyomyositis especially. A short course of corticosteroids seems to be effective. PMID: 31735371 [PubMed - as supplied by publisher]
Source: Revue de Medecine Interne - November 19, 2019 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research