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Infectious Disease: Herpes
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Total 364 results found since Jan 2013.
Quantitative Herpes Simplex Virus Concentrations in Neonatal Infection
Neonatal herpes simplex virus (HSV) infection fortunately is uncommon, occurring in an estimated 1 in 3200 deliveries in the US. Perinatal HSV infection clinically is categorized as skin, eye, and/or mouth (SEM) disease, central nervous system (CNS) disease, or disseminated disease.1 Clinical trials conducted by the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group over the course of 40 years have demonstrated these clinical classifications to be predictive of both morbidity and mortality.
Source: The Journal of Pediatrics - February 5, 2015 Category: Pediatrics Authors: Scott H. James, David W. Kimberlin Tags: Editorial Source Type: research
Herpes Zoster More Common Than Thought in Children Herpes Zoster More Common Than Thought in Children
A population-based study showed that herpes zoster incidence among only children who had varicella infection is higher than previously reported. Medscape Medical News
Source: Medscape Allergy Headlines - February 23, 2015 Category: Allergy & Immunology Tags: Pediatrics News Source Type: news
Human herpes virus reactivations and dynamic cytokine profiles in patients with cutaneous adverse drug reactions—a prospective comparative study
ConclusionHHV‐6 reactivation was only observed in DRESS patients, not in any other cADR. In DRESS patients, some proinflammatory cytokines were significantly lower before or during HHV‐6 reactivation.This article is protected by copyright. All rights reserved.
Source: Allergy - January 1, 2015 Category: Allergy & Immunology Authors: Yi‐Chun Chen, Hou‐Hsien Chiang, Yung‐Tsu Cho, Chia‐Ying Chang, Kai‐Lung Chen, Che‐Wen Yang, Yi‐Hsuan Lee, Chia‐Yu Chu Tags: Original Article: Skin and Eye Diseases Source Type: research
Methotrexate and biologics linked to higher zoster risk in psoriasis
The combination of methotrexate and biologics for the treatment of psoriasis may increase the risk of herpes zoster infection, according to a large, database cohort study published in JAMA Dermatology.
Analysis of medical records for 95,941 patients with psoriasis showed treatment with both...
Source: Skin and Allergy News - March 22, 2015 Category: Dermatology Tags: CME-candidate SAN Psoriasis SAN Journals SAN Clinical News SAN News FPN Journals FPN News Source Type: news
HIV levels fell in HSV-2–seronegative patients taking valacyclovir
HIV levels declined in patients who did not have herpes but took the antiherpes drug valacylovir in a double-blind placebo-controlled crossover trial.
The study showed that the drug “likely reduced HIV levels by interfering directly with HIV’s reproductive machinery and did not require the...
Source: Skin and Allergy News - March 23, 2015 Category: Dermatology Tags: IMN Journals IMN News IMN Infectious Diseases FPN Journals FPN News FPN Infectious Diseases Source Type: news
PAS: Use high-dose acyclovir to treat HSV-infected infants
SAN DIEGO – Infants given high-dose acyclovir for the treatment of herpes simplex virus (HSV) infections experienced a number of adverse reactions, including seizure, hypotension, and thrombocytopenia, according to the results of a new study, but it is unclear if the root cause of these events is...
Source: Skin and Allergy News - May 21, 2015 Category: Dermatology Tags: FPN Conferences PED Conferences SAN Conference News FPN News FPN Child & Adolescent Medicine FPN Dermatology FPN Infectious Diseases PED News Source Type: news
Herpes zoster ophthalmicus reactivation following maxillary sinus lift operation: A case report.
CONCLUSIONS: Dermatological diseases should always be kept in mind during the differential diagnosis of orofacial pain. In this case the proximity of the operation site and affected area gave rise to the idea that surgical trauma had a possible role in the reactivation of the virus. However, the process of reactivation is not entirely understood and requires further investigations. Early diagnosis is essential for HZO in order to avoid debilitating complications such as postherpetic neuralgia and blindness.
PMID: 26021228 [PubMed - in process]
Source: European Journal of Oral Implantology - June 1, 2015 Category: Dentistry Authors: Baş B, Özden B, Özdemir M, Yüksel EP Tags: Eur J Oral Implantol Source Type: research
Calcium spirulan derived from inhibits herpes simplex virus 1 attachment to human keratinocytes and protects against herpes labialis
Chronic infections with herpes simplex virus (HSV) type 1 are highly prevalent in populations worldwide and cause recurrent oral lesions in up to 40% of infected subjects.
Source: Journal of Allergy and Clinical Immunology - September 2, 2015 Category: Allergy & Immunology Authors: Julia Mader, Antonio Gallo, Tim Schommartz, Wiebke Handke, Claus-Henning Nagel, Patrick Günther, Wolfram Brune, Kristian Reich Source Type: research
Psoriasis and herpes are most stigmatized dermatologic conditions
Attitudes toward psoriasis and herpes are significantly more stigmatizing than are perceptions of other dermatologic conditions, reported Dr. Jessica M. Donigan and her associates from Massachusetts General Hospital in...
Source: Skin and Allergy News - September 9, 2015 Category: Dermatology Source Type: news
Generalized targetoid eruption in a man with HIV
A 36-year-old man with a long-standing history of HIV presented with a 1-month history of a generalized asymptomatic centrifugal skin eruption. He reported a new sexual partner over the past few months and a history of penicillin allergy. He denied any history of arthritis, herpes simplex infection, or new medications. The physical examination revealed scattered erythematous macules and annular patches on his scalp, chest, arms, palms, legs, and soles, with a few pustules and ulcerations on his groin (Figs 1 and 2).
Source: Journal of the American Academy of Dermatology - September 14, 2015 Category: Dermatology Authors: Megan Morrison, Melba Estrella, Brian Schapiro, Daniel Stewart Tags: Images in dermatology Source Type: research
GATA2 deficiency underlying severe blastomycosis and fatal herpes simplex virus–associated hemophagocytic lymphohistiocytosis
We describe an 18-year-old woman with lymphedema who developed severe blastomycosis and fatal hemophagocytic lymphohistiocytosis (HLH) associated with disseminated herpes simplex virus-1 (HSV-1) infection.
Source: Journal of Allergy and Clinical Immunology - September 19, 2015 Category: Allergy & Immunology Authors: Michael A. Spinner, Jennifer P. Ker, Charles J. Stoudenmire, Oluwole Fadare, Emily M. Mace, Jordan S. Orange, Amy P. Hsu, Steven M. Holland Tags: Letter to the Editor Source Type: research
Shingles vaccine protection lasted 5-6 years in autoimmune disease patients
Protection against shingles appeared to wane between the fifth and sixth years after patients with autoimmune diseases received the live herpes zoster vaccine, according to a large retrospective cohort study presented at the annual meeting of the American College of Rheumatology.
In contrast,...
Source: Skin and Allergy News - November 8, 2015 Category: Dermatology Source Type: news
Stroke risk rose in autoimmune disease patients after herpes zoster
Stroke risk was 50% higher in the month after patients with autoimmune diseases developed herpes zoster, compared with the next 2-6 years, according to Dr. Leonard H. Calabrese.
“These data provide urgency for developing strategies to reduce the risk of varicella zoster virus in vulnerable...
Source: Skin and Allergy News - November 8, 2015 Category: Dermatology Source Type: news
Non-Canonical (RANKL-Independent) Pathways of Osteoclast Differentiation and Their Role in Musculoskeletal Diseases
Abstract
Osteoclasts are multinucleated cells derived from mononuclear phagocyte precursors (monocytes, macrophages); in the canonical pathway of osteoclastogenesis, these cells fuse and differentiate to form specialised bone-resorbing osteoclasts in the presence of receptor activator for nuclear factor kappa B ligand (RANKL). Non-canonical pathways of osteoclastogenesis have been described in which several cytokines and growth factors are able to substitute for RANKL. These humoral factors can generally be divided into those which, like RANKL, are tumour necrosis family (TNF) superfamily members and those which a...
Source: Clinical Reviews in Allergy and Immunology - November 17, 2015 Category: Allergy & Immunology Source Type: research
Psoriatic arthritis treatment and the risk of herpes zoster
Conclusions
In our database, the risk of HZ was significantly increased with age, treatment with steroids, and combination of anti-TNF-α agents and c-DMARDs, but not with c-DMARDs or anti-TNF-α therapy alone. Time to HZ event was shorter in patients treated with anti -TNF-α agents.
Source: Annals of the Rheumatic Diseases - December 11, 2015 Category: Rheumatology Authors: Zisman, D., Bitterman, H., Shalom, G., Feldhamer, I., Comanesther, D., Batat, E., Greenberg-Dotan, S., Cohen, S., Cohen, A. D. Tags: Immunology (including allergy), Biological agents, Connective tissue disease, Degenerative joint disease, Drugs: musculoskeletal and joint diseases, Musculoskeletal syndromes, Rheumatoid arthritis, Epidemiology Clinical and epidemiological research Source Type: research
