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No impact of helminth coinfection in patients with smear positive tuberculosis on immunoglobulin levels using a novel method measuring Mycobacterium tuberculosis-specific antibodies
Helminth/tuberculosis (TB)-coinfection can reduce cell-mediated immunity against Mycobacterium tuberculosis (Mtb) and increase disease severity, although the effects are highly helminth species dependent. Mtb hav...
Source: Allergy, Asthma and Clinical Immunology - June 29, 2023 Category: Allergy & Immunology Authors: Giggil Pushpamithran, Camilla Skoglund, Fanny Olsson, Melissa M éndez-Aranda, Thomas Schön, Mårten Segelmark, Olle Stendahl, Robert H. Gilman and Robert Blomgran Tags: Research Source Type: research

Bronchial inflammation, respiratory symptoms and lung function in patients who finished treatment for pulmonary tuberculosis: is it the beginning of a new disease?
Conclusion: This study suggests the existence of different celullar patterns once the treatment has finished and supports the basis of a treatment hypothesis.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Palma, I., Castro Zorrilla, L., Resguardo, A., Martinez, D., Troncoso, D., Cruz, V., Vina, J., Alves, L., Natiello, M., Estevan, R., Lazari, N., Medin, M. I., Inwentarz, S., Videla, A., Palmero, D. Tags: Allergy and immunology Source Type: research

Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California
Conclusions: Residential proximity to road traffic volumes and traffic density were associated with increased all-cause mortality in patients undergoing treatment for active tuberculosis even after adjusting for multiple demographic, socioeconomic, and clinical factors, suggesting that TB patients are susceptible to the adverse health effects of traffic-related air pollution. https://doi.org/10.1289/EHP1699 Received: 31 January 2017 Revised: 18 August 2017 Accepted: 23 August 2017 Published: 29 September 2017 Address correspondence to R.J. Blount, Divisions of Pulmonary and Critical Care Medicine and Pediatric Pulmon...
Source: EHP Research - September 29, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Effects of Orally Ingested Arsenic on Respiratory Epithelial Permeability to Bacteria and Small Molecules in Mice
Conclusions: Peroral arsenic has little effect on local airway immune responses to bacteria but compromises respiratory epithelial barrier integrity, increasing systemic translocation of inhaled pathogens and small molecules. https://doi.org/10.1289/EHP1878 Received: 09 March 2017 Revised: 14 August 2017 Accepted: 16 August 2017 Published: 28 September 2017 Address correspondence to M.B. Fessler, National Institute of Environmental Health Sciences, 111 T.W. Alexander Dr., P.O. Box 12233, Maildrop D2-01, Research Triangle Park, NC 27709 USA. Telephone: (919) 541-3701. Email: fesslerm@niehs.nih.gov *Current address: UN...
Source: EHP Research - September 28, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Chronic granulomatous disease diagnosed in adulthood- Report of 2 Cases
We report 2 cases with CGD to emphasize that all granuloma forming diseases are not tuberculosis (TB), CGD must be considered in differential diagnosis in adults in populations with high incidence of consanguineous marriagesCase 1: 26 years old female patient has been on TB treatment for 5 months was admitted with respiratory failure. Although her initial sputum and culture negative for AFB, granulomatous inflammation was observed by surgical lung biopsy. Because of no response to treatment, patient was referred to our clinic with suspicion of MDR-TB. Galactomannan, cultures and 3 ARB results were negative. In medical hist...
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Kilic, A. I., Tokyay, D. A., Bodur, Y., Aksoy, E., Aktas, O., Tokgöz Akyil, F., Sevim, T. Tags: 5.3 Allergy and Immunology Source Type: research