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Infectious Disease: Osteomyelitis
Nutrition: Calcium

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Total 61 results found since Jan 2013.

Seasonal Variation and Global Public Interest in the Internet Searches for Osteoporosis
CONCLUSIONS: Google search query volumes related to osteoporosis follow strong seasonal patterns with late winter peaks and summer troughs. Further studies aimed at elucidating the possible mechanisms behind seasonality in osteoporosis are needed. Moreover, Internet data including the top rising topics may alert physicians to strengthen the propaganda of osteoporosis timely, so as to further promote the development of public health interventions.PMID:34189139 | PMC:PMC8195644 | DOI:10.1155/2021/6663559
Source: Biomed Res - June 30, 2021 Category: Research Authors: Chao Wang Xiong Shu Jianfeng Tao Yanzhuo Zhang Yue Yuan Chengai Wu Source Type: research

What's the Connection between Fever and Atraumatic Leg Pain?
​BY ADRIANA PORTO, MD; KELLY LEVASSEUR, DO; & SHANNA JONES, MDA 7-year-old girl presented to the emergency department with intermittent low-grade fever over the previous six days. She also had a sore throat, cough, and nasal congestion. Her mother reported a fever of 105°F with vomiting, cough, and congestion on the day of her presentation. She also noted that the patient complained of right leg pain and refused to walk or bear weight on her right leg, which was new the day of presentation. The patient pointed to the back of her right calf when asked where the pain was located. Her mother said the patient did not ha...
Source: The Case Files - June 18, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Effect of Low-Frequency Pulsed Ultrasound on Drug Delivery, Antibacterial Efficacy, and Bone Cement Degradation in Vancomycin-Loaded Calcium Phosphate Cement.
CONCLUSIONS Low-frequency pulsed ultrasound can enhance vancomycin release, prolong the duration of vancomycin concentration at high levels, and accelerate the degradation rate of vancomycin-loaded CPC. PMID: 29415980 [PubMed - in process]
Source: Medical Science Monitor - February 10, 2018 Category: Research Tags: Med Sci Monit Source Type: research

Lower-Extremity Osteomyelitis Treatment Using Calcium Sulfate/Hydroxyapatite Bone Void Filler with Antibiotics Seven-Year Retrospective Study.
CONCLUSIONS: A bone void filler with antibiotic(s) using the percutaneous antibiotic delivery technique is a safe, reliable, and effective means to treat lower-extremity osteomyelitis with either oral or intravenous antibiotics for 4 weeks. PMID: 29932757 [PubMed - in process]
Source: Journal of the American Podiatric Medical Association - May 1, 2018 Category: Podiatry Authors: Karr JC Tags: J Am Podiatr Med Assoc Source Type: research

Interferon gamma ‐1b does not increase markers of bone resorption in autosomal dominant osteopetrosis
This article is protected by copyright. All rights reserved.
Source: Journal of Bone and Mineral Research - March 18, 2019 Category: Orthopaedics Authors: Erik A. Imel, Ziyue Liu, Dena Acton, Melissa Coffman, Netsanet Gebregziabher, Yan Tong, Michael J. Econs Tags: CLINICAL TRIAL Source Type: research

Interferon Gamma ‐1b Does Not Increase Markers of Bone Resorption in Autosomal Dominant Osteopetrosis
ABSTRACTIn autosomal dominant osteopetrosis type 2 (ADO2)CLCN7 mutations cause impaired osteoclast function. Severe consequences include skeletal fragility despite high bone mass, osteomyelitis, osteonecrosis, bone marrow failure, and severe cranial nerve impingement. There is no effective medical treatment for ADO2. We recruited subjects with ADO2 into a 14 ‐week, open‐label, pilot clinical trial of interferon gamma‐1b. Doses were titrated based on tolerability and if fasting serum C‐telopeptide (CTX) was<25% above baseline at week 8, targeting doses of 100  µg/m2 three times a week. The primary outcomes wer...
Source: Journal of Bone and Mineral Research - May 12, 2019 Category: Orthopaedics Authors: Erik A Imel, Ziyue Liu, Dena Acton, Melissa Coffman, Netsanet Gebregziabher, Yan Tong, Michael J Econs Tags: CLINICAL TRIAL Source Type: research

Iatrogenic risk of osteonecrosis of the jaw? Bone substitutes for dental implants: a warning from Japan.
Authors: Hibi H Abstract Commercial bone substitutes that are widely used for bone augmentation for dental implants are predisposing factors in the development of osteonecrosis of the jaw (ONJ), overlooking this situation may lead to serious problems. Most of these materials are supplied as inorganic porous granules of calcium phosphate, which have characteristics that exceed the bone resorption ability of normal osteoclasts; therefore, they can be equally regarded as existing antiresorptive necrotic bony granules in the body, i.e., micro-ONJs. In addition, because dental implants directly contact the surrounding b...
Source: Nagoya Journal of Medical Science - April 12, 2020 Category: International Medicine & Public Health Tags: Nagoya J Med Sci Source Type: research

Symptomatic hypercalcaemia following the use of calcium sulfate beads in periprosthetic joint infections
N Z Med J. 2022 Jun 10;135(1556):124-126.ABSTRACTCalcium sulfate beads (CSBs) are used as a method of delivery of antibiotics in periprosthetic joint infections, non-union and chronic osteomyelitis.[[1-3]] Symptomatic hypercalcaemia can occur as a complication following the insertion of CSBs however it is rare and few cases have been reported.[[4-7]] The cause of hypercalcaemia is poorly understood.PMID:35728255
Source: New Zealand Medical Journal - June 21, 2022 Category: General Medicine Authors: John Hugh Thwaites Julia Frances Thwaites Kevin Lau You Ted Tim Chuang Source Type: research