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Infectious Disease: Hepatitis C
Nutrition: Vitamins
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Total 161 results found since Jan 2013.
Protein Induced by Vitamin K Absence or Antagonist-II Versus Alpha-Fetoprotein in the Diagnosis of Hepatocellular Carcinoma: A Systematic Review With Meta-Analysis
CONCLUSION: This study reveals that PIVKA-II is a promising biomarker for identifying and tracking HCC, exhibiting greater accuracy than AFP. Our findings indicate that PIVKA-II outperforms AFP in detecting HCC across diverse racial groups and sample sizes, as well as in cases of HBV-related, HCV-related, or mixed-etiology HCC.PMID:37575350 | PMC:PMC10416192 | DOI:10.14740/jocmr4951
Source: Clin Med Res - August 14, 2023 Category: Research Authors: Abdallah Kobeissy Nooraldin Merza Alsadiq Al-Hillan Safa Boujemaa Zohaib Ahmed Mohamad Nawras Mohammed Albaaj Dushyant Singh Dahiya Yaseen Alastal Mona Hassan Source Type: research
Diagnostic Role of Tumor Markers for Hepatocellular Carcinoma in Liver Transplantation Candidates: An Analysis Using the Korean Organ Transplantation Registry Database
CONCLUSIONS The results of the present study indicate that pretransplant serum AFP and PIVKA-II were highly variably expressed in LT candidates with end-stage liver diseases; therefore, their values should be cautiously interpreted because their role in HCC diagnosis is limited.PMID:36097403 | DOI:10.12659/AOT.936937
Source: Annals of Transplantation - September 13, 2022 Category: Transplant Surgery Authors: Woo-Hyoung Kang Shin Hwang Jong Man Kim Kwang-Woong Lee Dong Jin Joo Young Kyoung You Je Ho Ryu Bong-Wan Kim Donglak Choi Dong-Sik Kim Yang Won Nah Source Type: research
All-trans retinoic acid inhibits HCV replication by downregulating core levels via E6AP-mediated proteasomal degradation
Biochem Biophys Res Commun. 2022 Jan 17;594:15-21. doi: 10.1016/j.bbrc.2022.01.052. Online ahead of print.ABSTRACTHere, we found that all-trans retinoic acid (ATRA), the most biologically active metabolite of vitamin A, strengthens the anti-viral defense mechanism of E6-associated protein (E6AP) that downregulates hepatitis C virus (HCV) Core levels via ubiquitin-dependent proteasomal degradation. For this effect, ATRA downregulated both protein and enzyme activity levels of DNA methyltransferase 1 and 3b and activated E6AP expression via promoter hypomethylation in HepG2 cells but not in Hep3B cells, in which p53 was abse...
Source: Biochemical and Biophysical Research communications - January 23, 2022 Category: Biochemistry Authors: Hye-Kyoung Lee Hyunyoung Yoon Kyung Lib Jang Source Type: research
Hepatic and gastrointestinal disturbances in Egyptian patients infected with coronavirus disease 2019: A multicentre cohort study
CONCLUSION: Few Egyptian patients with COVID-19 developed a significant liver injury. The independent variables affecting mortality were supplementary vitamin C intake, lung consolidation, ICU admission, and FIB-4 score.PMID:34790017 | PMC:PMC8567470 | DOI:10.3748/wjg.v27.i40.6951
Source: World Journal of Gastroenterology - November 18, 2021 Category: Gastroenterology Authors: Hend Ibrahim Shousha Shimaa Afify Rabab Maher Noha Asem Eman Fouad Ehab F Mostafa Mohammed A Medhat Amr Abdalazeem Hazem Elmorsy Miriam M Aziz Rateba S Mohammed Mohamed Ibrahem Hassan Elgarem Dalia Omran Mohamed Hassany Bassem Elsayed Ahmed Y Abdelaziz Mo Source Type: research
