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Infectious Disease: Hepatitis B
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Total 16723 results found since Jan 2013.
Oncogenic β-catenin-driven liver cancer is susceptible to methotrexate-mediated disruption of nucleotide synthesis
CONCLUSION: MTX is a promising chemotherapeutic agent for β-catenin hyperactive liver cancer. Since repurposing MTX has the advantages of lower risk, shorter timelines, and less investment in drug discovery and development, a clinical trial is warranted to test its efficacy in the treatment of β-catenin mutant liver cancer.PMID:37612257 | DOI:10.1097/CM9.0000000000002816
Source: Chinese Medical Journal - August 23, 2023 Category: General Medicine Authors: Fangming Liu Yuting Wu Baohui Zhang Shuhui Yang Kezhuo Shang Jie Li Pengju Zhang Weiwei Deng Linlin Chen Liang Zheng Xiaochen Gai Hongbing Zhang Source Type: research
The transmission of hepatitis B virus (HBV) infection from mother-to-infant (MTI) and the susceptibility of offspring to hepatitis B under intrauterine exposure to HBsAg
CONCLUSIONS: Therefore, we speculated that these signaling pathways and the genes within may be closely related to hepatitis B susceptibility and maternal hepatitis B inheritance. In this study, we showed that differentially expressed genes and signaling pathways may be valuable in preventing MTI transmission of HBV.PMID:37606146 | DOI:10.26355/eurrev_202308_33309
Source: European Review for Medical and Pharmacological Sciences - August 22, 2023 Category: Drugs & Pharmacology Authors: M-M Zhang X Liao H Wang Source Type: research
Serum Expression Level of MicroRNA-122 and its Significance in different Stages of Hepatitis B Virus Infection
This study aims to determine the serum expression level of miRNA-122 and its significance in the different stages of Hepatitis B virus infection. The study subjects were recruited and grouped for Hepatitis B associated with Chronic Hepatitis B infection, hepatic sclerosis, hepatocellular carcinoma, and healthy controls were also considered. Venous blood was collected from the participants including the controls and routine blood tests and quantification of miRNA-122 were done and analyzed in each case of hepatitis B infection and compared with that of healthy controls. The miRNA-122 was determined, which came to be highest...
Source: Mol Biol Cell - August 22, 2023 Category: Molecular Biology Authors: Shashi Prabha Singh Vandana Maurya Krishan Kumar Durgesh Singh Poonam Verma Dipan Samanta Manish Kumar Verma Source Type: research
The transmission of hepatitis B virus (HBV) infection from mother-to-infant (MTI) and the susceptibility of offspring to hepatitis B under intrauterine exposure to HBsAg
CONCLUSIONS: Therefore, we speculated that these signaling pathways and the genes within may be closely related to hepatitis B susceptibility and maternal hepatitis B inheritance. In this study, we showed that differentially expressed genes and signaling pathways may be valuable in preventing MTI transmission of HBV.PMID:37606146 | DOI:10.26355/eurrev_202308_33309
Source: Pharmacological Reviews - August 22, 2023 Category: Drugs & Pharmacology Authors: M-M Zhang X Liao H Wang Source Type: research
Serum Expression Level of MicroRNA-122 and its Significance in different Stages of Hepatitis B Virus Infection
This study aims to determine the serum expression level of miRNA-122 and its significance in the different stages of Hepatitis B virus infection. The study subjects were recruited and grouped for Hepatitis B associated with Chronic Hepatitis B infection, hepatic sclerosis, hepatocellular carcinoma, and healthy controls were also considered. Venous blood was collected from the participants including the controls and routine blood tests and quantification of miRNA-122 were done and analyzed in each case of hepatitis B infection and compared with that of healthy controls. The miRNA-122 was determined, which came to be highest...
Source: Mol Biol Cell - August 22, 2023 Category: Molecular Biology Authors: Shashi Prabha Singh Vandana Maurya Krishan Kumar Durgesh Singh Poonam Verma Dipan Samanta Manish Kumar Verma Source Type: research
The transmission of hepatitis B virus (HBV) infection from mother-to-infant (MTI) and the susceptibility of offspring to hepatitis B under intrauterine exposure to HBsAg
CONCLUSIONS: Therefore, we speculated that these signaling pathways and the genes within may be closely related to hepatitis B susceptibility and maternal hepatitis B inheritance. In this study, we showed that differentially expressed genes and signaling pathways may be valuable in preventing MTI transmission of HBV.PMID:37606146 | DOI:10.26355/eurrev_202308_33309
Source: European Review for Medical and Pharmacological Sciences - August 22, 2023 Category: Drugs & Pharmacology Authors: M-M Zhang X Liao H Wang Source Type: research
