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Total 1401 results found since Jan 2013.
With the Decongestant SNAFU, the FDA Tries Something New
It’s easy to understand how a medicine like phenylephrine got onto pharmacy shelves in the first place. The common decongestant, used most often as an ingredient in multidrug cold medications like DayQuil and Sudafed PE, was initially designated as “safe and effective” by the Food and Drug Administration (FDA) in 1976, when the agency was newly—and less stringently than today—greenlighting drugs that had been on the market for years before the agency had established any efficacy standards. After a full review of 14 studies (12 unpublished and two published) from pharmaceutical companies—...
Source: TIME: Health - September 14, 2023 Category: Consumer Health News Authors: Haley Weiss Tags: Uncategorized healthscienceclimate Source Type: news
Pro ‐inflammatory markers associated with COVID‐19‐related persistent olfactory dysfunction
ConclusionIFN pathway cytokines were found elevated in the olfactory microenvironment of COVID-19 persistent OD compared to those with no OD and no prior history of COVID-19 infection.
Source: International Forum of Allergy and Rhinology - September 7, 2023 Category: Allergy & Immunology Authors: Sophie S. Jang,
Kwang S. Pak,
Allyssa Strom,
Leslie Gomez,
Laura Kim,
Taylor A. Doherty,
Adam S. DeConde,
Allen F. Ryan,
Carol H. Yan Tags: ORIGINAL ARTICLE Source Type: research
Population-level trends in asthma and chronic obstructive pulmonary disease emergency department visits and hospitalizations before and during the coronavirus disease 2019 pandemic in the United States
Previous studies have identified reductions in exacerbations of chronic lung disease in many locales after onset of the coronavirus disease 2019 (COVID-19) pandemic.
Source: Annals of Allergy, Asthma and Immunology - August 22, 2023 Category: Allergy & Immunology Authors: Adam Gaffney, David U. Himmelstein, Steffie Woolhandler Source Type: research
News at a glance: A win for obesity drugs, NIH unionization roadblocks, and Mexican fireflies under threat
CONSERVATION
Researchers raise alarm over threat to Mexican fireflies
Scientists from the International Union for Conservation of Nature (IUCN) last week delivered a letter to the Mexican government requesting it regulate tourism centered on the threatened firefly species
Photinus palaciosi
. Endemic to Mexico’s Tlaxcala forests,
P. palaciosi
is one of the few species that glow in synchrony, offering an annual spectacle that attracts thousands of visitors during summer mating season. The letter describes how littering, artificial light, and noise interfere with the insects’ courtship and eg...
Source: ScienceNOW - August 10, 2023 Category: Science Source Type: news
News at a glance: A win for obesity drugs, a new infectious disease institute head, and Mexican fireflies under threat
CONSERVATION
Researchers raise alarm over threat to Mexican fireflies
Scientists from the International Union for Conservation of Nature (IUCN) last week delivered a letter to the Mexican government requesting it regulate tourism centered on the threatened firefly species
Photinus palaciosi
. Endemic to Mexico’s Tlaxcala forests,
P. palaciosi
is one of the few species that glow in synchrony, offering an annual spectacle that attracts thousands of visitors during summer mating season. The letter describes how littering, artificial light, and noise interfere with the insects’ courtship and eg...
Source: Science of Aging Knowledge Environment - August 10, 2023 Category: Geriatrics Source Type: research
Health Status and Inconveniences of Asthmatic Children During the First Year of the COVID-19 Pandemic
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):245-253. doi: 10.18502/ijaai.v22i3.13052.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic has been the most significant health concern in recent years, with respiratory symptoms being the most prominent. In children, asthma is the most prevalent chronic disease. Due to the similarities between the symptoms of these two conditions, we sought to assess the general health status of pediatric patients with asthma and their COVID-19-related difficulties during the first year of the pandemic in Iran. We collected data for this study by administering a questionnaire to the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Saber Gharagozlou Negin Rostamzadeh Mohammad Gharagozlou Source Type: research
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
Immune Profiling of SARS-CoV-2; What We Know and What We Don't Know
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):217-232. doi: 10.18502/ijaai.v22i3.13050.ABSTRACTCoronavirus disease 2019 (COVID-19), described as World War 3, is the current worldwide health challenge and nearly all countries have so far faced this disaster. There is still no cure because of the complicated pathogenesis, however, there are several studies on track investigating different aspects of the immune response to the virus. In this review, we will provide an overview of recent investigations that have analyzed immune cells in patients with COVID-19. We will then discuss the differences in immune profiles between ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Mahshid Zohouri Atri Ghods Mina Roshan Zamir Fazel Shokri Abbas Ghaderi Source Type: research
Health Status and Inconveniences of Asthmatic Children During the First Year of the COVID-19 Pandemic
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):245-253. doi: 10.18502/ijaai.v22i3.13052.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic has been the most significant health concern in recent years, with respiratory symptoms being the most prominent. In children, asthma is the most prevalent chronic disease. Due to the similarities between the symptoms of these two conditions, we sought to assess the general health status of pediatric patients with asthma and their COVID-19-related difficulties during the first year of the pandemic in Iran. We collected data for this study by administering a questionnaire to the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Saber Gharagozlou Negin Rostamzadeh Mohammad Gharagozlou Source Type: research
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
Immune Profiling of SARS-CoV-2; What We Know and What We Don't Know
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):217-232. doi: 10.18502/ijaai.v22i3.13050.ABSTRACTCoronavirus disease 2019 (COVID-19), described as World War 3, is the current worldwide health challenge and nearly all countries have so far faced this disaster. There is still no cure because of the complicated pathogenesis, however, there are several studies on track investigating different aspects of the immune response to the virus. In this review, we will provide an overview of recent investigations that have analyzed immune cells in patients with COVID-19. We will then discuss the differences in immune profiles between ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Mahshid Zohouri Atri Ghods Mina Roshan Zamir Fazel Shokri Abbas Ghaderi Source Type: research
Health Status and Inconveniences of Asthmatic Children During the First Year of the COVID-19 Pandemic
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):245-253. doi: 10.18502/ijaai.v22i3.13052.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic has been the most significant health concern in recent years, with respiratory symptoms being the most prominent. In children, asthma is the most prevalent chronic disease. Due to the similarities between the symptoms of these two conditions, we sought to assess the general health status of pediatric patients with asthma and their COVID-19-related difficulties during the first year of the pandemic in Iran. We collected data for this study by administering a questionnaire to the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Saber Gharagozlou Negin Rostamzadeh Mohammad Gharagozlou Source Type: research
Exosomes from Adipose Tissue-derived Mesenchymal Stem Cells Induce Regulatory T Cells in COVID-19 Patients
This study aimed to assess the effect of MSC-derived exosomes (MSC-Exo) on the differentiation of peripheral blood mononuclear cells (PBMCs) into Tregs from patients with COVID-19. Exosomes were isolated from adipose tissue-derived MSCs. PBMCs were separated from the whole blood of COVID-19 patients (n=20). Treg frequency was assessed before and 48 hours after treatment of PBMCs with MSC-Exo using flow cytometry. Expression of FOXP3 and cytokine genes, and the concentration of cytokines associated with Tregs, were assessed before and after treatment with MSC-Exo. The frequency of CD4+CD25+CD127- Tregs was significantly hig...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Morteza Motallebnezhad Ali Hazrati Hadi Esmaeili Gouvarchin Ghaleh Nematollah Jonaidi-Jafari Sanaz Abbaspour-Aghdam Kosar Malekpour Mehdi Yousefi Hossein Samadi Kafil Farhad Jadidi-Niaragh Leila Roshangar Hamed Valizadeh Morteza Izadi Majid Ahmadi Source Type: research
Immune Profiling of SARS-CoV-2; What We Know and What We Don't Know
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):217-232. doi: 10.18502/ijaai.v22i3.13050.ABSTRACTCoronavirus disease 2019 (COVID-19), described as World War 3, is the current worldwide health challenge and nearly all countries have so far faced this disaster. There is still no cure because of the complicated pathogenesis, however, there are several studies on track investigating different aspects of the immune response to the virus. In this review, we will provide an overview of recent investigations that have analyzed immune cells in patients with COVID-19. We will then discuss the differences in immune profiles between ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Mahshid Zohouri Atri Ghods Mina Roshan Zamir Fazel Shokri Abbas Ghaderi Source Type: research
