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Drug: Ciprofloxacin

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Discovery of inhibition of < em > Burkholderia cenocepacia, Pseudomonas aeruginosa < /em > and < em > Stenotrophomonas maltophilia < /em > by the Brown Rot Basidiomycete Fungus, < em > Postia placenta < /em >
This study wished to explore the production of antibacterial extracellular metabolites from plant pathogenic fungi. Fungal Culture Extracts (FCEs) were prepared from 10 fungi (Armillaria gallica, Clitocybe nebularis, Fusarium coeruleum, Fusarium oxysporum, Fusarium poae, Hymenoscyphus fraxineus, Nectria f.eliana, Phytophthora infestans, Phytophthora ramorum, Postia placenta), which were tested for activity against the CF pathogens, Pseudomonas aeruginosa (PA) (n=8), Burkholderia cenocepacia (n=2) and Stenotrophomonas maltophilia (n=2). In addition, FCE were assessed for their ability to alter antibiotic susceptibility in P...
Source: The Ulster Medical Journal - November 24, 2021 Category: General Medicine Authors: Rachael McIlroy David W Nelson B Cherie Millar Alan Murphy Juluri R Rao Damian G Downey John E Moore Source Type: research

Antibiotic resistance continues to rise
"Antibiotic resistance continues to rise," BBC News reports as, despite warnings, the number of antibiotic prescriptions in the UK continues to soar, as do new cases of resistant bacteria. Other news reports take different slants on the story, with The Daily Telegraph blaming the rise on hospitals and out of hours GPs. The news follows the publication of a new report by Public Health England on the English surveillance programme for antimicrobial utilisation and resistance (ESPAUR), which reports the change in antibiotic prescribing and resistance over recent years. The report highlights a number of key f...
Source: NHS News Feed - October 10, 2014 Category: Consumer Health News Tags: Medical practice Medication QA articles Source Type: news

Sustained prevention of biofilm formation on a novel silicone matrix suitable for medical devices.
In conclusion, the hydrogel/silicone composite represents a promising candidate material for medical devices that prevents bacterial colonization during long-term use. PMID: 26028273 [PubMed - as supplied by publisher]
Source: European Journal of Pharmaceutics and Biopharmaceutics - May 28, 2015 Category: Drugs & Pharmacology Authors: Steffensen SL, Vestergaard MH, Groenning M, Alm M, Franzyk H, Nielsen HM Tags: Eur J Pharm Biopharm Source Type: research

Impact of the medical specialty on knowledge regarding multidrug-resistant organisms and strategies toward antimicrobial stewardship
ConclusionsThere is substantial need for advanced training regarding MDRO and antibiotic stewardship, regardless of medical specialty.
Source: International Urology and Nephrology - April 21, 2017 Category: Urology & Nephrology Source Type: research

Characteristics of patients infected with Clostridioides difficile at a Saudi Tertiary Academic Medical Center and assessment of antibiotic duration
ConclusionMost patients in this study had hospital-acquired non-severe CDI and were largely exposed to antibiotics and acid suppression therapy. Therefore, such therapies should be revised for necessity.
Source: Gut Pathogens - February 17, 2021 Category: Microbiology Source Type: research

Treating urinary tract infections in public sector primary healthcare facilities in Cape Town, South Africa: A pharmaceutical perspective
CONCLUSION: Interventions are required to improve compliance with treatment recommendations as per the standard treatment guidelines, especially when selecting the appropriate antibiotic, duration of therapy and urine microscopy.PMID:36217859
Source: South African Medical Journal - October 11, 2022 Category: African Health Authors: N Keuler Y Johnson R Coetzee Source Type: research