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Drug: Methotrexate
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Current Medical Therapy for Sarcoidosis
Semin Respir Crit Care Med 2017; 38: 523-531 DOI: 10.1055/s-0037-1604032Most cases of sarcoidosis are mild and self-limited, with a spontaneous cure. However, in some patients, this disease may also be life-threatening, particularly when severe manifestations induce vital organ dysfunction. Sarcoidosis may also severely impair the quality of life through diverse, persistent disabling symptoms. To date, there is no curative treatment for sarcoidosis, but only anti-inflammatory drugs limiting the pathologic impact of sarcoidosis in reducing enhanced immunity reactions, granulomatous formation, and their consequences. Current...
Source: Seminars in Respiratory and Critical Care Medicine - July 27, 2017 Category: Respiratory Medicine Authors: Valeyre, Dominique Jeny, Florence Nunes, Hilario Tags: Review Article Source Type: research
New photobiomodulation protocol prevents oral mucositis in hematopoietic stem cell transplantation recipients —a retrospective study
The objective of this retrospective study was to evaluate the preventive effect of photobiomodulation (PBM) applied three times per week versus seven times per week in patients undergoing HSCT. The risk factors related to the incidence and severity of OM were also assessed. This was a retrospective study that evaluated 99 HSCT recipients who received different PBM protocols. Group I received three sessions per week, and group II received daily treatment. PBM was applied using a continuous-wave diode laser (InGaAlP; MM Optics, S ão Carlos, SP, Brazil) at a wavelength of 660 nm (visible-red) and a total radiant energy of 0...
Source: Lasers in Medical Science - August 24, 2017 Category: Laser Surgery Source Type: research
Stop Methotrexate in RA Patients for 2 Weeks After Flu Shot Stop Methotrexate in RA Patients for 2 Weeks After Flu Shot
A temporary suspension of methotrexate boosts the immune response to flu vaccination with no increase in rheumatoid arthritis (RA) disease activity, a randomized clinical trial shows.Medscape Medical News
Source: Medscape Medical News Headlines - November 5, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Baricitinib Eases Rheumatoid Arthritis Pain Baricitinib Eases Rheumatoid Arthritis Pain
The JAK inhibitor reduced pain in rheumatoid arthritis patients refractory to methotrexate more than a TNF inhibitor, a new analysis of RA-BEAM data shows.Medscape Medical News
Source: Medscape Medical News Headlines - November 8, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Interstitial and Cornual Ectopic Pregnancy: Conservative Surgical and Medical Management
ConclusionEarly diagnosis and timely management are key to the management of interstitial and cornual ectopic pregnancy. With expertise in ultrasound imaging and advances in laparoscopic skills progressively, conservative medical and surgical measures are being used to treat interstitial and cornual ectopic pregnancy successfully.
Source: The Journal of Obstetrics and Gynecology of India - November 28, 2017 Category: OBGYN Source Type: research
A risk prediction model for medical treatment failure in tubal pregnancy
This study aimed to identify the risk factors for medical treatment failure in tubal pregnancy and apply them to a risk prediction model.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 19, 2018 Category: OBGYN Authors: Jae Hoon Lee, Sunghoon Kim, Inha Lee, Jisun Yun, Bo Hyon Yun, Young Sik Choi, Byung Seok Lee, Seok Kyo Seo Tags: Full length article Source Type: research
' Best Survival Data Ever ' in Young T-Cell Leukemia Patients ' Best Survival Data Ever ' in Young T-Cell Leukemia Patients
Moving nelarabine to the front line and combining it with methotrexate improved 4-year disease-free survival in young patients with T-cell acute lymphoblastic leukemia.Medscape Medical News
Source: Medscape Medical News Headlines - May 22, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Disease Characteristics and Change in Arthritis Activity according to Treatment in Hepatitis B Surface Antigen-positive Rheumatoid Arthritis Patients: a Retrospective Chart Review Study.
Conclusion: RA medication use varied according to HBsAg-positivity. However, improvement in RA activity was not significantly affected by concomitant hepatitis B infection.
PMID: 29853822 [PubMed - in process]
Source: Journal of Korean Medical Science - June 2, 2018 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
Accelerated subcutaneous nodulosis in patients with rheumatoid arthritis treated with tocilizumab: a case series
ConclusionsTo the best of our knowledge, this is the first report describing accelerated subcutaneous nodulosis in a small case series of patients with rheumatoid arthritis treated with tocilizumab.
Source: Journal of Medical Case Reports - June 3, 2018 Category: General Medicine Source Type: research
Double the Risk for Neurotoxicity for Hispanic Kids From ALL Rx Double the Risk for Neurotoxicity for Hispanic Kids From ALL Rx
Minority children, notably Hispanics, are more susceptible to developing methotrexate-induced neurotoxicity than non-Hispanic children during treatment for acute lymphoblastic leukemia (ALL).Medscape Medical News
Source: Medscape Medical News Headlines - September 12, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
In Peripheral Spondyloarthritis, Early Biologic Needed In Peripheral Spondyloarthritis, Early Biologic Needed
New data from the CRESPA extension study show that the addition of methotrexate during biologic tapering has no significant effect on remission in peripheral spondyloarthritis.Medscape Medical News
Source: Medscape Medical News Headlines - October 11, 2018 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Medical News Today: Methotrexate and folic acid for rheumatoid arthritis
Doctors sometimes prescribe methotrexate for rheumatoid arthritis (RA), but it can lead to folic acid deficiencies. Learn more about managing this and other side effects.
Source: Health News from Medical News Today - October 29, 2018 Category: Consumer Health News Tags: Rheumatoid Arthritis Source Type: news
CIRT: Methotrexate Fails to Cut CV Events CIRT: Methotrexate Fails to Cut CV Events
Though negative, the results provide vital information on the underlying biology that connects inflammation with cardiovascular disease, experts say.Medscape Medical News
Source: Medscape Medical News Headlines - November 11, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news
Methotrexate Added to Biologic Eases Inflamed Skin Methotrexate Added to Biologic Eases Inflamed Skin
The combination of methotrexate and anti-TNF therapy can improve clinical response in patients with severe hidradenitis suppurativa, first results from a new study demonstrate.Medscape Medical News
Source: Medscape Medical News Headlines - February 8, 2019 Category: Consumer Health News Tags: Dermatology News Source Type: news
